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Neurons
Individual cells in nervous system that receive, integrate, and transmit information
Soma
Neuron cell body, contains cell nucleus and much of chemical machinery common to most cells
Axon
Long, thin fiber, transmitting signals away from soma to other neurons, muscles, or glands
Myelin Sheath
Sometimes on axons. Speeds up transmission of signals, prevents axons from sprouting in new directions.
Terminal Buttons
At the end of axons. Small knobs secreting neurotransmitters. Messengers activating neighboring neurons.
Synapses
Where neurons interconnect—information transferred between neurons
Glia
Cells found throughout the nervous system providing support for neurons. Generally much smaller than neurons and supply neurons with nourishment, remove their waste products, provide insulation, and have complex role in human embryo’s development.
Resting Potential
Neuron’s stable, negative charge when cell is inactive
Action Potential
A change in the ion distribution leads to a shift in the neuron’s electrical charge traveling along the axon
Absolute Refractory Period
Minimum length of time after an action potential during which more can’t begin
All or None Law
Either neuron fires or doesn’t—action potentials are the same size regardless of stimuli.
Presynaptic Neuron
Neuron that sends the signal across the synaptic cleft
Postsynaptic Neuron
Receives signal sent across the synaptic cleft
Synaptic Cleft
Microscopic gap between terminal button of one neuron and the cell membrane of the other neuron. Signals must cross the gap.
Neurotransmitters
Chemicals transmitting information between neurons, mostly stored in sacs in terminal buttons called synaptic vesicles.
Synaptic Vesicles
Sacs in terminal buttons storing neurotransmitters.
Postsynaptic Potential
Voltage change at receptor site on postsynaptic cell membrane. Don’t follow the all-or-none law.
Excitatory PSP
Positive voltage shift, increased likelihood the postsynaptic neuron will fire action potentials.
Inhibitory PSP
Negative voltage shift, decreased likelihood the postsynaptic neuron will fire action potentials.
Acetylcholine
Neurotransmitter—only one between motor neurons and voluntary neurons. Contributes to arousal, attention, and memory. Inadequate supply in certain areas of the brain is associated with the memory loss in Alzheimer’s
Monoamines
Category of neurotransmitters encompassing dopamine, norepinephrine, and serotonin. Regulate much of everyday behavior.
Dopamine
Neurotransmitter. Used by neurons controlling voluntary movements. “Feel-good” hormone. Low levels are linked to Parkinson’s, restless leg syndrome, ADHD, and depression, and schizophrenia is associated with both high and low levels.
Serotonin
One of many neurotransmitters contributing to the regulation of sleep and arousal, also a “feel-good” neurotransmitter that deals with feelings of calmness. Low levels associated with anxiety, depression, and OCD.
GABA
Amino acid producing inhibitory PSPs, responsible for much of central nervous system inhibition.
Endorphins
Internally produced chemicals resembling opioids in structure and effects. Widely distributed in the body. Contribute to modulation of pain.
Multiple Sclerosis
Disruption to the myelin sheath leading to a lack of communication between neurons.
Computerized Tomography (CT)
Computer-enhanced X-ray of brain structure, combining readings from many angles.
Magnetic Resonance Imaging (MRI)
Uses magnetic fields, radio waves, computerized enhancement to map out brain structure. 3D pictures with high resolution.
Lesioning
Destroying a piece of the brain to study what happens when it’s disabled. Largely limited to animal research.
Positron Emission Tomography (PET)
Radioactive markers to map chemical activity in the brain over time.
Functional MRI (fMRI)
Monitors blood flow and oxygen consumption in the brain. Maps brain activity with great precision.
Cerebellum
Relatively large, folded, adjacent to back surface of brainstem. Deals with coordination of movement, critical to sense of equilibrium + physical balance, sensing limb position.
Medulla
Attaches to spinal cord. Controls essentials and mostly unconscious functions.
Pons
Bridge of fibers connecting the brainstem with the cerebellum. Several cell bodies involved with sleep and arousal.
Reticular Formation
At the central core of the brainstem. Contributes to modulation of muscle reflexes, breathing, pain perception. Has a role in regulating sleep and wakefulness.
Thalamus
Relay station. All sensory information (except smell) must pass through this structure to get to the cerebral cortex. Composed of somas relaying sensory information to specific parts of the cortex. Seems to play active role in integrating information from various senses.
Hypothalamus
Regulates biological needs. Located near the base of the forebrain. Deals with fighting, feeding, fleeing, and mating.
Limbic System
Loosely connected network of structures on the border between the cerebral cortex and deeper subcortical areas that deals with emotions.
Hippocampus
Role in memory processes—creating new memories.
Amygdala
Structure with a role in learning fear responses and processing other emotional responses.
Cerebrum
Largest and most complex part of the brain. Includes areas responsible for learning, remembering, thinking, and consciousness.
Cerebral Cortex
Folded outer layer of the cerebrum.
Corpus Callosum
Thick band of fibers connecting brain hemispheres and enabling communication between the hemispheres.
Occipital Lobe
Most visual signals sent here, and visual processing begins here.
Parietal Lobe
Registers touch, involved in integrating visual input and monitoring the body’s position in space.
Temporal Lobe
Contains the primary auditory cortex for auditory processing. Damage to the area in the left hemisphere can cause difficulties in language/speech understanding.
Frontal Lobe
Contains the primary motor cortex, mirror neurons, and prefrontal cortex.
Mirror Neurons
Neurons firing/activated by seeing another performing the same action.
Primary Motor Cortex
Controls muscle movement. Amount of motor cortex dedicated to body part based on precision and diversity of movement.
Prefrontal Cortex
Affects decision making and self-control.
Neuroplasticity
The brain changes with time. Experience can sculpt features of brain structure.
Neurogenesis
Formation of new neurons.
Peripheral Nervous System
Nerves outside the brain and spinal cord. Includes nerves. Divided into somatic and autonomic nervous system.
Somatic Nervous System
Lets you feel the world and move around in it. Made of nerves connecting to voluntary skeletal muscles and sensory receptors.
Afferent Nerve Fibers
Axons carrying information to the central nervous system from the periphery of the body.
Efferent Nerve Fibers
Axons carrying information from the central nervous system to the periphery of the body.
Autonomic Nervous System
Made up of nerves connecting to the heart, blood vessels, smooth muscles, and glands. Controlled by the central nervous system. Controls automatic, involuntary, and visceral functions. Mediates much of physiological arousal occurring when people experience emotions. Divided into parasympathetic and sympathetic divisions.
Sympathetic Division
Mobilizes body’s resources for emergencies
Parasympathetic Divisions
Conserves the body’s resources.
Central Nervous System
Brain and spinal cord. Bathed in cerebrospinal fluid. Within skull and spinal column.
Cerebrospinal Fluid
Nourishes brain and provides protective cushion. Derived from carefully filtered blood. Substances in blood must cross blood-brain barrier to enter CSF.
Spinal Cord
Connects brain with the rest of the body through peripheral nervous system. Houses bundles of axons carrying the brain’s commands to peripheral nerves and vice versa.
Endocrine System
Second communication system consisting of glands secreting chemicals into the bloodstream to help control bodily functioning (hormones).
Hormones
Chemicals released by endocrine glands. Like neurotransmitters but slower and less specific. Tend to have intermittent releases.
Pituitary Gland
Releases variety of hormones fanning out within the body, stimulating actions in other endocrine glands.
Structural Neuroplasticity
Ability to physically change brain structure due to learning and experience.
Functional Neuroplasticity
Synaptic remodeling following brain disfunction or injury.
Dendrites
Dense branches of a neuron specialized to receive information.
Norepinephrine
Also known as noradrenaline. Part of sympathetic division. Increases alertness, arousal, and attention, and affects your sleep-wake cycle, mood, and memory. Low levels associated with depression, poor memory, lack of energy, and ADHD.
Electroencephalogram (EEG)
Test that measures electrical activity in the brain.
Epinephrine
Also known as adrenaline. Primary impact is as a hormone, but plays small role as a neurotransmitter. Helps you react quickly in cases of perceived danger (fight-or-flight response).