PSYC 110 HEAT AND COOLING, MECHANORECEPTORS

TRPV4

• Warm (~27-34^o) active a lot during spring

TRPV3

 (~31-39^o) active a lot during spring

TRPV1

• Hot  (>43^o). Also activated by capsaicin, the active ingredient of hot chili peppers --> summer day, also in taste buds where it sense capsaicin

TRPV2

 Painfully hot  (>52^o) --> touch a stove, tissue damage

TRPM8

moderate cold (<25 deg C) - the 'menthol channel' --> activate by cough drop

TRPA1

<18deg C --> for ex if a bear is hibernating and temp gets too low these receptors will wake up the bear

Ruffini corpuscles

vibration sensitive, large receptive fields, slow adapting, glabrous

Pacinian corpuscles

• detects mechanical stimuli, especially vibrations, large receptive fields, fast adapting, hairy, glabrous

Merkel’s Disks

 touch sensitive, small receptive fields, slow adapting, hairy, glabrous

Meisner

detecting light touch, small receptive fields, fast adapting, glabrous