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what are muscles?
organs that generate for to cause movement
what are the 3 types of muscle tissue?
skeletal, smooth, and cardiac
what is the dense connective tissue that surrounds and separate each muscle called?
fascia
what is the connective tissue that connects muscle together?
aponeuroses
what does the fascia blend with?
epimysium
what is epimysium?
a layer of connective tissue around each skeletal muscle
what is a fascicle?
a bundle of muscle fibers
what is the perimysium?
the connective tissue layer that surrounds each fascicle
where is the perimysium located?
it extends inward from the epimysium
what is endomysium?
connective tissue ayer that surrounds each individual muscle fiber
what are three connective tissue layers of skeletal muscle, from outermost to innermost?
epimysium→perimysium→endomysium
(TIP) remember these!! the answer will be labeled (KEY)
(KEY) EPI= entire muscle; PERI= pack/bundle (fascicle); ENDO= each individual fiber
how do you describe each muscle fiber?
single, long, cylindrical muscle cell
what is the cell membrane of a muscle fiber?
sarcolemma
what is the cytoplasm muscle cell called?
sarcoplasm; contains mitochondria and nuclei
sarcoplasm contains ______ and is active in muscle contraction?
myofibrils
thick filament in myofibrils consists of what protein?
myosin
thin filaments in myofibrils are mainly composed of what proteins?
actin, troponin, tropomyosin
the organization of these filaments produces bands called ____?
striations
myofibrils are made up of what?
sacromeres; joined end-to-end
What is made up of actin filaments and are anchored to the Z lines?
I bands (light bands)
what is made up of overlapping thick and thin filaments?
A bands (dark bands)
the H zone consists of what?
myosin filaments
where and what consists of proteins that hold myosin filaments in place?
M line
what is the term? a network of membranous channels which is the endoplasmic reticulum of a muscle cell
sarcoplasmic reticulum (SR)
the SR is associated with what?
transverse (T) tubules; invaginations of the sarcolemma
each T tubules lye between what?
2 cisternae
skeletal muscle fibers contract only when stimulated by?
motor neuron
what creates a synapse?
every skeletal muscle fiber is functionally connected to the axon of a motor neuron
how does the neuron communicate with the muscle fibers?
neurotransmitters
what is neuromuscular junction?
a synapse between a motor neuron and a muscle fiber that it regulates
what is the motor end plate?
it’s where the sarcolemma is tightly folded; contains specific receptors for the neurotransmitter
what is the gap between the membranes of the neurons and muscle fiber?
synaptic cleft
what is released into the synaptic cleft at the end of an electric pulse?
synaptic vesicles release neurotransmitters
what happens to sarcomeres during muscle contraction?
they shorten
what creates the pulling force during muscle contraction?
myosin binds to actin and pulls on it
what happens to actin and myosin during contraction?
they slide past each other, increasing their overlap
what do actin and myosin filaments do?
they slide past each other
what causes a muscle fiber to shorten?
the increased overlap between actin and myosin filaments
what happens when individual muscle fibers shorten?
the entire muscles shortens
what do filaments do?
they slide
what do myosin molecules consist of?
two twisted strands with globular heads projected outward along the strands
what do actin molecules consist of?
globular proteins arranged in twisted filaments
what are 2 proteins associated with actin molecules?
troponin and tropomyosin
what is acetylcholine?
a neurotransmitter for skeletal muscle fiber contraction
where is acetylcholine produced and released at?
its produced in the motor neuron; released into the synaptic cleft
what does sarcoplasmic reticulum release?
stored calcium
what does the motor neuron release?
Acetylcholine (ACh)
what does (ACh) bind to?
ACh receptors on the muscle fiber membrane (saecolemma)
where does the muscle impulse travel to?
across the sarcolemma and down the transverse tubules
what does the impulse cause the sarcoplasmic reticulum to release?
calcium (Ca2+)
what does calcium bind to?
troponin
what happens when calcium binds to troponin?
it moves
what happens when the binding sites are exposed?
myosin binds to actin, forming cross-bridges
what do cross-bridges do?
pull thin filaments towards the center of the sarcomere
what is the first phase of cellular respiration and occurs in the cytoplasm?
glycolysis; yields 2 ATP
what is aerobic respiration?
a complete breakdown of glucose and requires oxygen; yields 28 ATP
what is hemoglobin?
red blood cells carries oxygen to muscle tissue
what is oxygen debt?
the amount of oxygen that liver cells require to concert the accumulated lactate back into glucose
what is the leftover cellular respiration become?
heat
what is the heat used for?
to help maintain body temperature
what happens when a muscle loses its ability to contract during strenuous exercise?
fatigue
what classifies as fast fibers?
make up majority of muscle fibers; rapid movements; fatigue quickly; larger diameter; few mitochondria; powerful contractions
what classifies slow fibers?
small diameter; takes longer to reach peak; used in endurance activities; many mitochondria
what is hypertrophy?
enlargement of a muscle due to repeated exercise
what is atophy?
decrease in muscle size and strength
what is a threshold stimulus?
the minimum strength of a stimulus required to generate a impulse through the muscle fiber
what is a twitch?
response of a single muscle fiber to a single impulse
what is myogram?
a recording of an electrically stimulated muscle contraction
what is the latent period?
a brief delay between the stimulation and beginning of the contraction
summation slide 37