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Depressive disorders
Sustained low mood and changes in thinking, behaviour and emotion that can interfere with relationships, study and work
DSM-5 depressive-disorder group
1. Major depressive disorder (MDD)
2. Persistent depressive disorder (PDD/dysthymia)
3. Disruptive mood dysregulation disorder
4. Premenstrual dysphoric disorder
5. Substance/medical-condition-related forms
Major depressive disorder
· At least 5 symptoms within the same 2-week period, including depressed mood OR loss of interest/pleasure
- Symptoms occur most of the day, nearly every day and cause distress or impairment
· Symptoms: appetite change, sleep disturbance, fatigue, worthlessness/excessive guilt, poor concentration, recurrent thoughts of suicide
Diathesis–stress model
Inherited vulnerability interacts with stressful life events to increase risk
· Vulnerability does not mean depression is inevitable
Cognitive-behavioural model (Beck)
Automatic negative thoughts and biased beliefs influence feelings and actions
· Withdrawal then reduces rewarding experiences, reinforcing low mood

Beck’s negative cognition triad
Negative beliefs about self, world/environment and future
· Same event, different interpretation → different emotion
Mental filter
Focus on negative info while overlooking positives
Personalisation / self-blame
Take responsibility for failures but discount successes
Mindreading
Assume others dislike or judge you without evidence
Catastrophising
Predict the worst outcome
Black-and-white thinking
View events as total success or failure
Emotional reasoning
Treat feelings as proof
Overgeneralisation
Use one setback to draw a broad negative conclusion
Depressive maintenance cycle
Stressful event → automatic negative belief → low mood → withdrawal / less activity → fewer positive experiences → stronger negative belief and mood
· Behavioural consequences: reduced motivation, stopping enjoyable activities or exercise, social isolation, difficulties with study/work - these maintain depression
· Thoughts alone don’t cause depression, biological predisposition and stressful events also matter
Persistent depressive disorder (PDD)
· Depressed mood for ≥2 years in adults (≥1 year in children/adolescents)
· Most of the day and on more days than not
· ≥2 symptoms of appetite, sleep, energy, self-esteem, concentration or hopelessness symptoms
· Symptom-free intervals do not exceed two months
· Symptoms are often less intense than MDD but more enduring
- MDD and PDD can co-occur
Bipolar disorders
Episodes of elevated/irritable mood and increased energy or activity, with depressive episodes also important
· Strong biological/genetic contribution; episodes and severity vary

Manic episode
· Abnormally elevated, expansive or irritable mood AND increased activity/energy for ≥1 week
· Most of the day nearly every day
· ≥3 associated symptoms (≥4 if mood only irritable), with marked impairment
· Symptoms: grandiosity, decreased need for sleep, pressured speech, racing thoughts, distractibility, increased goal-directed activity or agitation, risky activities
· May feel euphoric or productive initially symptoms can have serious consequences
Mania vs hypomania vs bipolar subtypes

Clinical significance and management
· Diagnosis requires attention to severity, duration, impairment and whether symptoms fit depression or mania
- Elevated mood alone does not establish bipolar disorder
· Combining medical treatment (e.g. lithium) with psychological support to manage current episodes and prevent recurrence
Positive symptoms
Presence of unusual experiences/behaviours
Negative symptoms
Reduction or absence of normal functioning
Psychotic symptoms:
• Delusions
• Hallucinations
• Disorganised thinking/speech
• Disorganised or abnormal motor behaviour
• Negative symptoms
Schizophrenia
Delusions
Strongly held false beliefs despite contradictory evidence; may involve confirmation bias.
• Types: persecution, influence and grandeur
• Positive symptom
Hallucinations
Perception without an external stimulus
• Often auditory (critical or commanding voices)
• Positive symptom
Disorganised thinking/speech
Disrupted thought processes reflected in speech
• Loose associations: jumping between unrelated ideas
• Clang associations: linking words by sound rather than meaning
• Paralogic: reasoning appears logical but is seriously flawed
• Speech may be chaotic or nonsensical
• Positive symptom
Disorganised motor behaviour
Inappropriate or unpredictable behaviour, agitation, silliness and difficulty with daily activities
• Positive symptom
Catatonic behaviour
Markedly reduced responsiveness, resistance to instructions, rigid postures or mutism
• May involve unusual or exaggerated motor activity
• Positive symptom
Reduced emotional expression
Limited facial expression, eye contact and gestures
• Negative symptom
Avolition
Reduced motivation/initiation of goal-directed activity
• Negative symptom
Alogia
Reduced speech
• Negative symptom
Anhedonia
Reduced ability to experience pleasure
• Negative symptom
Associated problems with schizophrenia
• Sleep disturbance, depression/anxiety, substance use
• Cognitive difficulties, poor insight and motor deficits
• Elevated suicide risk (5–6% die by suicide; 20–30% attempt)
• Violence may occur but is NOT characteristic of most people with schizophrenia
Course and phases of schizophrenia
• Prodromal: early changes before an active episode
• Active: prominent psychotic symptoms
• Residual/remission: active symptoms reduce, but some difficulties may persist
• Often requires long-term management
- Symptoms can relapse and remit
Historical subtypes
1. Paranoid
2. Disorganised
3. Catatonic
4. Undifferentiated
5. Residual
Vulnerability / diathesis-stress model
• Schizophrenia may develop through interaction between predisposition (vulnerability) and environmental stress
• Different combinations of vulnerability and stress may contribute to onset

Susto
• Latin American cultural concept involving fear/fright, anxiety and physical symptoms (e.g. weakness, weight loss, palpitations)
• Traditionally attributed to frightening events or supernatural influences
• Traditional healing practices may be used
Winigo
• Historically described in some Algonquian cultural contexts
• Fear of transformation into a cannibalistic supernatural being
• Depression, appetite loss, nausea and insomnia
Anorexia Nervosa
• Restriction of food intake, intense fear of weight gain and body-image disturbance
• Historically associated with Western cultural ideals, but occurs across cultures
• Not strictly a culture-bound disorder