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Vision
The sense that detects light (electromagnetic radiation, roughly 400 to 700 nm) and builds images of the world from it.
Retina
The light-sensitive neural tissue lining the back of the eye.
Rods
Photoreceptors specialized for dim light.
Cones
Photoreceptors for bright light, fine detail, and color.
Rhodopsin
The light-sensitive pigment in rods, made of opsin plus retinal.
Cone opsins (photopsins)
The pigments in cones, each tuned to a different range of wavelengths.
Dark current
The steady inward flow of positive ions (Na⁺ and Ca²⁺) through cGMP-gated channels in photoreceptors in darkness.
Transduction
Conversion of a physical stimulus (light, sound, chemicals, and so on) into an electrical signal in a sensory receptor cell.
Center-on / Center-off / Center-surround
Receptive-field organization of retinal ganglion cells and LGN cells.
LGN (lateral geniculate nucleus)
A thalamic relay that receives input from the retina and sends it to the primary visual cortex.
Primary visual cortex (V1)
The first cortical area to process vision, in the occipital lobe.
Retinotopic
Organized as a spatial map of the retina and visual field.
Feature selectivity
The property that different neurons respond only to specific features.
Simple cells
V1 neurons that respond to an oriented bar or edge at a specific position in the visual field.
Complex cells
V1 neurons that respond to an oriented bar or edge anywhere within their receptive field.
Dorsal stream
The 'where/how' pathway from the occipital lobe to the parietal lobe.
Ventral stream
The 'what' pathway from the occipital lobe to the temporal lobe.
SCN (suprachiasmatic nucleus)
A small area of the hypothalamus that acts as the body's master circadian clock.
Blind spot
The spot on the retina where the optic nerve exits (the optic disc).
Akinetopsia
Motion blindness, the inability to perceive movement.
Prosopagnosia
Face blindness, the inability to recognize faces despite otherwise normal vision.
Hemi-neglect
A neglect syndrome in which a person ignores one side of space or their own body.
Capgras delusion
The false belief that a familiar person has been replaced by an impostor.
Fregoli delusion
The false belief that different people are actually one person in disguise.
Visual snow
A condition in which people see persistent static or tiny flickering dots across their whole visual field.
Color blindness
Reduced ability to tell certain colors apart, usually from a missing or altered cone pigment.
Amplitude
The height of a sound wave, which corresponds to loudness.
Phase
The position within a wave's cycle at a given moment.
Tonotopic
Organized by sound frequency, so neighboring locations respond to neighboring frequencies.
Pinna
The visible outer part of the ear, which collects sound and funnels it into the ear canal.
Eardrum (tympanum)
The membrane that vibrates when sound arrives and separates the outer ear from the middle ear.
Ear bones (malleus, incus, stapes)
The three tiny middle ear bones that pass and amplify vibrations from the eardrum.
Oval window
The membrane at the entrance to the cochlea that transfers vibrations into the cochlear fluid.
Cochlea
The fluid-filled, snail-shaped structure of the inner ear that converts sound vibrations into neural signals.
Hair cells
The sensory receptor cells of the cochlea.
Tectorial membrane
A gelatinous membrane above the hair cells.
Depolarization and VOCs
When stereocilia bend, K⁺ enters and depolarizes the hair cell.
Odorants
Airborne chemical molecules that we detect as smells.
Olfactory epithelium
The tissue in the upper nasal cavity that contains the olfactory receptor neurons.
Olfactory receptor neurons (ORNs)
Sensory neurons whose cilia carry odorant receptors.
Olfactory bulb
The brain structure at the base of the forebrain that receives input from ORNs.
Glomerulus (glomeruli)
Spherical clusters in the olfactory bulb where ORN axons converge.
Mitral cells
The main output neurons of the olfactory bulb.
GPCRs (G-protein-coupled receptors)
Receptors that span the membrane seven times.
Taste buds
Clusters of taste receptor cells that detect chemicals such as sweet, sour, salty, bitter, and umami.
Anterolateral pathway
The ascending spinal pathway that carries pain and temperature information.
Nociception
The detection and neural processing of harmful or potentially harmful stimuli.
A fibers (Aδ)
Thin myelinated nerve fibers that conduct quickly and carry sharp, well-localized pain.
C fibers
Unmyelinated nerve fibers that conduct slowly and carry dull, burning, poorly localized pain.
First pain
The fast, sharp, well-localized pain felt right after an injury.
Second pain
The slower, dull, aching or burning pain that follows and lingers.
TRP channels (transient receptor potential)
Ion channels in sensory neurons that respond to temperature and chemicals.
Enkephalin
An endogenous opioid peptide that reduces pain transmission.
Sensitization
Increased responsiveness of pain pathways after injury or repeated stimulation.
Phantom pain
Pain felt in a limb or body part that has been amputated or lost.
Ascending tracts
Spinal cord pathways that carry sensory information up to the brain.
Descending tracts
Pathways that run from the brain down the spinal cord.