lab animal quizzes ch 8-11

The incidence of spontaneous tumor development in rats and mice over two years of age is: (%)

87%.

When exposed to a male or the scent of a male, the females will begin estrus within three days. This is referred to as:

the Whitten effect.

When performing an intraperitoneal injection, where should the needle be placed to avoid contact with the internal organs?

Lower left quadrant

Which temperature and relative humidity range is appropriate for rats and mice?

65-75° F and 40-60% humidity

Latex gloves should be worn when handling rats or mice due to the possibility of the transmission of:

Leptospira.

Which term means that rats' and mice's teeth will continuously grow throughout their life?

Hypsodontic

Which infectious bacterial disease commonly found in mice and rats has zoonotic potential?

Leptospira

What is the average heart rate of a rat?

313-493 bpm

Which gender is B:

male

Which type of strain was developed as a result of genetic mutation in existing strains?

Coisogenic

Due to the fact that rats do not have which organ does bile continuously enter the duodenum?

Gallbladder

Which of the following is a result of the epiphyses of the bones that do not close in most rats?

Rats grow continuously throughout their life.

Animals that are the result of at least 20 generations of inbred mating are referred to as:

strain.

Mice that are kept near birds or are exposed to avian feces may acquire an infection with:

Histoplasma capsulatum.

When a female is exposed to a new male within four days of breeding, the existing pregnancy may be aborted and the female returns to estrus. This is referred to as:

the Bruce effect.

When males and females are continuously housed together, it is referred to as:

intensive breeding.

What procedure is being performed on the rat?

Gavage

What is the average lifespan of a rat?

26-40 months

An inexpensive restraining device for rats and mice that can be made from a household item would be:

plastic cone.

What is the maximum volume for a SQ injection on a mouse?

0.2 mL/10g

Which method of animal identification has a national database of animals' identification numbers so that information can be recovered if an animal is lost or stolen?

Microchipping

Which type of strain is developed when a mutation arises in one strain and is transferred to another through a series of back crossings?

Congenic

What is the average respiratory rate of a rat?

71-146 bpm

Which type of animal is derived by removing specific DNA sequences from one strain or species and inserting them into an ovum just after fertilization?

Transgenic

When males and females are housed separately, especially during the period the female is pregnant, it is referred to as:

nonintensive breeding

Which disease caused by Clostridium piliforme can be found in almost all species of laboratory animals?

Tyzzer's disease

What is the average daily water consumption of a rat?

22-33 mL

What is the maximum volume for a SQ injection on a rat?

0.8 mL/10g

Rattus norvegicus is commonly known as the brown or Norway rat.

t

This is normal dentation of rat and mouse incisors.

falsee

Because rats have a unique ability to adapt to new environments they are a good animal model for:

behavioral research.

Which route of administration of medication requires that the animal be anesthetized?

Intraosseous

A safe level of blood volume of the total body weight that can be collected from a rodent is:

6-7%

Which type of ectoparasite burrows into the dermis and may cause hair loss and pruritus?

Louse

Which of the following bedding materials for mice or rats may affect hepatic enzymes and could cause respiratory problems?

cedar shavings

Which condition in rats can be caused by low humidity levels?

Ringtail

Which animals have similar characteristics but are not genetically identical?

Stock

If a mouse has alopecia but not pruritis, which of the following should be suspected?

Barbering

Which gender is A:

Female

During a physical examination on a rat, which is one of the first observable signs of disease?

Unkept appearance

Which unique feature of rats makes them a good animal model for toxicology research?

The inability to vomit

The gestation period for a rat is:

approximately 22 days.

If a researcher needs tissues and bodily fluids that are noncontaminated in order to yield valid results, which method of euthanasia is acceptable?

Decapitation

Because of the similarity of the rat molar to humans, the rat is often used in which type of research studies?

Dental

If a rat has a wound, which of the following is not recommended for treatment?

Bandage the wound

Bandage the wound

Secretion of porphyrin is also called:

chromodacyorrhea.

Which age-related disease of rats and mice leads to muscular atrophy in the lumbar region and hindlimbs?

Radiculoneuropathy

What is the maintenance to effect of isoflurane on rats and mice?

0.3%

In which route of medication administration is the material first absorbed into the portal circulation before it reaches the systemic circulation?

Intraperitoneal

To evaluate the level of anesthesia in a rat, the best method to determine the animal is at a surgical stage of anesthesia would be:

failure to withdraw from a toe pinch.

Which blood collection procedure should only be performed if the animal is to be euthanized immediately following collection?

Cardiocentesis

Which vein is being drawn from on this mouse?

Lateral tail vein

What is the average daily feed consumption of a rat (per the text not the 8.1 chart)?

5 g of food per 100 g

What is the average daily water consumption of mice?

5-8 mL

The taxonomic name for the laboratory mouse is:

Mus musculus.

Noninfectious diseases in rats and mice can be related to:

husbandry.

Which is the most common vessel for use in intravenous injections in rats and mice?

Lateral tail vein

Rats and mice that have been randomly bred are termed:

stock.

What is the average heart rate of mice?

313-493 bpm

If a rat has a hole on the upper part of its left ear and a double notch on the end of its right ear, the rat's identification number would be:

18

Which route of administration of medication can result in lameness or self-mutilation in rats and mice?

Intramuscular

What is the average daily feed consumption of mice (per the text not the 8.1 chart)?

12-18 g

The secretions of which gland are often referred to as red tears?

Harderian gland

What is the average lifespan of a mouse?

12-36 months

What is the average respiratory rate of mice?

91-216 bpm

________ ________, and some life stages of Taenia species. V. nana are capable of infecting humans.

Hymenolepis diminuta

The gestation period for a mouse is:

19-21 days.

Rats have a large store of brown fat around the neck and scapulae that provides 10 times the energy of other types of fat. What is this tissue called?

Hibernation tissue

When delivering a medication orally, care must be taken to avoid rotating the gavage needle to prevent:

rupturing the esophagus.

The most common neoplasia in rats is:

Fibroadenoma

Which respiratory infection is often called snuffles and is the most common bacterial infection in rabbits?

Pasteurellosis

The large ears of rabbits are useful in:

thermoregulation.

The second pair of incisors in rabbits is referred to as:

peg teeth.

Which ectoparasite causes nonpruritic alopecia on the back of the rabbit?

Which disease is caused by a spirochete and is also called vent disease and can be transmitted venereally?

Treponematosis

The best vessel to use for intravenous injections in rabbits is the:

marginal ear vein.

The genus name for the rabbit used in biomedical research is:

Oryctolagus.

The option for rabbit restraint when performing an invasive or painful procedure would be:

a restraint box

Ovulation occurs approximately how many hours after coitus?

10

Because rabbits harbor a number of bacterial and viral agents without showing symptoms, researchers must often use which type of rabbit to avoid inducing variables into the study?

Specific pathogen free

Does are:

induced ovulators.

What type of crystals are normally found in rabbit urine? Choose all that apply.

Ammonium magnesium phosphate & Calcium carbonate

Which bacterial infection is primarily seen in young animals? Clinical signs vary from constipation to watery diarrhea.

Mucoid enteropathy

Which location is reserved for the tattoo for rabbits registered with the American Rabbit Breeders Association (ARBA)?

Right ear

The ideal temperature range for indoor rabbits is:

62-70° F

Which condition can be painful and may cause the animal to be reluctant to move? It can be prevented by using solid-bottom cages and regular cage cleaning.

Pododermatitis

Which condition is commonly called the slobbers and is a result of chronic drooling caused by malocclusion in rabbits?

Moist dermatitis

Which ectoparasite lives in the epidermis of the ear canal and completes its entire life cycle on the host?

Psoroptes cuniculi

Rabbits have which unique structure in the intestinal tract that has attached lymphoid tissue?

Two pairs of upper incisors

Rabbits were originally classified in the order of Rodentia but due to this physiologic difference were reclassified into their own order. What was this physiologic difference?

Two pairs of upper incisors

When administering an intramuscular injection in rabbits, which muscle groups are used?

Epaxial and/or quadriceps

Rabbit gestation is 29-35 days.

truee

The act of parturition in rabbits is referred to as:

kindling

The most common breed of rabbit used in biomedical research is the:

New Zealand white

Rabbit teeth have open roots and continue to grow throughout the animals' life. What is the term to describe this type of teeth?

Hypsodontic

What is the normal physiology value for a heart rate in rabbits?

180-250 bpm

In the picture below is the rabbit male or female?

female

Which zoonotic disease is characterized by sudden death or abortions in does?

Listeriosis