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Phospholipid bilayer
Consists of phospholipids arranged in two layers with exterior facing hydrophilic polar heads and interior hydrophobic, non-polar tails.
Selective permeability
The ability of a cell membrane to regulate which substances can enter or leave the cell, allowing some molecules through while blocking others. (Lipids and small nonpolar molecules ex: O2 and CO2
Phospholipids are
Selective permeability
Transmembrane proteins
integral membrane protein that spans the entire lipid bilayer, typically using hydrophobic. Functions in transport, signaling, adhesion, or enzymatic activity. They are embedded in phospholipid bilayer
Proteins
Are important for function of cell membrane (1.Transport, 2. Enzymes, 3. Cell surface receptors, 4. Cell surface identity marker, 5. cell to cell adhesion, 6. Attachment to the cytoskeleton, 7. Affect membrane structure)
Transporter
Enzyme
Cell surface receptor
Cell surface identity marker
Cell-to-cell adhesion
attachment to the cytoskeleton
Transport proteins
allows for the movement of polar molecules into/ out of the cell (Are selectively permeable)
Enzymatic proteins
Allow the cell to perform certain, specific functions internally
Receptor proteins
Bind external chemical singals to trigger internal action (Shape specific)
Cell surface markers
Molecules, typically proteins or carbohydrates, that are embedded in or attached to the outer layer of the cell membrane. (Identification as recognized or foreign, characteristic of each cell type)
Cell-cell adhesion proteins
Enable cells to bind to each other or to the Extracellular matrix, forming the structural and signaling basis of tissues.
Order of the cell membrane
Phospholipids, 2. transmembrane proteins, 3. Interior protein network 4. Cell surface markers
Passive transport
movement of substances across a cell membrane from high to low concentration without using cellular energy (ATP), and it includes diffusion, facilitated diffusion, osmosis and filtration
Active transport
Energy-requiring process in which cells use ATP to move molecules, or ions across membranes from low to high concentration (EX: Sodium potassium pump)
Passive transport properties
Simple diffusion: NONE, Facilitated diffusion: Channels proteins, osmosis, carrier proteins
Active transport properties:
(EX: h+ pumps & Sodium potassium pump) Secondary active transport: Symport, antiport. Endocytosis, exocytosis
Diiffusion
Passion movement of molecules or particles from a region of higher concentration to a region of lower concentration, continuing until equilibrium is reached.
Simple diffusion
Moves freely through cell membrane (ex: gases)
Facilitated diffusion
A form of passive transportation in which membrane proteins move particles across a membrane down concentration gradient
Proteins that accomplish facilitated diffusion
Carrier, channel
Carrier proteins
Bind a single molecule at a time (ex: glucose and amino acids)
Channel proteins
Allow for the passage of ions and water (Ion channels - ions, Aquaporins - water)
Osmosis
The diffusion of water across a semipermeable membrane from high to low concentration
Hypertonic examples
High solute outside, cellsize shrinks
Hypotonic examples
Low solute outside, cell size swells
Isotonic examples
Equal solute outside, cell size stays the same`
Hypertonic
Solution or environment with a higher solute concentration than another
Hypotonic
Solution with a lower solute concentration than another solution, causing water to move into cells, or a muscle with lower resting tone
isotonic
solution that has the same solute concentration as the fluid inside a cell; results in no net movement of water across the cell membrane
Secondary Active transport
Uses energy produced from passive transport to fuel other molecules to move against their concentration gradient
Symport
The transported solute moves in the same direction as the gradient of the driving ion
Antiport
The transported solute moves in the direction opposite from the gradient of the driving ion
Exocytosis
Cells use vesicle to transport fluids and large particles out of the cell
Endocytosis
Cell engulfs fluids and large molecules
Types of membrane transport
passive, active