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When does anaerobic respiration occur?
when oxygen is not available
Why does the electron transport chain stop when oxygen is not present?
oxygen is not present to be the final electron acceptor
O2 + 4H+ —> H2O does not occur
H+ accumulates in the matrix
ATP synthase does not turn as often due to reduced proton-motive force
NADH and FADH2 build up
Krebs and link reaction reduce
Can glycolysis occur without oxygen?
Yes. It can produce ATP without oxygen but only if NAD is replenished.
What are the two pathways to reoxidise NAD in eukaryotes?
Lactate fermentation
Alcoholic fermentation
How do animals reoxidise NAD in the absence of oxygen?
Lactate fermentation
How do fungi and some plant cell reoxidise NAD in the absence of oxygen?
Alcoholic fermentation
In what situations is lactate fermentation used in animals?
fight or flight reactions
very high intensity exercise
What happens in lactate fermentation?
pyruvate acts as the hydrogen acceptor
it accepts the hydrogen atom from NADH
What is the enzyme which catalyses lactate fermentation?
lactate dehydrogenase
What is the hydrogen acceptor in lactate fermentation?
pyruvate
What are the products of lactate fermentation?
lactate
NAD
What is pyruvate reduced to in lactate fermentation?
lactate
What happens to the lactate produced in lactate fermentation?
carried away by blood to the liver
oxygen is used to convert lactate back to glucose
can then be used again in respiration
What does lactate dissolve to form in the blood + what is the impact?
dissolves to form lactic acid
reduces the pH in tissues
toxic to cells
What happens in alcoholic fermentation?
pyruvate is decarboxylated to produce ethanal
ethanal accepts a H atom from NADH and becomes ethanol
regenerated NAD can be used again in glycolysis
What enzyme catalyses the decarboxylation of pyruvate in alcoholic fermentation?
pyruvate decarboxylase
What is the hydrogen acceptor in alcoholic fermentation?
ethanal