Lecture 8: Issues with the current drug development paradigm

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Last updated 3:31 PM on 9/29/26
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4 Terms

1
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What is Simcyp?

The program incorporates data on

  • patient demographics

  • disease states

  • anatomical, physiological and biochemical variables

  • in vitro drug metabolism


2
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Composite drugs

  • The drug

  • Diagnostic kit (e.g. genotyping)

  • Personalized medicine framework

  • Surrogate marker development


3
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What are 3 other technological advances that may impact drug development?

  • Human Genome Organisation / Human Proteome Organization

  • Surrogate/biomarker development

  • Genetic diagnostics (personalised medicine)


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