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Pathogen
Lives off a host, harms the host
Infectious Disease
Caused by a pathogen
Noninfectious Disease
Caused by something other than a biological agent
Normal Flora
Microbes that live on you, there is access to the outside world, places the immune system cannot reach
Strain
One gene difference in a virus causing a difference in behavior
Do Prokaryotes have organelles?
No
Are prokaryotes multicellular or unicellular?
Unicellular
Do prokaryotes have a cell wall?
Yes, made of peptidoglycan
How many chromosomes do prokaryotes have?
one circular chromosome
What type of gene transfer do prokaryotes do?
Horizontal and vertical
What is horizontal gene transfer?
Can share genes with one another
What is vertical gene transfer?
pass down genes from parent to offspring
How do prokaryotes divide?
Binary fission
What is binary fission?
A form of asexual reproduction in which the parent divides into two new daughter bodies
Are their more prokaryotes or eukaryotes?
More prokaryotes
Do eukaryotes have organelles?
Yes
Are eukaryotes multicellular or unicellular?
The can be both
Do eukaryotes have a cell wall?
They may or may not have a cell wall
How many chromosomes do eukaryotes have?
Multiple
How do eukaryotes divide?
Mitosis or meiosis
Are bacteria prokaryotic or eukaryotic?
Prokaryotic
What are bacteria cell walls made out of?
peptidoglycan
Are bacteria motile or stationary?
Can be either
Are bacteria heterotrophic or autotrophic?
both
Are Archea Prokaryotic or Eukaryotic?
Prokaryotic
What conditions to archea typically like?
extreme conditions because they are usually extremophiles
Archea pathogens?
No known pathogens
Are protozoa eukaryotic or prokaryotic?
Eukaryotic
are protozoa multicellular or unicellular?
unicellular
What are protozoa cell walls made of?
no cell walls
Are protozoa stationary or motile?
both, but usually motile
Are protozoa heterotrophic or autotrophic?
heterotrophic
Protozoa pathogens?
malaria, brain eating amoeba, etc
Are fungi multicellular or unicellular?
Either one, they are dimorphic
What is dimorphic?
can change between unicellular and multicellular depending on the environment
Are fungi eukaryotic or prokaryotic
eukaryotic
Do fungi have cell walls
may or may not have cell walls made of chitin
Are fungi heterotrophic or autotrophic?
heterotrophic saprophytes
Saprophytes
eat dead organisms and waste products
Fungi pathogens?
yeast infection, athletes foot, etc
Is algae unicellular or multicellular?
both
Is algae prokaryotic or eukaryotic?
Eukaryotic
What are algae cell walls made of?
cellulose
Is algae heterotrophic or autotrophic?
autotrophic
Algae pathogens?
None
Can algae make you sick?
can indirectly make you sick ex. red tide poisoning
What are helminths?
worms
Are Helminths multicellular or unicellular?
multicellular
Do helminths have cell walls
no, they are animals
Helminth pathogens
tape worm, pinworm, etc
Why are viruses not considered lifeforms?
Acellular, no metabolism, DNA or RNA never both
What type of parasite is a virus?
obligate intracellular parasite
Obligate intracellular parasite
use host cells for their own replication
What viruses are pathogens?
all viruses are pathogens
Viruses are usually...
species and tissue specific
Microbial genetics
genetic study of microbes
Microbial Ecology
the study of the relationship between microorganisms and their environment
Microbial pathogenesis
study of microbe function
Immunology
study of the body's resistance to infectious disease
Epidemology
Study of how diseases spread
Emerging infectious disease
study of new diseases or known pathogens that have become more threatening
Scientific Method
observation, question, hypothesis, experiment, analysis
Spontaneous generation
Belief that simple lifeforms come from vital force
Biogenesis
simple lifeforms come from others like them
Golden age of microbiology
1800-1900s, big breakthroughs in microbiology
Louis Pasteur
Most influential microbiologist
Etiology
linking causative agents to disease
Koch's Postulates
linking certain microbes to certain diseases
Hook
first to use the microscope
Lavenhoek
Discovered microbes
Vaccination
Stops microbes from making you sick
Monomorphic bacteria
one shape, does not change
Pleomorphic bacteria
Change shape, no cell walls
Shapes of bacteria
Bacillis, coccus, spiral
What is the layer outside of the bacterial cell wall?
glycocalyx
What are bacterial appendages?
Things that stick outside of the cell wall
Example of bacterial appendages?
Flagella, fimbriae/pili, axial filiments
Flagella
motility
fimbriae and pili
attach to surfaces
Axial filaments
contract against one another for motility
Two main types of bacterial cell walls
gram positive and gram negative
Oddball bacterial cell walls
acid-fast cell walls
What is an L-form
have no cell walls but they will grow back
Which bacterial cell wall has a THICK layer of peptidoglycan?
Gram positive
Which bacterial cell wall has a THIN periplasmic space?
Gram positive
Which bacterial cell wall has teichoic and lipoteichoic acids?
Gram positive
protoplast
gram positive cell wall is removed but it grows back
Which bacterial cell wall has a THIN layer of peptidoglycan?
Gram negative
Which bacteria cell wall has an extra outer lipid membrane?
Gram negative
Which bacterial cell wall has a THICK periplasmic space?
Gram negative
Which bacterial cell wall has lipopolysaccharide?
Gram negative
what lipid causes endotoxin shock?
lipid a
Which bacterial cell wall has porins?
Gram negative
Spheroplast
a gram negative cell wall is removed but it grows back
cell membrane
has a lipid bilayer and amphipathic phospholipids
What is inside bacterial cytoplasm
Nuceloid, ribosomes, inclusions, cytoskeleton
Bacteria do not have a....
nucleus
ribosomes
read mRNA and make proteins
What is a bacterial inclusion?
Bacteria hoarding things inside it cell
Do bacteria have a prominent cytoskeleton?
No