Paracetamol

Drug class:

analgesic and antipyretic: reduces pain and fever

Pharmacology

It blocks chemical signals that cause pain and raise body temperature

p-aminophenol derivative

A chemical compound that provides analgesic and antipyretic effects with minimal anti-inflammatory action.

Metabolism

liver and kidney

Indications

mild to moderate pain, fever

Contraindications

allergy, pt less than 1 yr

Hepatic dysfunction

Impaired liver function that may affect drug metabolism.

Side Effects

Nausea

Precautions

heptic dysfunction

Presentation tablet, liquid

500 mg paracetamol

24 mg/mL paracetamol

Schedule

S2 therapeutic poison

Onset / Duration / Half-life

10-60 minutes, 4 hours, 2 hours

route

PO per oral

Adult dose: Mild to moderate pain, fever

0.5-1 g PO every 4 hours

Max adult dose

4 g in 24 hours