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Carprofen
NSAID
Good- long acting, central and peripheral, inflammatory post-op pain, no reaction with anesthetics;
Bad- inadequate for surgical pain
Ugly- interferes with homeostasis (clotting, hypotensive renal perf, GI like melena, ulcers),
Acepromazine
Drug Info: phenothiazine/sedative/dopramine antagonist/alpha 1 adrenergic antagonist
Good:
reliable tranq, anesthetic sparing, inexpensive, long-acting, reduced afterload, not controlled
Bad: no analgesia, no reversal, vasodilation (decrease BP) at high dose, long-acting, splenic enlargement/RBC sequestration
Ugly: hypovolemia, shock, anemia, limited cardiac output due to afterload reduction
Hydromorphone
Opioid; synergism for sedation; analgesia; full mu agonist
Good: titratable analgesia, intermediate duration of action, sedation
Bad: vomiting, decreased resp, decreased HR, controlled
Ugly: deep corneal ulcer or esophageal FB due to vomiting
Morphine
Analgesia; full mu opioid; NOT VERY LIPOPHILIC and not readily absorbed systemically -> makes for best choice as epidural
Good: titratable analgesia, inexpensive, long-acting, sedation
Bad: vomiting, decreased respiration, decreased HR, histamine release, controlled
Ugly: vomiting detrimental; methadone an alternative
Propofol
GABA agonist; IV only
Good: rapid induction; short-acting
Bad: transient apnea, transient BP decrease, short shelf life, no analgesia
Ugly: repeated exposure in cats
Isoflurane
Inhalant anesthetic
Good: more potent (less to achieve same effect), cheaper
Bad: drop BP, hypoventilation, malignant hyperthermia
How do you calculate drug volumes for anesthesia?
Multiply mg dose x weight in kg
Divide value by drug concentration on bottle
How do you calculate the rate of IV fluid administration?
(weight in kg) x (5 ml/kg*hr) x (15 drops/ml if >10 kg weight with normal set OR 60 drops/ml is
Calculate the IV fluid rate in an 8 kg dog.
(8 kg) x (5 ml/kg*hr) x (60 drops/ml) x (1 hr/60 min) x (1 min/60 sec) = 0.67 drops/sec with microdrip set
Calculate the IV fluid rate in a 14 kg dog.
(14 kg) x (5 ml/kg*hr) x (15 drops/ml) x (1 hr/60 min) x (1 min/60 sec) = 0.29 drops/sec with normal set
What do you need to set up the induction station?
1. ET tubes
2. Inflation syringe
3. IV Cath supplies
4. Gauze tie
5. Dry gauze
6. Laryngoscope
What catheter supplies are needed? (4)
1. Catheter
2. Tape strips
3. T-port
4. Saline
What size catheter is appropriate for a cat, beagle, and coonhound?
Cat: 22g
Beagle: 20g
Coonhound: 18g
You should flush the ------, not the catheter.
T-port (needleless)
Know how to place an IVC and do IM and SQ injections.
K
What size laryngoscope is needed for a cat, Beagle, and Coonhound?
Cat: 0-1 Miller
Beagle: 2 Miller
Coonhound: 3 Miller
What is the induction agent?
Propofol
How do you assess induction dose if premeds cause slight, moderate, or profound anesthesia?
Slight: 1/3- all induction dose
Moderate: 1/2-2/3 induction dose
Profound: 1/3-1/2 induction dose
What should be started that must be temporarily stopped to bolus induction agent?
IV fluids
What is the role of the assistant while intubating?
1. Grasp outside maxilla
2. Allow jaw to drop open
3. Use gauze to exteriorize tongue
What THREE things should clue you to give additional induction agent?
1. Jaw tone
2. Movement
3. Coughing/swallowing
Describe how to intubate.
1. Laryngoscope in left hand
2. Place tip at base of tongue under epiglottis
3. Push down to expose glottis
4. ET tube in right hand, place between arytenoids
5. Advance to premeasured length
6. Hook up breathing circuit
How can you verify ET tube placement? (4)
1. Visualization between cords
2. Auscultate breath sounds
3. Chest expansion when given breath
4. Tube condensation
What are the roles of each person during epidural placement?
Surgeon keeps sternal
Assistant monitors
Anesthetist places
What must be done prior to placing epidural?
Place an esophageal stethoscope and monitor vitals and depth every 5 minutes
Position patient and clip/prep insertion site
What needle size is used for an epidural?
Same as IV catheter per type of animal
Name the FOUR major steps in placing an epidural.
1. Palpate L7-S1
2. Place finger on L7
3. Insert spinal needle below finger
4. Pop through ligament
What TWO signs tell you your epidural is in the correct location?
1. Hanging drop
2. Loss of resistance
What FIVE things do you do immediately after epidural?
1. Disconnect from breathing circuit
2. Position in dorsal
3. Reconnect to breathing circuit
4. Place doppler
5. Surgeon prep (shave/vacuum/initial prep)
What is the extubation criteria? (3)
1. Cough
2. Swallow
3. Lifting of head
True or False: The patient needs to only show one of the extubation criteria to be appropriately extubated.
True!
How do you set up and perform a functions check on an anesthesia machine?
Connect oxygen supply -> attach breathing circuit and reservoir bag -> close pop-off valve -> occlude patient end -> pressure to 20 cmH2O for 30 seconds to check for leak -> open pop-off valve -> THEN stop occluding with your thumb
Describe the advantages and disadvantages of either type of breathing circuit.
Circle Advantage: low FGF (4-30), preservation of heat and moisture, less environmental pollution, easier to ventilate
Circle Disadvantage: higher resistance, technologically complex, constrained to distance, equilibrate circuit to new concentration
NRB Advantage: low resistance, simple, no distance limitation, immediate control of inspired concentration
NRB Disadvantage: high FGF (150-300), loss of heat and moisture, environmental pollution, harder to control ventilation
When should you use a rebreathing circuit over a circle breathing circuit?
What is MAC and how does it apply to the individual patient?
Standard index of potency
Low MAC = more potent
High MAC = less potent (need more to get effect)
To calculate MAC, divide iso number by MAC 1.3
Iso: 1.3-1.6
Increased with hyperthermia and CNS stimulants
Decreased with pregnancy, hypothermia, extremes of age, other anesthetic agents (pre-med/injectables)
Multimodal management can help keep anesthetized even if MAC low because lower MAC = less inhalant needed and avoid inhalant side effects (cardiovascular depression, resp depression, better BP)
What should be your initial inhalant setting based on premed effect?
Slight/none: 2%
Moderate: 1.5%
Profound: 1.25%
What are the effects of improper inhalant concentrations?
Too light: everything increases
Too deep: everything decreases
How do you set an initial fresh gas flow rate?
Initial should be 2L/min; after 4 time constant on circle (prep and surgery): use 10-20 ml/kg/min
How can you apply the concept of time constant to determine rates of change in a circle breathing system?
The time constant helps predict how quickly a circle system changes its gas composition after changing FGF. It is calculated as time constant = circuit volume/FGF rate. After 1 time constant about 63% of old gas has been replaced. 4 time constants will be 98% and basically equilibrated.
Increasing FGF decreases the time constant and allows faster changes in anesthetic concentration, which decreasing flow increases the time required for equilbration.
FGF is the OXYGEN only.
How do you set an appropriate maintenance fresh gas flow rate?
10-20 ml/kg/min
What are the normal values for physiologic parameters? FINISH
HR/Pulse: 60-120 bpm
RR: 8-20 breaths/min
BP: SAP >90, MAP >60
ETCO2: 35-45 mmHg
Temp: 100-102.5 F
PCV: 35-55%
TP: 5.5-7.5
Glu: 70-120 mg/dL
What are the effect of abnormal physiologic parameters?
Heart rate: decreased (decreased perfusion, hypothermia); increased (hypovolemia, hypoxemia, hypercapnia)
BP: decreased (decreased perfusion, vasodilation); increased (pain, hypercapnia)
Low SPO2: hypoxemia
High ETCO2: hypoventilation/hypercapnia -> respiratory acidosis
Low ETCO2: hyperventilation; low cardiac output
RR: decreased (hypoventilation, hypercapnia)
Temp: decreased (decreased metabolism, delayed drug metabolism, arrhythmias); increased (increased metabolic demand; malignant hyperthermia)
How do you assess parameters of anesthetic depth?
Light: central eye position, strong palpebral, rigid jaw tone
Medium (ideal): ventromedial eye position, slight palpebral, slacking jaw tone
Deep: central eye position, no palpebral, loose jaw tone
What do you do if the patient is too deep?
- allow 15 minutes for equilibration
- decrease by 0.25%
-allow 15 minutes
- reassess
- repeat as needed until in adequate surgical plane
- do not go below 0.75%
What do you do if the patient is too light?
- turn vaporizer to maximum until back to ideal surgical plane
- increase oxygen flow rate to max until back
- increase 0.25% from previous
What do you do if there is surgical stimulation but no depth change?
What do you do if they get lighter due to it?
Give hydro
Adjust depth and give hydro
Describe anesthetic depth using planes and stages.
Stage I: voluntary movement and loss of consciousness
Stage II: stage of involuntary excitement
Stage III, Phase I: light (movement, strong to moderate jaw tone, central eye position, has palpebral, increased to normal HR, rr, response to surgical stimulation)
Stage III, Phase II: medium (the goal; ventromedial eye, no movement, moderate to absent jaw tone, normal HR, RR, response to stimulation)
Stage III, Phase III: deep
Stage IV: extreme (no corneal reflex, eyeballs central, respiratory arrest followed by CV collapse, decreased HR, RR, surgical stimulation)
How do you use a Doppler?
1. Find cuff 30-40% limb circumference
2. Place probe just distal to cuff and tape it there with jelly
3. Adjust until you hear a clear, strong pulse sound
4. Inflate until Doppler sound disappears then inflate 20-30 more
5. Deflate slowly, about 2-5 mmHg a second
6. The pressure at which you first hear the pulse return is your systolic arterial pressure (SAP). Should be above 90.
7. Take 3 readings and use the average.
What are the treatments for hypotension?
1. Assess depth, decrease inhalant
2. LRS bolus 10 mg/kg X2
3. Vetstarch bolus 5 mls/kg X2
4. Consult instructor if unreseolved
What are the signs of surgical stimulation?
Increased HR, Increased BP, Increased RR, Increased resp effort, somatic movement, swallowing, tense/rigid, eye movement, Increased ETCO2, dilated pupils, sweating, tearing
How do you assess a patient for pain in the post-op period?
Glasgow pain scale