Wk 6 full

Warfarin

Coumadin

Anticoagulant (Vit. K antagonist) use

Prevention of VTE or PE, useful for those w/ heart valves

Anticoagulant (Vit. K antagonist) black box warnings

Major/fatal bleeding

Anticoagulant (Vit. K antagonist) contraindications

Pregnancy

Anticoagulant (Vit. K antagonist) side effects/warnings

Bleeding/bruising, skin necrosis/gangrene, purple toe syndrome, goal INR 2-3 for most indications

Anticoagulant (Vit. K antagonist) overdose antidote

Vitamin K

Clopidogrel

Plavix

Platelet aggregation inhibitor use

Myocardial infarction, Thrombosis prevention

Platelet aggregation inhibitor black box warnings

Clopidogrel = prodrug = poor metabolizes of CYP2C19

Platelet aggregation inhibitor contraindications

Hypersensitivity, active bleeding

Platelet aggregation inhibitor side effects/warnings

Bleed risk, stop 5 days prior to surgery, do not use w/ Omeprazole or Esomeprazole

Apixaban

Eliquis

Rivaroxaban

Xarelto

Anticoagulant use

Prevetion/treatment of DVT or PE

Anticoagulants (Factor Xa inhibitors) black box warnings

All patients receiving epidural/spinal at risk for hematoma and paralysis, premature discontinuation inc. thrombotic risk

Anticoagulants (Factor Xa inhibitors) contraindications

Active bleeding

Anticoagulants (Factor Xa inhibitors) side effects/warnings

Bleeding, not rec. for pt w/ mechanical heart valves, discontinue 24-48hrs before surgery

Anticoagulants (Factor Xa inhibitors) overdose antidote

Andexanet alfa (Andexxa)

Rapid acting insulins

Lispro, Aspart, Glulisine

Short acting insulins

Regular insulin

Intermediate acting insulin

insulin NPH

Long acting insulins

Insulin glargine (Lantus), Insulin detemir (Levemir)

Insulin degludec

Tresiba

Insulin glargine

Lantus

Insulin detemir

Levemir

Insulin lispro

Humalog

Insulin aspart

Novolog

Inhaled insulin

Afrezza

Insulin uses

Type 1 and 2 DM

Insulin contraindications

Hypersensitivity, inhaled insulin contraindicated in asthma/COPD (acute bronchospasm)

Insulin side effects/warnings

Hypoglycemia (rule of 15 helps), wgt gain, store unopened insulin in fridge, dispose needles in sharps container