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Digestive System
the organs and glands associated with the ingestion and digestion of food
Step 1 of digestion system
Chewing breaks up food and mixes it with saliva into nutrients in preparation of absorption
Step 2 of Digestive System
Absorption- the uptake of nutrients by cells of the small intestine for transport into either the blood or lymph
Bolus
A term used to describe food after it has been chewed and mixed with saliva
Gastric Juice
A digestive fluid secreted by the stomach digests protein
What is the enzyme that starts the breakdown of starch in the mouth?
Salivary amylase
What connects the mouth to the stomach?
esophagus
Enzymes involved in the digestion of food
Lipase- made in the pancreas breaks down fats
Amylase-made in the mouth and pancreas breaks down complex carbohydrates
Protease- made in the pancreas breaks down proteins
What are the accessory organs of the digestive system?
Gallbladder, Pancreas, and Liver
Where does most digestion and absorption occur?
Small intestine
Microvilli and villi are found in the
Small intestine
What is produces in the pancreas to regulate blood glucose
Insulin and glucagon
What is the main function of the large intestine?
store undigested food material, absorb water, short-chain fatty acids, and electrolytes
What are the three segments of the small intestine?
Duodenum, jejunum, and illeum
What vitamins does the gastrointestinal microbe produce?
B6, B12, and K
Segmentation
Contraction of circular muscles in small intestine and stomach
Carbohydrates
Broken down into glucose to provide energy
Preferred energy source for nerve cells
Source of Carbohydrates
All plant foods- whole grains, vegetables, legumes, fruits, and milk
Monosaccharides
Single sugar molecules (simple sugars)
3- Glucose, fructose, and galactose
Glucose
Essential energy source, part of every disaccharide, most abundant CHO
Characteristics of Fructose
Sweetest of sugars, same formula as glucose but structured differently
-Monosaccharide
Disaccharides
pair of two monosaccharides
-Maltose, sucrose, and lactose
Characteristics of Sucrose
glucose and Fructose together, naturally in fruits and honey. Sweetest of disaccharides. Found in brown, white, and powdered sugars.
Composition of Sucrose
Glucose + Fructose
Maltose
found in seeds and alcoholic beverages
Maltose composition
glucose + glucose
Characteristics of Lactose
Principal carbohydrate of milk that contributes half of the energy (kcals) provided by fat-free milk.
-Disaccharide
Composition of Lactose
Glucose + Galactose
Polysaccharides
Carbohydrates that are made up of more than two monosaccharides
Starch
A storage polysaccharide in plants consisting entirely of glucose.
-Digestible polysaccharide
Fiber
Structural part of plants. INDIGESTIBLE
What are the two types of dietary fibers?
Soluble and insoluble
Soluble fiber
Can dissolve in a given solvent
Insoluble fiber
cannot dissolve in a given solvent
Pancreatic amylase
An enzyme secreted by the pancreas into the small intestine that digests any remaining starch into maltose
Where is the storage form of glucose stored?
In the liver as glycogen
Function of Insulin
Moves glycose from blood into cells lower blood glucose levels
Source of Insulin
Pancreas
When blood glucose rises above normal
Insulin can signal the cells to take in glucose for energy
Hormone which helps to regulate extremely low blood sugar/glucose
glucagon
Characteristics of Hypoglycemia (low blood sugar)
weakness, rapid heartbeat, sweating, anxiety, hunger, and trembling
Characteristics of Hypoglycemia (low blood sugar)
weakness, rapid heartbeat, sweating, anxiety, hunger, and trembling
Benefits of lower glycemic index
Less fluctuations in blood glucose
-Risk reduction for heart disease and colon cancer
Foods with lower glycemic index
beans, fresh vegetables, whole wheat
Foods with higher glycemic index
dry cereal, white bread, candy
Type 1 diabetes
Form of diabetes that usually develops during childhood or adolescence and is characterized by a severe deficiency of insulin, leading to high blood glucose levels.
Type 2 Diabetes
Form of Diabetes that develops especially in adults and most often obese individuals and that is chacterized by high blood glucose resulting from impaired insulin utilization coupled with the body’s inability to compensate with increased insulin production.
Most common form of diabetes
Type 2 diabetes
Lower-card diet facts
Metabolism similar to fasting, uses glycogen stored first, uring monitoring, and ketosis
DRI Carbohydrates
45%-65% of daily calories
RDA of carbohydrates
130 grams per day
DRI Fiber
14 grams per 1000 kcals
25g/day for women
28g/day for men
How many g of fiber do vegetables contain?
2 to 3 g per serving
How many g of fiber in fruits
2
How many g of fiber do legumes contain
abt 6-8 g
Alcohol is linked to increase risk for:
Breast cancer
Hypertension
hemorrhagic stroke
NOTE: Alc provides energy not nutrients
How much energy per day do lipids provide?
9kcal/g
Lipids
insoluble in water. Energy-rich organic compounds, such as fats, oils, and waxes, that are made of carbon, hydrogen, and oxygen.
3- triglycerides, phospholipids, and sterols
Dietary lipids are found in what form?
Triglycerides
Triglycerides are made up of
3 fatty acids + glycerol
Most lipids you can consume are…
triglycerides
Liquid v. solid room temp fat
Degree of unsaturated influences firmness
Unsaturated = lipid
Saturated = solid
Monounsaturated fats
one double bond- lacks hydrogen atom on carbon
polyunsaturated fats
one double bond- lacks hydrogen atom on carbon
Hydrogenation
more than one double bond- lacking associated hydrogen atoms on carbons
Main site for fat hydrolysis
Small intestine
Phospholipids
Soluble in fat and water, emulsifies in food industry, having a polar, hydrophilic head and non polar, hydrophobic tail
High-density lipoproteins (HDL’s)
Made in liver, to remove cholesterol from the cells and carry back to the liver for recycling, composed mostly of proteins
Low-density lipoproteins (LDL’s)
Circulated throughout the body. It takes triglycerides, cholesterol, and phospholipid to use for energy. Makes hormones/ compounds, or build new membranes.
How much energy does fat provide while at rest
60%
Daily energy intake from fat AMDR
20 to 35%
What differentiates amino acids from each other?
the 4th attachment site distinguishes each amino acid from the others
Bonding of two amino acids?
Peptide bonds connect the two
Proteins contains
carbon, hydrogen, oxygen, nitrogen
Protein denaturation
Breakdown of proteins that permanently alters their biological activity; it can be caused by excessive heat
building blocks of proteins
amino acids (20 types)
4 types of lipoproteins
The four main classes of lipoproteins are chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL)
Highest Quality protein
Animal protein
Enzymes
Proteins that speed up chemical reactions act as catalyst
How many nonessential amino acids are there?
11- Can be made by the body
Essential amino acids
Histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine
How many essential amino acids are there?
9: must be obtained from diet
Protein synthesis
Refers to the fact that everyone is different due to differences in proteins. Differences are determined by amino acid sequences of proteins which are determined.
Protein Structure: Primary
sequence of amino acids
Protein Structure: Secondary
Polypeptide chain that forms twists and folds/hydrogen bonds between amine and carboxyl groups
Protein structure: Tertiary
Complex shapes
quaternary structure
the fourth level of protein structure; the shape resulting from the association of two or more polypeptide subunits
Negative Nitrigen Balance
Body degrades more proteins than synthesizes (starvation)
Positive Nitrogen Balance
body synthesizes more proteins than degrades (GROWTH)
Protein turnover
in each cells