8.3 genome projects

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5 Terms

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define genome

complete set of genes in a cell

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define proteome

full range of proteins that a cell is able to produce

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how would you work out the proteome of a prokaryote from the genome?

  • Three bases code for one amino acid

  • So once you have sequenced the DNA you can work out the amino acid sequences and thus the primary structure of the proteins


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how could knowing the genome of a pathogen be useful?

  • You can work out the proteins the pathogen will express, including some of the surface antigens

  • You can then produce those antigens and use them to create vaccines against that particular pathogen


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why is it challenging to work out the proteome of a eukaryote, even if you know its genome?

1. There are introns within genes

2. There are regions of DNA which do not code for proteins but code for other things e.g. regulatory genes that code for siRNA or miRNA