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Cardiac output
CO = stroke volume (SV) × heart rate (HR)
Preload
The pressure generated in the ventricles at the end of diastole and the resultant stretching of the muscle fibers
Afterload
The amount of resistance to ejection of blood from the ventricle
Contractility
The force generated by the contracting myocardium under any given condition
Creatine kinase
Enzyme found mainly in cardiac cells that is released upon cell death; Elevated levels is indicator of acute MI- peaks within 24 hrs
Troponin
Protein found in myocardium which regulates contractile process; Increase in troponin can be detected within hours and remains elevated for often as long as 3 weeks to detect recent MI damage
Echocardiogram
Measure ejection fraction
Examine size, shape, & motion of cardiac structures
Determine chamber size
Etiology of heart murmurs
Evaluating function of heart valves & ventricular wall motion
Electrocardiogram
Records the electrical activity of the heart using skin sensors called electrodes; The # & placement of electrodes depends on type of ECG needed *Most use 3 to 5 placed on limbs and chest
P wave
Atrial depolarization; Firing of the SA node, indicating atrial contraction
QRS
Ventricular depolarization; Impulse has traveled through Bundle of His, right & left bundles & has reached Purkinje fibers, indicating ventricular contraction
T wave
Ventricular repolarization (resting state)
Isoelectric line
When no electrical activity is detected the line on the graph is flat
PR interval
0.12-.20 sec
A fib
Quivering— no P waves; Big risk for clots!!
PP interval
Used to determine atrial rhythm & rate
RR interval
Used to determine ventricular rhythm and rate
ST segment
Represents early ventricular repolarization; Usually isoelectric
U wave
Thought to be Purkinje fiber repolarization; Sometimes also seen with low potassium, HTN, heart disease
QT interval
<0.40 sec; If prolonged = risk for the lethal ventricular dysrhythmia of “Torsades de Pointes”
Arrhythmias
Disorders of the electrical impulses within the heart that cause disturbances of heart rate, heart rhythm, or both
Athersclerosis
Deposition of plaque on walls
Myoglobin
Heme protein that helps transport O2, also found in skeletal & cardiac muscle; Not cardiac specific so (-) results r/o MI
Heparin induced thrombocytopenia
Immune-mediated disorder in which antibodies form against the heparin-platelet factor complex; Dx heparin as soon as HIT is suspected
Cardiac arrest
Occurs when the heart ceases to produce an effective pulse and circulate blood; Consciousness, pulse, and blood pressure are lost immediately
Acid-base balance
Measured in the concentration of Hydrogen ions in bodily fluids
Lung compensation takes…
5-15 mins *Sensitive to acid-base changes
Kidney compensation takes…
Up to 24 hrs *Much more powerful and result in changes in ECF composition
Arterial blood pH
7.35-7.45
PaCO2
35-45
HCO3
22-26
PaO2
80-100 on RA
Arterial blood gas
Provides information about the ventilation and diffusion of gases in the lungs and the acid-base balance of the blood; Evaluates CO2, pH, O2 saturation, and HCO3- levels
Partial compensation
If that value is < or > normal & pH is abnormal
Complete compensation
If that value is < or > normal & pH is normal
Respiratory acidosis
Caused by retention of carbon dioxide or conditions which impair gas exchange *Hypoventilation→Hypoxia
Metabolic acidosis
Happens when there is an excess of hydrogen or decrease of bicarbonate *Kussmaul respirations
Respiratory alkalosis
Caused by excessive loss of carbon dioxide *Hyperventilation
Metabolic alkalosis
Happens when there is an excess of bicarbonate or decrease of hydrogen
K levels in acidosis
Hyperkalemia
K levels in alkalosis
Hypokalemia
Oxygen transport
Transported from the lungs to the tissues; Most O2 combines with hemoglobin in RBCs and carried to tissues as oxyhemoglobin, and remaining is dissolved and transported in plasma and cells
Carbon dioxide transport
Must be transported from the tissues to the lungs and is continually produced in cell metabolism; Carried inside RBCs, combines with hemoglobin as carbhemoglobin, and transported in plasma as carbonic acid
Pneumonia
Inflammation of lung; Bacterial or viral lung infection
Early signs of hypoxemia
Dyspnea, restlessness, anxiety, fatigue, inc BP, and tachycardia
Late signs of hypoxemia
Cyanosis and coma
Nasal cannula
2-6 L; Humidify
Simple face mask
6-10 L; Prevents rebreathing exhaled CO2
Nonrebreather mask
10-15 L; Don’t forget to inflate
Venturi mask
2-15 L (Different colors); Helpful for pts at risk for hypercapnic resp failure
Aerosol mask
6-10 L; Helps ease bronchospasms and humidified
Face tent
10-15 L; Helpful for facial trauma/burns
High flow oxygen therapy
30-60 L; Oxygen delivered at a rate higher than traditional oxygen therapy to reduce work of breathing, improve gas exchange, and reduce anatomical dead space
CPAP
Provides a single set of pressure throughout sleep
BIPAP
Two distinct pressure settings for inhale and exhale
Atelectasis
Closure or collapse of alveoli; Absorptive, compressive, or obstructive
Rhinitis
Nasal and/or sinus mucosa inflammation/ irritation
Sinusitus
Inflamed sinuses *Often occurs after rhinitis
Obstructive sleep apnea
Airway collapses; Air flow blocked to lungs
Pharyngitis
Inflammation of pharyngeal walls
Tonsillitis
Inflammation and infection of the tonsils and lymphatic tissues located on each side of the throat
Laryngitis
Inflammation of the mucous membranes lining the larynx, possibly including edema of the vocal cords
Pulmonary tuberculosis
Highly communicable disease caused by Mycobacterium tuberculosis; Transmitted via aerosolization
Acute respiratory failure
A sudden, life threatening, inadequate ventilation and/or oxygenation
Precontemplation
Denial
Contemplation
Ambivalence
Determination/Preparation
Motivated
Action
Doing it
Maintenance
Living it
Relapse
Start over
Chantix
Prescription nicotine receptor blocker; Take 1 week before quitting, stay on for 12 weeks (GI s/e)
Pleural effusion
Excess fluid in pleural space *#1 sx is SOB
Chest tube assessment ABCDE
Air leak
Bubbling
Crepitus
Dependent loops
Excellent seal
Partial laryngectomy
Pt can still speak
Total laryngectomy
Patient will not have a voice and will have a stoma; May need radical neck dissection
Tracheostomy
Elective or emergency procedure for airway that can be temporary or permanent; Uncuffed for children < 8-years old
Stoma
Surgically created during surgery for total laryngectomy- required in order to remove all tissue that may be cancerous; Always permanent
Exercise stress test
Walking on treadmill to see if there is a change in VS, EKG, or ↑ pain
Dobutamine/adenosine
Medication given to ↑ HR, if the patient cannot walk on treadmill
Arteriosclerosis
Degeneration of arteries
Coronary artery disease
Buildup of plaque that causes arteries to narrow, leading to limited blood flow to the heart
Angina
Chest pain from temporary ischemia
Stable angina
Lasts 3-5 minutes; Treated with rest and NTG
Unstable angina
Lasts longer than 20 minutes; Does not go away
with rest or NTG *Medial Emergency!
Myocardial infarction
Complete blockage in the hearts arteries from lack of oxygen; Assess VS, EKG, labs, history, and start an IV
Percutaneous intervention
Balloon inflate with a stent to open artery; If cath-lab is not available, may give thrombolytics (Alteplase) but it has a high risk for bleeding!
Coronary artery bypass grafting
Bypasses the artery and places a graft (up to 4x)
Heparin therapy
Prevents formation of NEW clots; Start with bolus, then continuous infusion *Monitor pTT and platelets
QRS complex
0.06-0.12 sec
QT interval
<0.40 sec
Prolonged P wave
First degree AV block *Give beta blockers
Prolonged QRS
PVC
ST elevation
MI
ST depression
Ischemia
V tach
Shaped like a tombstone; QRS is wide— no P or T waves
A flutter
Shaped like a sawtooth; Affects the P-wave
SVT
Narrow QRS; Vagal treatment (bear down)
V fib
No QRS or P waves; Medical emergency *Defib the V-fib
Asystole
Give epi and CPR; Medical emergency!
Cardioversion
A synchronized shock used ONLY during the R wave of the QRS complex; Indicated for A fib, A flutter, SVT & V tach
Defibrillation
Asynchronous shock used during emergencies, often combined with CPR; Indicated for V fib & pulseless V tach