Lecture 12 Trace Metals

Where are trace metals naturally found?

ENVIRONMENT so they are a high contaminant

What can trace metal CONTAMINATION cause?

Bad laboratory results

Which COLORED TOP is used for TRACE METALS?

Royal-Blue Color

Which ESSENTIAL metal is needed for hemoglobin synthesis and oxygen transport?

Iron

Which is the protein in blood that TRANSPORTS Fe3+ iron?

Transferrin

What percentage of transferrin is saturated with iron?

33%

What is the STORAGE FORM of iron?

Ferritin

Which protein EXPORTS IRON out of cells?

Ferroportin

Which enzyme REGULATES FERROPORTIN?

Hepcidin

At what point of the day is Iron the highest?

MORNING

Diurnal Variation

When collecting blood samples for Iron testing, what should be avoided?

AVOID Hemolysis

What is Total Serum Iron?

Amount of Iron in circulation in the blood

What is TIBC?

Total Iron Binding Capacity

HOW MANY TRANSFERRINS DONT HAVE IRON BOUND

What does it mean if someone has a HIGH TIBC?

Not enough iron in the blood

What does Ferritin tell you about the Iron in the body?

How much Iron is in storage

What is % Saturation?

How SATURATED the TRANSFERRINS are

Again low in low iron conditions

What is seen in Hemochromatosis?

BRONZE SKIN