eq athlete + resp poor performance

VO2 vs VO2 max

Vol of o2 absorption

Max rate of o2 consumption in exercise / max aerobic capacity

Diffusion vs perfusion

D- passive gas exchange

P- gas removal from lungs via blood

What can dec pul gas exchange

Inc pul resistance

Dec alv/pul compliance

Resp causes of poor performance

Dynamic airway collapse

Muscle disease

Dec CO

Dec Hb

Dec gas exchange

Exercise induced pul H - what lung does negative pressure inc in inspiration

Dor

Exercise induced pul H - Causes of capillary rupture (inc speed/work)

Inc CO

Inc BP

Inc negative pressure in dor lung in inspiration

Veno occlusive remodelling

Exercise induced pul H - Which lungs usually affected

Cd dor

Exercise induced pul H - Epistaxis bi or unilateral

Bilateral

Exercise induced pul H - Dx

CE

Endoscope <2hrs post race

BAL <14d post race

Exercise induced pul H - Tx

Rest

Supportive

NSAID

Blood transfusion

Exercise induced pul H - How does fibrosis occur

Macrophages, infl → alveolar architecture destruction → thickening, fibrosis

Exercise induced pul H - Management

Furosemide to remove fluid

Rest

Exertional myopathies - CS

Sweating, stiff, colic, dark urine (myoglobinuria), poor performance, inc CK + AST

Exertional myopathies - Sporadic causes

Dec Se + Vit E

Poor training

Inc sugar diet

Exertional myopathies - Recurrent exertional rhabdomyolysis common animals from Ca release

Thoroughbred

Young, stressed

Fillies

Exertional myopathies - polysaccharide storage myopathy pathogenesis

Amylase resistance polysaccharide storage in muscle → damage

Exertional myopathies - polysaccharide storage myopathy 1 vs 2

1- genetic test, drafts, ponies, sugary diet

2- muscle biopsy, warm bloods