Fatty Acid Synthesis and Lipogenesis

Vocabulary flashcards covering key terms and definitions from the lecture notes on fatty acid synthesis and lipogenesis.

De novo fatty acid synthesis

The process of synthesizing fatty acids in the body, in addition to dietary intake.

Adipose tissue

The primary location for triacylglycerol synthesis.

Acetyl CoA Carboxylase

The enzyme that converts Acetyl CoA to Malonyl CoA.

Acyl Carrier Protein (ACP)

A protein to which Malonyl CoA and Acetyl CoA are bound during fatty acid synthesis.

Ketoacyl Synthase

Enzyme required in fatty acid synthesis

Ketoacyl Reductase

Enzyme required in fatty acid synthesis

Dehydratase

Enzyme required in fatty acid synthesis

Enoyl Acyl ACP Reductase

Enzyme required in fatty acid synthesis

Thioesterase

Enzyme required in fatty acid synthesis

Formation of Malonyl CoA

The committed step in fatty acid synthesis.

Pentose shunt and malic enzyme

The primary sources of NADPH for fatty acid synthesis.

Palmitoyl CoA

Inhibits fatty acid synthesis.

Insulin

Stimulates fatty acid synthesis.

Phosphatase

Pathways that remove a phosphate.

Synthesis of fatty acids

Is stimulated when diet is carbohydrate rich