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5 phases of outbreak investigation
describe the outbreak
collect and analyze data
implement control
follow-up
communication
do the 5 phases need to happen in order?
no, but all need to happen
outbreak definition
higher than expected number of cases
What is necessary to know to detect change and move forward?
number of cases
population at risk
agents causing disease
details of cases
singalment, timeline, signs, and symptoms
attack risk
cases/population at risk
morbidity
sick cases/population at risk
case fatality rate
dead cases/cases
case definition
set of criteria that individual must meet to be counted as ill in this outbreak
individuals we will do something with
must be specific enough to exclude cases not due to this outbreak
must be sensitive enough to include those with disease
must be practical to use
must include: who (individuals), what (pathogen, syndrome, test result), modifiers (other things that identify those at risk)
can you change your case definition?
yes
population at risk
individuals who could be or become cases in this outbreak based on current information
who you want to observe for cases and target for control measures
changes over course of an outbreak
before you have information, anyone is at risk
once you narrow down source, then fewer are at risk
sometimes when you know source, more are exposed than initially thought
all cases must be
members of population at risk
describe the outbreak includes
defining case and population at risk
epidemic curve

point source curve

propagated curve

sporadic curve

seasonal curve

patterns in epidemic curves
endemic or epidemic
endemic patterns
variation around a constant
seasonal
expected
epidemic patterns
point source
propagated
sporadic
unexpected
what is mean incubation period in point source curve
time from index case or common exposure to exposure peak