cns pathology labs

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32 Terms

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g: purulent patches

m: focally dense inflammatory cellular infiltrate

tissue edema

acute pyogenic meningitis

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acute pyogenic meningitis

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acute pyogenic meningitis

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brain abscess

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swelling liquefied center filled with pus

brain abscess

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in children and cerebellum

g: circumscribed

cystic mass

solid mural nodules

m: bipolar astrocytes

grade 1: pilocytic astrocytoma

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g: ill defined

infiltrative

white growth

m: moderate cellularity

moderate atypia

fibrillary/ protoplasmic astrocytes

grade 2: low grade diffuse atrocytoma

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g: infiltrative growth

m: high cellularity

mitotic activity

no necrosis

pleomorphic astrocytes

grade 3: anaplastic astrocytoma

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g: infiltrative growth

large

hemorrhage

necrosis

cyst

m: high cellularity

marked cell anaplasia

palisading necrosis

vascular endothelial proliferation

grade 4: glioblastoma multiforme astrocytoma

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grade 1: pilocytic astrocytoma

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grade 1: pilocytic astrocytoma

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grade 2: low grade diffuse atrocytoma

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grade 2: low grade diffuse atrocytoma

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grade 3: anaplastic astrocytoma

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grade 3: anaplastic astrocytoma

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grade 4: glioblastoma multiforme astrocytoma

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grade 4: glioblastoma multiforme astrocytoma

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intra axial

slow growing

dystrophic calcification

closely packed cells

fried agg appearance

oligodendroglioma

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oligodendroglioma

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intra axial

in 4th ventricle

childhood and adolescence

leads to hydrocephalus

m: grade 2 and 3

perivascular pseudorosettes

ependymal rosette

ependymoma

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ependymoma

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ependymoma

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medulloblastoma

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cerebellum and children

grade 4

highly malignant rapidly growing

subtle round cell

moderate pleomorphism

high mitotic count

homer wright rosettes

medulloblastoma

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meningioma

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psamomma bodies in meningioma

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meningioma

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concentric cell whorls

proliferated meningothelilal cells

oval cells indistinct cell borders

pale cytoplasm regular round nuclei

psamomma bodies

dystrophic calcification

meningioma

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brain metastasis

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tubule formation

well circumscribed and demarcated

hyperchromatasia

variation in nuclear size and shape

mitosis

brain metastasis

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shwannoma

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shwann cells

antoni A: spindle shaped elongated nuclei parallel bundles nuclei has palisade pattern

antoni B: larger ovoid haphazardly areanged microcytic stroma and myxomatous.

shwannoma