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Disease
any deviation form or interruption of the normal structure/function of a body part, organ, or system
infection
establishment & growth of a microorganism on or in a host, resulting in injury to the host; caused by pathogenic microorganism
pathogens have three (3) functions
multiply in large numbers & cause an obstruction; cause tissue damage; secrete organic substances called exotoxins
exotoxins caused side effects
high temps, nausea, vomiting, seizures
the six (6) stages of infectious disease development in order?
encounter; entry; spread; multiplication; damage; outcome
four factors that make up the chain of infection?
host, infectious microorganism, mode of transmission, and reservoir
the four infectious agents
bacteria, viruses, fungi, & parasitic protozoa
what is a reservoir?
a place where an infectious organism can survive and from which it can spread
what happens during encounter?
the infectious organism comes into contact with the host
what happens during entry?
the organism gains access through a portal of entry (nose, mouth, eye, wound)
a microbe attaches to a surface & releases toxins without crossing the epithelial barrier. what type of entry is that?
ingression
a microbe crosses the epithelial barrier through a cut. what type of entry is that?
penetration
what is the difference between spread & multiplication?
spread MOVES microbes to other sites; multiplication INCREASES their numbers
what is the incubation period?
the interval before the infection becomes apparent
how can the host’s response contribute to tissue damage?
inflammation & immune responses can damage host tissue
what are 3 possible outcomes after exposure to an infectious agent?
the host clears the agent, develops disease, or coexists with it
what is colonization?
the presence of microbes without disease
what distinguishes infectious disease from colonization?
infectious disease involves harm to the host
what kind of cells are bacteria?
single celled prokaryotes
what shape are cocci?
round or spherical
what shape are bacilli ?
rod shaped
what technique helps classify bacteria by their staining reaction?
gram staining
what is bacterial endospore?
a dormant, resistant survival form produced by certain bacteria
are viruses cells?
viruses are acellular infectious agents
what kind of genetic material does a virus carry?
DNA or RNA
what is a viral capsid?
the protein coat surrounding the viral genome
what is a virion?
a complete virus particle
why does a virus need a living host cell?
it uses the host cell’s machinery to replicate
what does dimorphic mean for fungi?
able to grow in two forms, such as yeast & mold
what are the 4 categories of fungal infection?
superficial, cutaneous, subcutaneous, & systemic
what kind of cells are protozoa?
single celled eukaryotes
what is a protozoan cyst?
a protective stage that can help some protozoa survive outside a host
what are two (2) protozoan infections?
malaria & trichomoniasis
a contaminated X-ray image receptor is called a what?
fomite
a mosquito that transmits malaria is called what?
vector
a patients own skin bacteria enters a wound. is this endogenous or exogenous?
endogenous
a microorganism comes from a contaminated object outside the body. is this endogenous or exogenous?
exogenous
what is healthcare-associated infection (HAI)?
an infection acquired in connection with healthcare
what does nosocomial mean?
acquired in a hospital
what does iatrogenic mean?
caused by a healthcare intervention
a UTI is linked to a foley catheter placed during hospital stay, what three (3) infection lables can apply?
what are four (4) possible sources of HAI's?
healthcare personnel, patient flora, contaminated equipment or surroundings, & invasive devices
what organ does HBV primarily affect?
the liver
which immune cells does HIV target?
CD4 T cells
is intact skin a mechanical, chemical, or cellular defense?
mechanical
is stomach acid a mechanical, chemical or cellular defense?
chemical
what do phagocytes do?
engulf foreign particles & microbes as part of cellular defense
how can normal flora help protect the host?
they compete with pathogens for space & resources
what kind of immunity does vaccination stimulate?
active immunity
what is the difference between bacteriostatic & bactericidal?
bacteriostatic inhibits bacterial growth; bactericidal kills susceptible bacteria
what is the goal of medical asepsis?
reduce the number & spread of microorganisms
what is the goal of surgical asepsis?
maintain sterility & prevent contamination
where are disinfectants & antiseptics used?
disinfectants are used on objects; antiseptics are used on living tissue
which process eliminates viable microorganisms, including bacterial endospores?
sterilization
what does an autoclave use?
steam under pressure
what does pasteurization do?
it reduces microbes without sterilizing the product
who recieves standard precautions?
every patient
how do transmission-based precautions relate to standard precautions?
they are added to standard precautions when indicated
when should hand hygine occur relative to putting on & removing gloves?
before putting gloves on & after removing gloves
where do sharps go?
in a designated puncture-resistant sharps container
what is the difference between direct & indirect contact transmission?
direct contact involves touching the person; indirect contact involves touching a contaminated object
which precautions pair with gown & gloves?
contact precautions
which precautions pair with a medical mask?
droplet precautions
which precautions pair with a negative-pressure room & repiratory protection for staff?
airborne precautions
which precautions are used for pulmonary TB?
airborne precautions
which precautions are used for rubella?
droplet precautions
which precautions are used for rubeola (measles) in the guide?
airborne precautions
which two transmission-based precautions are used for chickenpox?
airborne & contact precautions
which precaution category is associated with MRSA & C. difficile in the guide?
contact precautions
why does the assistant avoid touching the outside of the cassette bag during a portable x-ray?
the outside may be contaminated, the handoff keeps that surface away from the clean cassette
what is the main purpose of aseptic technique?
protect the patient from infection & prevent the spread of harmful microorganisms
what does sterile mean?
free of living microorganisms
what is a sterile field?
an area considered free of viable microorganisms that can receive sterile supplies
what is the difference between surgical & medical asepsis?
surgical uses sterile technique; medical reduces microorganisms & their spread
what is the difference between cleaning, sanitizing, & disinfecting?
cleaning removes dirt; sanitizing reduces microbial numbers to safe levels; & disinfecting removes most microorganisms, with highly resistant forms potentially remaining
which imaging procedures can require sterile technique?
angiography, arthrography, hysterosalpingography, myelography, & biopsies
what does pyelography examine?
the spinal canal, spinal cord, & nerve roots using an injected contrast agent & x-rays
what is fenestrated drape?
a drape with an opening that exposes the procedure site
what does subungual mean?
beneath a fingernail or toenail
what is purulent drainage?
drainage containing pus
what is serous drainage?
thin, watery, usually clear or pale-yellow fluid
how do you apply alcohol based hand sanitizer?
apply to one palm, rub hands together, & cover all hand & finger surfaces until dry
before opening a sterile package you should inspect what?
package integrity, cleanliness, dryness, evidence of prior opening, & expiration date
a sterile package is damp or has water stains, how should it be handled?
as unsterile
a sterile package has a tear or has already been opened, how should it be treated?
as unsterile
what is the opening order for a wrapped sterile package on a table?
open the far flap away from you, the side flaps, & then the near flap towards you
why is the far flap opened first?
it allows the wrapper to open while reducing the need to reach across sterile contents
what part of a sterile package margin is considered unsterile?
the outer 1-inch boarder
a sleeve touches the inside of a sterile wrapper, what does that mean for the pack & contents?
considered unsterile & must be replaced
how far above the sterile field are supplies dropped from a held package?
approximately 6 inches, gently & at a slight angle
should an unsterile person reach across a sterile field?
no, it can contaminate it
should sterile supplies be flipped onto a sterile field?
no, add them gently using proper technique
an opened sterile field is left unattended, how is it treated?
as contaminated
sterile supplies fall below waist level, how is it treated?
as contaminated
why should a sterile field be established clost to the time of use?
to limit exposure & opportunities for contamination
what should you do if you doubt an item’s sterility?
treat it as unsterile
can a person wearing sterile gloves touch an unsterile object & remain sterile?
no, contact contaminates the glove
why must sterile materials stay dry?
moisture can allow microorganisms to move through the material
fluid soaks through a drape from a nonsterile surface, what happened?
the sterile barrier has been compromised by moisture
when pouring sterile solution, which parts of the bottle are treated as contaminated?
the outside of the bottle