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Vitamin K
necessary for synthesis of blood clotting factors
Vitamin K antagonists
disrupt synthesis of blood clotting factors and coagulation
Vitamin K antagonists examples
Warfarin and dicoumeral
Function of cardiovascular system
transport
Components of the cardiovascular system
Heart, arteries, and veins
Artereis
transport blood away from the heart to tissues
Veins
return blood to the heart from tissues
Heart parts
base, apex, pericardium, heart wall
Heart shape
cone shape
Base of heart
the end attached to other structures
Apex of heart
free end of heart
Pericardium
protective membrane surrounding the heart
Layers of pericardium
parietal pericardium, pericardial cavity, visceral pericardium
Parietal pericardium
outer layer of pericardium
Parietal pericardium made of
dense irregular connective tissue
Pericardial cavity location
space between parietal and visceral pericardium
Pericardial cavity contains
pericardial fluid
Visceral pericardium made of
composed of simple squamous epithelial tissue
Layers of heart wall
Epicardium, myocardium, endocardium
Epicardium
outer layer of heart wall
Epicardium is composed of
composed of simple squamous epithelium
Myocardium
middle layer of heart wall
Myocardium made of
cardiac muscle, thickest layer
Endocardium
inner layer of heart wall
Endocardium made of
composed of simple squamous epithelium
Heart is divided into
left and right halves, each having 2 chambers
Two chambers of heart
atrium and ventricle
Atrium
receives blood from veins
Ventricle
pumps blood into arteries
Ventricular septum
layer of myocardium between the 2 ventricles
Atrioventricular valves
separates the atria from venricles
Types of atrioventricular valves
tricuspid valve and mitral valve
Tricuspid valve
separates right atrium from right ventricle
Mitral valve
separates left atrium from left ventricle
Semilunar valves
separates ventricles from arteries
Types of semilunar valves
pulmonary valve and aortic valve
Pulmonary valve
separates right ventricle from pulmonary artery/trunk
Aortic valve
separates left ventricle from aorta
Blood flow through right side of heart
vena cavae empty into right atrium
blood flow through the tricuspid valve into right ventricle
blood flows through pulmonary valve into pulmonary trunk
Blood flow through left side of heart
pulmonary veins empty into left atrium
blood flows through mitral valve into left ventricle
blood flows through aortic valve into aorta
Blood vessel lining is
continuous with endocardium and made of simple squamous epithelium
Arteries branch into
arterioles
Arterioles branch into
capillaries
Capillaries branch into
tissues
Cappilaries merge to form
venules
Venules merge to form
veins
Circulatory systems
pulmonary circulation, systemic circulation, coronary circulation
Pulmonary circulation flow
circulates blood from right side of heart to lungs to left side of heart
Pulmonary circulation types of hemoglobin
carbaminohemoglobin leaves heart, oxyhemoglobin returns
Systemic circulation flow
circulates blood from left side of heart to everywhere in body except lungs to right side of heart
Systemic circulation types of hemoglobin
oxyhemoglobin leaves heart, carbaminohemoglobin returns
Coronary circulation flow
circulates blood from left side of heart to the tissue of heart to the right side of heart
Portal system
a vein returning blood to the heart reforms a capillary bed before returning to the heart
Types of portal systems
Hepatic portal system and hypophyseal portal system
Hepatic portal system
blood leaving organs of digestive tract enters the hepatic portal vein for transport to liver where capillaries reform before transporting blood to heart
Hypophyseal portal system
blood leaving hypothalamus enters capillaries in anterior pituitary before returning to heart
Cardiac muscle fibers characteristics
short cell connected by intercalated discs, striated, involuntary, do not require neural stimulation
Cardiac muscle fibers being striated means
they have sarcomeres that contract the same way as skeletal muscle
CONTINUE
Sinoatrial (SA) node found in
right atrium
Sinoatrial (SA) node made of
pacemaker cells
Pacemaker cells made of
specialized cardiac muscle fibers
Pacemaker cells
spontaneously generate action potential in a rhythmical manner
Action potential in the SA node are transmitted
through the right and left atrium through intercalated discs
Action potential from SA node to atriums causes
contraction of atria
Atrioventricular (AV) node location
right atrium
SA node sends action potential to
Atrioventricular (AV) node
Atrioventricular (AV) node
delays transmission of action potential
AV node sends action potential to
Bundle of His
Bundle of His
delays transmission of action potential
Bundle of His sends action potential to
Right and left bundle branches along the interventricular septum
Bundle branches of interventricular septum branch into
Purkinje fibers
Purkinje fibers
transmit action potential throughout ventricles
Action potential throughout ventricles results in
ventricles contracting
Cardiac cycle definition
the events that occur during one complete heartbeat
Cardiac cycle
diastole and systole
Diastole
relaxation of the ventricles and ventricles fill with blood
Diastole sound
Dub
Systole
contraction of the ventricles and ventricles empty
Systole sound
Lub
Heart rate definition
frequency of cardiac cycle per minute
Blood pressure definition
force exerted on a blood vessel wall
Blood pressure in arteries
high
Blood pressure in capillaries
moderate
Blood pressure in veins
low
Blood pressure gradient
returns blood to heart
Measure blood pressure by taking
systolic blood pressure / diastolic blood pressure
Lymphatic system funtions
fluid balance, lipid absorption, defense
Fluid balance lymphatic system function
returns fluid lost from the blood back to the blood
Lipid absorption lymphatic system function
lipids enter lymphatic system after absorption for distribution throughout body
Defense lymphatic system function
lymphocytes develop and are activated
Lymphatic system componants
lymphatic capillaries and vessels, lymph nodes, thymus, bursa of Fabricius, spleen
Lymphatic capillaries and vessels
transport lymph
Lymph nodes
activate lymphocyes
Thymus
where T lymphocyte development occurs
Bursa of fabricius
where B lymphocyte development occurs in birds
Spleen lymphatic system component
Has red and white pulp
Red pulp of spleen
removal of RBCs, reservoir for RBCs
White pulp of spleen
activation of lymphocytes