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Exam 3
Describe tooth anatomy
Crown - for mastication and chewing
Neck - In gumline
Root - support and attach tooth to surrounding tissues
Gum - gingiva
Enamel

Symptoms of caries
No initial symptoms, but a progressive lesion on tooth
Sensitive to stimuli (heat, cold, sweetness, chewing)
Continuous pain + difficulty chewing if lesion invades dental pulp
Can progress to abscess and tooth loss
Caries etiology
Carbohydrates in diet
Oral bacteria
Host resistance alterations (orthodontic appliances, xerostomia, medications, radiation therapy, tobacco product use, alcohol use, immune system dysregulation)
Do not self-treat caries/when to refer
Symptoms of toothache, visualized lesion, entire tooth discoloration, bleed/swelling/reddened gums, persistent mouth odor despite use of fluoride toothpaste
Goals of therapy caries
Prevent or control dental plaque
Difference between plaque and calculus
Plaque - fresh/soft deposit removed by teeth brushing
Calculus - harder form of plaque removed by professional cleaning
Gingivitis symptoms
Inflamed gingiva, may progress to periodontal disease
Gingivitis etiology
Accumulation of supragingivial (above gingiva) bacterial plaque
Medications (calcium channel blockers, cyclosporine, phenytoin)
Reduced saliva flow (anticholinergics, antidepressants)
Tobacco
Pregnancy (hormones, connective tissue changes)
When to refer gingivitis
Swollen gums
Gums that bleed with brushing or flossing
Receding gums
Darker red gums
Goals of therapy gingivitis
Prevent calculus formation, remove and control supragingivial plaque
Dietary non-pharm options for caries and gingivitis
Avoid highly cariogenic (caries-causing) foods
15% or more sugar
Sticks to teeth
Can remain in mouth after being chewed
Drink adequate water
Non-pharm options for plaque removal
Chewing sugarless gum x 20 min after a meal
Brushing & flossing (adults & children older than 5 years, electric or non)
Dental floss: at least once daily (no difference w wax)
Irrigating devices-removes minimal amount of plaque; supplement to brushing & flossing
Non-pharm options for caries and gingivitis prevention
Activated charcoal (novelty)
Probiotics - possible benefit for gingivitis prevention
Vitamin D - adequate vit D during pregnancy can reduce caries in children
Xylitol (sugar alcohol in sugarless gums) - no stat benefit
OTC treatment options for chemical plaque management + follow up
Fluoride, dentifrices (toothpastes), mouthrinses
Follow up with professional dental cleanings every 6 months
Toothpaste use in adults
Size of pea, BID
Soft toothbrush, change every 3-4 months
Use fluoride-containing toothpaste
Hold at 45° angle
Floss daily
Toothpaste use in children
Start brushing when teeth erupt with fluoride toothpaste
Younger than 3 - size of rice grain; older - pea size
Supervise and have parental education
Don’t use too much fluoride (flescks/stripes/brown spots on teeth, enamel pits)
Pharmacologic methods of prevention of caries and gingivitis
Dentifrices and ingredients
Dentrifrices for prevention of caries and gingivitis
Act directly on oral bacteria or disrupt plaque components to aid in mechanical removal by removing plaque/stains, reducing mouth odors, enhancing physical appearance
Ingredients in dentrifices
Abrasive (removes particles and superficial stains)
Humectant (moistening agent)
Sweetener, flavor
Surfactant (foaming and particle removal)
Binder/thickener (holds all ingredients together)
Anticaries activity agent
Dentrifrice abrasive categories
Low abrasion: 10-25% silica abreasives
Mild abrasion: baking soda
High abrasion: 40-50% (dicalcium phosphate, calcium pyrophosphate, calcium carbonate, alumina trihydrate)
Fluoride anticaries agent
Sodium fluoride & sodium monofluorophosphate - remineralize, strengthen weakened enamel, reduce gingivitis and sensitivity
Stannous fluoride - above + adds protective layer over teeth to prevent plaque, slight staining if use continuously for 2-3 months, removed at professional cleaning
Significance of fluoride
Fluoride is necessary, otherwise oral hygiene fails to reduce cavity incidence
Whitening dentrifices ingredients
NOT tooth-bleaching products
Baking soda, titanium dioxide, aluminum oxide +citrate salt + papain, peroxides
Chemotherapeutic agents that can be combined with whitening dentrifrice
Fluoride, potassium nitrate, stanous flouride, metal salts, essential oils, hydrogen peroxide, sodium bicarbonate
Plaque control mouthrinses ingredients + MOA
Aromatic oils: antibacterial, local anesthesia
Anticrobials: bactericidal activity
Phenol: local anesthetic, antiseptic, bactericidal activity
Mouthrinse adverse effects + cautions
AE - occasional burning, irritation of oral mucosa; maycause sloughing of oral epithelium
C - mouth ulcers or irritation, keep away from children, alcohol content issues (poisoning, oral cancer)
Mouthrinse use
Use 1-2 tbsp, 1-2x daily
Most effective before brushing except if it contains fluoride
Don’t eat/drink 30 mins after
Supervise under 12 yrs
Plaque control with gum
Increased saliva flow and mechanical removal of debris
Chew after eating, sugarless gum only
Halitosis symptoms
Bad breath caused by volatile sulfur compounds
Systemic and oral causes of halitosis
Systemic
• Medications: TCAs, first-gen antihistamines, oxybutynin, meclizine, Parkinson’s meds
• Kidney/liver failure
• Cancer
• Ketosis
Oral
• Poor hygiene
• Xerostomia
• Foods/beverages
• Garlic or onions
• tobacco
To not self-treat halitosis
Medical conditions associated with halitosis, persistent halitosis despite good oral hygiene
Mechanical and chemical halitosis prevention
Mechanical
Tongue brushing
Chemical
Zinc salts (reduce receptor binding for VSCs)
Chlorine dioxide (breaks disulfide bonds, oxidizes VSC precursors)
Oral pain causes
Exposure of dentin, injury to mouth or lips or with RAS or herpes simplex labialis, nerve pain of face, facial herpes zoster, cluster headaches
Dentin/tooth hypersensitivity
Develops due to exposure dentin and dentin tubules opening to oral cavity and tooth pulp
Oral pain symptoms
Short and stabbing/sharp
Chemical/physical stimulus to dentin reaches open tubule, tubule fluid flow increased → nerve stimulation → pain
Pain from hot, cold, sweet, sour liquids; hot or cold air on teeth
Do not self-treat for oral pain
Toothache
Mouth soreness associated with dentures
Fever or swelling
Loose teeth
Bleeding gums
Broken teeth
Severe tooth pain started or worsened by hot, cold, or chewing
Trauma to the mouth
Goals of therapy for oral pain
Repair damaged tooth surface via appropriate toothpaste
Correct inappropriate toothbrushing technique
Non-pharm options for oral pain
Stop triggers (acidic foods, aggressive toothbrushing)
Avoid toothbrushing within 30-60 min of acidic foods/drinks
Correctly brushing teeth with fluoride toothpaste
OTC treatments for oral pain
Standard toothpaste withfluoride
Desensitizing toothpaste (potassium nitrate 5% + fluoride, arginine 8% + calcium carbonate)
Follow up for oral pain
Standard toothpaste with fluoride & soft bristled brush
Continue if resolution after 7 days
14 days of desensitization toothpaste
If resolved, switch to regular strength fluoride toothpaste
Otherwise, refer
Potassium nitrate 5% + fluoride MOA + indication
Depolarizes nerves in tubules & pulp to block perception of stimuli;
seals exposed dentin
For hypersensitivity
Potassium nitrate 5% + fluoride PD
Onset 2 weeks
Duration of use and beyond
Potassium nitrate 5% + fluoride SE + DI
No SE
DI with sodim or stannous fluoride: calcium in foods/supplements
Potassium nitrate 5% + fluoride avoid, pregnancy, lactation
Avoid high abrasion toothpastes, whitening toothpastes
No concern in pregnancy or lactation
Potassium nitrate 5% + fluoride dosing
Brush with 1 inch strip BID
Arginine 8% + calcium carbonate MOA and indication
Depolarizes nerves in tubules & pulp to block perception of stimuli
For tooth sensitivity
Arginine 8% + calcium carbonate PD
Onset is 2 weeks
Duration of use and beyond
Arginine 8% + calcium carbonate SE + DI + avoid
No SE or DI
Avoid using fluoride toothpaste at same time
Arginine 8% + calcium carbonate dosing
Brush with 1 inch strip BID for an entire 2 weeks
Recurrent aphthous stomatitis (RAS)
Canker sore or aphthous ulcer
RAS etiology
Unknown for most patients
Triggers: stress, local trauma, food allergy/gluten sensitivity, hormonal
changes, genetic predisposition
• Systemic diseases (e.g. SLE, allergies, IBD, nutritional deficiencies, HIV)
RAS signs and symptoms
Epithelial, circular ulcer on nonketatinized, movable mouth surfaces
• Last 5 to 14 days, 0.5 to 2 cm
Do not self-treat RAS
If underlying cause
• Lesions present 14 days or more
• Frequent recurrence
• Sx of systemic illness
• Self-care ineffective
Goals of therapy for RAS
Relieve pain & irritation
2. Heal lesions
3. Be able to eat/drink & do usual oral care
4. Prevent secondary infection
5. Prevent recurrence
Non pharm options for RAS
Correct any diagnosed nutritional deficiencies
• Avoid food allergy triggers
• Avoid spicy/acidic foods if active lesions
• Avoid textured foods that can irritate lesions
Apply ice to lesions x 10 minutes; max 20 minutes in an hour
DIY salt water rinses (table salt in tap water, swish then spit)
OTC treatment options for RAS
Topical
1. Oral debriding & wound
cleansing agents
2. topical oral anesthetics
3. topical oral protectants
4. oral rinses
• Systemic : analgesics
Follow up for RAS
7 days of treatment or 14
days since lesion/s first
appeared
• Side effects of topicals: see
medical provider
Oral debriding and wound cleansing agents
Carbamide peroxide 10% to 15% in
anhydrous glycerin
• Hydrogen peroxide 3% (DIY)
• Sodium perborate monohydrate
• Sodium bicarbonate (DIY)
•
Oral debriding and wound cleansing agents MOA + use
Release of molecular oxygen
Use up to 4x daily for 7 days
Oral debriding and wound cleansing agents SE + avoid
Mouth tissue irritation
• Short-term tooth hypersensitivity
• Black hairy tongue
Avoid toothpastes containing sodium lauryl sulfate
Dosage/administration of carbamide peroxide 10% to 15% in anhydrous glycerin
Drops of carbamide peroxide
or hydrogen peroxide applied
x 1 min
• Rinse: carbamide peroxide
drops on tongue, mix with
saliva, swish x 1 min
Dosage/administration of hydrogen peroxide 3% (DIY)
50:50 mix of hydrogen
peroxide 3% & water: swish x
1 min
Dosage/administration of sodium perborate monohydrate
Sodium perborate
monohydrate powder:
dissolve in 1 oz water & use
right away
Dosage/administration of sodium bicarbonate (DIY)
Thick paste, expectorate
Topical anesthetics for RAS
*Benzocaine 5% to 20%
• *Butacaine sulfate 0.05% to 0.1%
• *Dyclonine 0.05% to 0.1%
Topical oral protectants and rinses for RAS
Barrier protectants protect, decrease frition, and provide temporary relief
Coat ulcers with topical oral protectants (denture adhesive, dissolvable patch, dissolves after 8-12 hrs)
Rinses like Listerine or saline rinse (1-3 tsp salt in 4-8 oz warm tap water)
Minor oral mucosal injury/irritation etiology
Dental procedures
• Accidental injury: biting tongue/cheek, abrasion from sharp foods
DNST minor oral mucosal injury/irritation
Same as tooth hypersensitivity
Goals of therapy Minor oral mucosal injury/irritation
Control discomfort, aid healing, prevent secondary bacterial infection
Nonpharm therapy for Minor oral mucosal injury/irritation
Sodium bicarbonate
• Baking soda ½ to 1 tsp in 4 oz water; swish x 1 minute then expectorate; discard extra; fresh each time
• Saline rinse
• MOA: debride, clean wound, stimulate health
• Salt 1 to 3 tsp in 4 to 8 oz warm water
• Ice x 10 minutes (max 20 min in an hour)
Pharmacotherapy of Minor oral mucosal injury/irritation
Same as RAS:
1. Topical analgesics and anesthetics
2. Oral protectants
3. Oral debriding/wound cleansing
• Astringents: tissue contraction, stop secretions
When to refer for Minor oral mucosal injury/irritation
Sx persist after 7 days treatment or 10 days of initial injury
Sx gets worse during treatment
Sx of infection develop (fever, redness, swelling)
Causes of herpes simplex labialis (HSL)
HSV-1, HSV-2, CMV, Epstein-barr virus, infected for life
Symptoms of HSL
Prodrome - burning, itching tingling, numbness
Visual - small, red papules of fluid-filled vesicles, inflamed border, crust on top of mature lesion
Spontaneous healing over 10 days
When to refer HSL
lesions present more than 14 days
increased outbreak frequency
symptoms of infection (fever, swollen glands, rash)
no prior cold sore
goals of therapy HSL
relieve pain and irritation, prevent secondary infection, prevent spread of lesions
non-pharm options for HSL
keep lesions clean
handwashing
avoid sharing utensils, drinking vessels
moisturize involved skin (petroleum jelly w clean finger)
avoid triggers that slow healing (stress, local trauma, wind/sun, fatigue)
facial/lip sunscreen if sun is trigger
tea tree oil, lysine, lemon balm
OTC treatment options for HSL
topical skin protectants
external analgesics/anesthetics
docosanol 10%
follow up recommendations for HSL
14 days
docosanol 10% cream MOA
inhibits fusion of virus to cell membrane, prevents viral infection
docosanol 10% cream indication
reduce duration and severity of HSL symptoms
docosanol 10% cream PD
decreases time to heal by ~1 day
docosanol 10% cream SE
none
docosanol 10% cream DI
none
docosanol 10% cream avoid
placing aspirin tablet on lesions, hydrocortisone, astringents, zinc sulfate
docosanol 10% cream dosing
apply 5x/day starting in prodrome until lesion healed, max 10 days
xerostoma
dry mouth
xerostoma etiologies
health conditions: sjogrens, diabetes mellitus, depression , crohn’s disease
radiation therapy
medications: 1st gen antihistamines, decongestants, diuretics, TCAs, antipsychotics, sedatives
excessive alcohol consumption
tobacco use
excessive caffeine use
mouth-breathing
xerostoma symptoms
dry mouth (less than 1.5 L saliva in 24 hrs)
difficulty talking, swallowing
mouth sores
haliotosis
altered taste, loss of appetite
tooth hypersensitivity
overtime: caries
when to refer xerostoma
tooth erosion, decay
candidiasis (fungal infection), gingivitis
decreased denture-wearing time
mouth soreness due to dentures
fever or swelling
loose/broken teeth
severe tooth pain worsened by hot,cold, chewing
mouth trauma
sjogren syndrome
non-pharm options for xerostome
avoid triggers (tobacco, caffeine, alcohol, hot spice)
adjust or change causative meds if possible
limit sugary food/acidic food intake
chew gum with sugar alcohol (xylitol)
increase water consumption
cool mist humidifier in home
very soft bristled toothbrushes
OTC treatment for xerostoma
artificial saliva products (sprays, gels, gums, toothpastes)*
follow up recommendation for xerostoma
re-evaluate after 5-7 days of therapy
artificial saliva MOA
mimics natural saliva, replacement, not cure
artificial saliva indication
dry mouth
artificial saliva PD
onset minutes
duration few hours
artificial saliva se
hypersensitivity if preservatives
artificial saliva di
none
artificial saliva avoid
sodium-based products if low-salt diet, can decrease effectiveness
artificial saliva dosing
depends on product
gel: ½ inch of gel on tongue, spread throughout mouth
minimum frequency: after meals, at bedtime