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carbohydrates
include polysaccharides, which contain disaccharides, which are composed of two monosaccharides
lipids
include triglycerides, which are composed of fatty acids and glycerol
proteins
composed of peptides, which are made from amino acids
nucleic acids
include DNA and RNA, which are composed of nucleotides
high-energy compounds
include ATP, which is composed of nucleotides and phosphate groups
functional groups
atoms or clusters of atoms that are covalently bonded to carbon backbone
hydrocarbons
molecules consisting of only carbon and hydrogen
cell theory
the cell is the basic structural and functional unit for all life, all living organisms are comprised of at least one cell
polymer
a long molecule consisting of many similar building blocks (monomers)
dehydration synthesis
chemical reaction that joins two smaller molecules together to form a larger molecule while releasing a molecule of water as a byproduct
hydrolysis
a chemical reaction where a water molecule breaks one or more chemical bonds in a compound using water
monosaccharides
one carbon chain, quick energy, are the basic building block for all other carbohydrates
disaccharides
two carbon chains, for internal carbohydrate transport (in plants)
polysaccharides
more than two carbon chains, structural support and long term energy storage
peptide bonds
amino acids are held together by them, they are a type of covalent bond
polypeptide
an amino acid polymer; must fold up into complex conformations to be a protein
primary protein structure
connection of amino acids through covalent peptide bonds to make a chain
secondary protein structure
localized coils or folds formed by hydrogen bonds between the amino and carboxyl backbone groups
tertiary protein structure
determined by interactions amount various side chains (R groups) overall three dimension shape
quaternary protein structure
results when a protein consists of multiple polypeptide chains
prokaryotic cells
DNA is not in a nucleus, no membrane bounded organelles in the cytoplasm, have cell wall
eukaryotic cells
contain a nucleus and numerous organelles
plant cells
have a cellulose cell wall and can contain chloroplasts
cytoplasm
fluid and organelles within plasma membrane (all non-clear components inside plasma membrane)
nucleus
stores DNA
mitochondria
produce ATP, performs cellular respiration (metabolism/breakdown of glucose)
chloroplast
site of photosynthesis, has own DNA and ribosomes
ribosomes
read the mRNA instructions and synthesize proteins, made of ribosomal RNA and protein
endomembrane system
regulates protein traffic and performs metabolic functions in the cell
rough endoplasmic reticulum
functions: synthesis and export of secretory proteins and glycoproteins, protein folding
smooth endoplasmic reticulum
functions: synthesizes lipids, metabolizes carbohydrates, detoxifies drugs and poisons, stores calcium ions
the golgi apparatus
modifies products of the ER, sorts and packages materials into transport vesicles
cytoskeleton
tracks for vesicle transport, a dense network of fibers that supports and shapes the cell, anchors organelles, and is used in vesicle transport
lysosomes
organelles that break down molecules = recycling center
cytosol
fluid component of cytoplasm, viscous, water-based.
plasma membrane
separates cytoplasm from extracellular space (all cells have a plasma membrane)
amphipathic
they have both polar and non polar parts (phospholipids are amphipathic)
second law of thermodynamics
universal events naturally proceed towards disorder, meaning greater freedom
diffusion
random movement of molecules
solution
liquid with ions or molecules dissolved in it
solvent
the liquid in a solution
solute
the particles dissolved in the solvent
osmosis
diffusion of water through a membrane down its concentration gradient, towards high solute concentration
hypotonic solution
a liquid that has a lower concentration of dissolved solutes than the inside of a cell
hypertonic
a liquid that has a higher concentration of solutes than the inside of a cell
isotonic
a solution that has the same exact concentration of solutes and water as the cytoplasm inside a cell
channel proteins
let solute (bulk H2O or ions) cross membrane; solutes travel down concentration gradient via diffusion (passive - no energy input needed); solutes travel freely through without binding to transporter protein
Passive/facilitated transport proteins
allow small polar molecules to cross; solutes travel down concentration gradient via diffusion (passive - no energy input needed); carrier protein = solute must bind to transporter protein to cross
active transporter proteins
pump ions or polar molecules across; solute actively transported against concentration gradient (active - needs energy input); carrier protein = solute must bind to transporter protein to cross
voltage-gated ion channels
open in response to change in voltage
ligand-gated ion channels
binding of a specific small chemical (ligand) to the receptor
mechanically-gated ion channels
open in response to pressure
glucose transporter protein
passive transporter, must bind the solute, bidirectional
exocytosis
movement of material into the cell via the formation of a vesicle
endocytosis
movement of material from a vesicle out of the cell
dendrites (neuron)
collect electrical signals
cell body (neuron)
integrated incoming signals and generates outgoing signal to axon
axon (neuron)
passes electrical signals to dendrites of another cell or to an effector cell (another neuron or muscle cell)
facilitated diffusion
the spontaneous, passive movement of molecules or ions across a biological membrane from an area of high concentration to low concentration using specific integral transport proteins
Gibbs free energy
the energy available to do work or “useful” energy
energy coupling
the transfer of energy from one reaction to another in order to drive the second reaction
catabolic pathway
complex molecules are broken down to release energy
anabolic pathway
complex molecules are built from simpler molecules requiring energy
enzymes
physically bind the substrate, are found in all living things, accelerate reactions
activation energy
the minimum amount of energy required for a chemical reaction to occur
competitive inhibition
a process where an inhibitor molecule directly blocks a substrate from binding to an enzyme’s active site
noncompetitive inhibition
a type of enzyme regulation where an inhibitor binds to an enzyme at a location other than the active site with equal affinity for both the free enzyme and the enzyme-substrate complex
metabolism
total chemical reactions of an organism
oxidation-reduction (redox reactions)
the passage or electrons from one atom/molecule to another; reactions always take place together
glycolysis
first stage in cellular respiration, involves ten enzyme-catalyzed reactions
the citric acid (Krebs) cycle
carbons that entered cycle as Acetyl-CoA are oxidized to CO2
ETC blockers
inhibit flow of electrons and pumping of H+ by ETC; prevent formation of H+ gradient
uncouplers
allow pumping of H+, but disconnect it from ATP synthesis; let H+ sneak back into matrix without using ATP synthase
ATP synthase inhibitors
allow electron flow and creation of H+ gradient; directly inhibit activity of ATP synthase
rotenone
from the dried roots of the cube plant; disrupts electron transport in metabolism
oligomycin
antibiotic that blocks ATP synthase
respiration
oxidation of sugars to generate ATP
photosynthesis
reduction of CO2 and water to build sugar
autotrophs
produce complex organic molecules (e.g. glucose, starch) from simple inorganic molecules (e.g. CO2, H2O)
photoautotrophs
transform radiant energy (sunlight) into chemical energy (ATP) to produce complex organic molecules (e.g. glucose, starch) from simple inorganic molecules (e.g. CO2, H2O)
light
a form of energy; different wavelengths contain different amounts of energy; pigment molecules in chloroplasts absorb light energy
chlorophyll
the main pigment in plants; absorbs light energy;
the Calvin cycle
CO2 is reduced to produce sugar