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Define surface area
The total area of an organism that is exposed to the external environment
Define volume
The total internal space/capacity of an organism
What is the coronation between surface area to volume ratio and the size of an organism?
As the size of an organism increases the surface area to volume ratio decreases and vice versa
Explain why the surface area of volume ratio decreases when the size of an organism increases
This is because volume increases more rapidly than surface area as size increases
Why is simple diffusion sufficient in single celled organisms?
They have a high service error of one more ratio so diffusion across the cell surface meets their needs
How does the large surface area and small volume benefit the organism?
The large surface area allows for maximum diffusion of nutrients and gases whilst the small volume means a diffusion distance to all parts of the cell is short
as organisms increased in size their surface area to volume ratio decreases what does this mean For the organism?
There is less surface area for diffusion compared to the size of the organism and the greater volume results in a longer diffusion distance to all parts of the organism
The surface area of volume ratio of an organism is related to its metabolic rate. true or false?
True
What is the metabolic rate?
It is the energy expended by that organism within a given period of time
Do small organisms with a high surface area to volume ratio, lose more or less heat to their surroundings?
They lose more heat to their surroundings meaning they need a relatively high metabolic rate to maintain body temperatures
Do large animals with a low surface area of volume ratio lose more or less heat to their surroundings?
They lose less heat meaning they can maintain body temperatures at a relatively low metabolic rates
Why does effective gas exchange need to take place?
In order to supply oxygen for respiration and to remove waste carbon dioxide
How do single cell organisms carry out gas exchange?
They carry our gas exchange at the cell surface by simple diffusion
Describe gas exchange in single cell organisms
The high surface area volume ratio means that diffusion occurs as a high rate over their relatively large surface area and diffusion distance from surface to all parts of the cell is short
How does gas exchange take place in insects?
Occurred via tracheal system
Describe gas exchange in insects
Air enters the bodies of insects via openings in the exoskeleton known as spiracles
Air flows into tracheae tubes and then into narrow tubes called tracheoles
Many tracheoles lead to the muscle fibres where their endings provide a large surface area to gas exchange
The movement of gases in the tracheal system mainly relies on diffusion gradient; Oxygen moves down its concentration gradient from the air into its respiring muscle cells and carbon dioxide move down its concentration gradient from the respiring muscle cells into the air
What may active insects need more of?
A more rapid supply of oxygen which they gain using rapid contractions of the abdominal muscles to Draw oxygen into the trachae Down a pressure gradient
What are fish adapted for?
To extract oxygen from water
What do you fish have to maximise the surf surface area for gas exchange?
They have gills
Where are gills located?
On each side of the head
What is each Gill arch attached to?
Two stacks of filaments
What is found on the surface of each filament?
Rows of lamellae
What is the surface of each lamellae made of?
A single layer of flattened cells
What do lamellae cover?
A vast network of capillaries
How is gas exchange in the gills maximised?
It is maximised by a countercurrent system
Why does the blood in the capillary system flow in the opposite direction to the flow of water as it passes over the gills?
To ensure that the concentration gradient is maintained along the whole length of the capillary
Does the water that enter the capillary have the highest or lowest oxygen concentration?
It has the highest oxygen concentration and this flows adjacent to the blood that is already partially oxygenated
Does the water that exit the capillary have the lowest or highest oxygen concentration?
It has the lowest and it is adjacent to the most deoxygenated blood
What do plants need oxygen for?
Respiration
What do plants need carbon dioxide for?
Photosynthesis
What are some adaptations of plant leaves that maximise the exchange of gases?
The spongy massive layer: airflows into and around the air spaces. The surfaces of the spongy mesophyll cells come into contact with the airspaces creating a large surface area for gas exchange
The stomata: These are paws on the underside of most leaves which allow air to enter and exit the leaf. God cells control the opening and closing of the stomata
The shape of the leaves: The leaves are flat and thin reducing diffusion distance for gases
How do you gases move through the cell?
They move in and out of the cells of the leaf by diffusion down their concentration gradient
What is the trade-off between adaptations for gas exchanging water loss?
Adaptations that increase the rate of gas exchange also tend to increase water loss. Therefore, organisms must balance maximising gas exchange with minimising water loss
Describe terrestrial insects
→ insects have a waterproof exoskeleton that prevents water loss by evaporation but the spiracles provide openings through which water vapour can be lost
→ insect features that minimise water loss include the ability to close spiracles and hair around the spiracles to reduce diffusion of water vapour
Describe xerophytic plants
→ Plants need to keep the stomata open to allow gas exchange to occur but opens the matter also allows the loss of water Vapour
→ Plants that live in conditions where freshwater is limited have evolved adaptations to conserve water including few stomata, stomata that are in pits, hairs that are around the stomata, Needle shaped leaves with a reduced surface area and a thickened waxy cuticle
What are some adaptations in cacti that reduce water loss?
Leaves reduced to spines to reduce surface area for water loss
The stem has a thick cuticle to prevent water loss
Where is Maram grass found?
Found on sand dunes
How are the leaves of Maram grass adapted for water loss?
Leaves can Roll up To reduce the exposure of surfaces to the wind
The rolling of the leaf provide deep grooves which protects the stomata
The exposed surface has no stomata And a thick cuticle
The inner surface of the leaf possesses a large number of hairs
What structures does the human gas exchange contain?
The alveoli, Bronchioles, Bronchi, Trachea and the lungs
What is the alveoli?
A series of tiny sacs With structural adaptations that maximise gas exchange. It is the site of gas exchange in the lungs
What are the bronchioles?
Narrow tubes that connect the alveoli to the bronchi
What is the bronchi?
A pair of tubes that connect the bronchioles in each lung to the trachea
What is the trachea?
The airway or windpipe that connects to bronchi with the mouth and nose
What are the lungs?
Two lungs in the chest cavity of the organs of gas exchange
What are all the organs in the gas exchange system?
The nasal cavity, Trachea, Pleural cavity, lung, External and internal intercostal muscles, bronchus, ribs, diaphragm, bronchiole and alveoli
What equipment should use when dissecting?
Scalpel, Dissecting scissors, Tweezers/forceps, Dissecting pins
What is a scalpel?
A sharp blade used for precise cutting
What are dissecting scissors?
Small, sharp scissors used for lower precision Tasks or separating layers of tissue
What are tweezers/forceps?
Useful for manipulating the specimen during dissection
What are dissecting pins?
May be useful for pinning sections of a specimen in place while working
What safety should be taken into consideration during dissection practical work?
→ a lab Coat, Gloves and eye protection should be worn to avoid contamination with biological material
→ Sharp clean blades should be used for eased and accuracy of cutting
→ Scalpel blades should cut away from the body
→ fingers should be kept away from the blade edges
Give a responsible use of biological material
Any biological specimen used for dissection should be from a reputable source and should be disposed of in the correct manner
When dissecting mammalian Lungs, what are key structures that could be seen?
Trachea supported by C shaped rings of cartilage; Scissors may be needed to cut through the tough cartilage of the trachea
Bronchi branching into each lung
Bronchioles
→ structure such as the alveoli can be harder distinguish in a dissecting lung though the spongy texture of lung tissue indicates that lungs contain many air filled sacs
on a fish where are the gills located?
Located on either side of the head beneath a bony flap known as the operculum
When dissecting bony fish gills What are the key structures which can be seen?
The Gill arch; This can be caught to remove the gill from the fish
The gill Filaments; Which have a feathery appearance
→ The lamellae Are too small to view by eye but can be examined under a microscope
How can you dissect an insect tracheal system?
Attach the insight to a dissecting board using pins
Cut the exoskeleton along the length of the abdomen
Add a saline solution to the abdomen to highlight the location of the trachea which will show as silvery tubes
→ trachea can me removed and viewed under a microscope
Describe the mammalian gas Exchange tissue
Alveoli that defer in size and shape
Alveolar walls that are one cell thick and made up of flattened cells
Nuclei that are shown as dark clots
Blood vessels in between the alveoli
Describe the fish gas exchange tissue
The gill arch Which provides a backbone for the gill filaments
Many filaments arranged along the Gill arch
Lamellae visible at higher power
Describe insect gas exchange tissue
→ electron microscopes can take clear images of insect gas exchange structures e.g. the spiracles
Describe the features of dicotyledonous leaves
Waxy cuticle
Epidermal layers
Palisade mesophyll layer
Spongy mesophyll layer
Stomata
Guard cells
How can the volume of air involved in gas exchange be measured?
Using a respirometer, an experimental set up that measures oxygen uptake in living organisms
What do respirometers Measure?
The measure changes and air pressure inside a container; as oxygen is consumed, the air pressure decreases causing a drop of coloured liquid to move towards the region of lower pressure
The distance moved by the coloured liquid in a given time can be used to calculate The volume of oxygen consumed
What do respirometers contain that aid their function?
Three way tap and manometer
What is a three-way tap used for?
Can be opened to allow air into the respirometer altering the internal pressure
This enables the return of the liquid bead to the starting point to allow easy repeat readings
What is a manometer and how is it used?
A narrow tube that contains liquid used to determine the difference in air pressure between 2 sealed containers
The liquid in the tube is drawn towards the container where the pressure is lowest and the distance moved by the fluid can be used to calculate the volume of gas removed
What is the alveolar epithelium?
Functions as a gas exchange surface; CO2 and O2 are exchanged between the alveoli and the capillaries in the process of diffusion
What are some adaptations of the alveolar epithilium that make it an effective gas exchange surface?
A large surface area, thin walls and a steep concentration gradient
How does the large surface area of the alveolar epithilium make it an effective gas exchange surface?
The lungs contain many alveoli increasing the surface area available for O2 and CO2 to diffuse
How do the thin walls make the alveolar epithelium an effective gas exchange surface?
The walls of the alveoli are one cell thick
Alveolar epithelium cells are flattened in shape
Gases have a very high diffusion distance
How does a steep concentration gradient make the alveolar epithelium an effective gas exchange surface?
The constant flow of blood through capillaries that are immediately adjacent to the alveolar epithelium means that oxygenated blood is carried away from the alveoli very quickly
This maintains the conc gradient necessary for diffusion of O2 to occur
How does gas exchange in the lungs occur?
O2 diffuses down its conc gradient from the air into the blood
CO2 diffuses down its conc gradient from the blood into the air
How are the conc gradients required for effective gas exchange maintained?
Ventilation in the lungs and the continuous flow of blood in the capillaries
What is ventilation?
The process of moving air in and out of the lungs and this involves breathing in/inhalation and breathing out/exhalation
Describe what happens when we breathe in
The diaphragm contracts and flattens and the external intercostal muscles contract
The ribcage moves upwards and outwards
Chest volume increases resulting in a pressure decrease in the thorax/ lungs/ thoracic cavity
Air moves into the lungs down a pressure gradient
Is the process of breathing in an active or passive process?
Active and therefore it requires energy for muscle contractions
describe what happens when we breathe out
The diaphragm relaxes and curves upwards and the external intercostal muscles relax
The rib cage moves downwards and inwards
Chest volume decreases resulting in a pressure increase
Air moves out of the lungs down a pressure gradient
Is breathing out an active or passive process?
Passive process that occurs due to the elastic recoil of the lung tissue
However during forced exhalation the process can become active:
Internal intercostal muscles contract to pull the ribs down and the abdominal muscles contract to push organs upwards against the diaphragm
These actions decrease the chest volume further increasing the pressure and for king more air out of the lungs
What is the pulmonary ventilation rate?
Volume of air an individual breathes per minute
What is tidal volume?
The volume of air inhaled or exhaled in one normal breath
What is breathing rate?
The number of breaths taken per minute
How do you calculate pulmonary ventilation rate?
PVR= tidal volume x breathing rate
What are the units for PVR, tidal volume and breathing rate?
PVR= cm3/min
Tidal volume= cm3 or mL
Breathing rate= breaths per minute
What is the effect of lung disease?
Reduces the lung function
What is lung cancer?
When tumours develop in the lungs due to uncontrolled cell division
The tumour may interfere with the normal working of the lungs e.g. by squeezing against blood vessels or blocking airways
What is COPD?
COPD causes damage to the lungs or airways reducing airflow and/or the rate of gas exchange
Range of conditions such as chronic bronchitis and emphysema
What do cigarettes contain?
Cancer causing chemicals
Chemicals that affect the ability to blood to transport
Chemicals that increase mucus production in the airways
What has air pollution been linked to?
Worsened COPD
asthma
Lung cancer
What is a risk factor?
Any factor that is linked to an increased probability of suffering from a particular condition or disease
What are the risk factors for lung disease?
Smoking
Air pollution
Exposure to certain chemicals at work
Genetics
Asthma
What considerations should be taken into account when analysing data from studies on risk factors?
Control variables- it is difficult to eliminate the effects of other variables e.g. diet, activity levels and genetics on the outcome of a study on a specific lifestyle factor
Sample size- the number of individuals in a study needs to be large enough to represent the population as a whole
Sample demographics- the sample needs to contain individuals who represent the target demographic
Correlation vs causation- risk factor data tends to rely on correlation and does not always indicate a casual relationship
Statistical tests: statistical testing should be used to determine whether any associations between variables are significant or due to chance
What is correlation?
An association between variables
What is a positive correlation?
As one variable increases so does the other
What is a negative correlation?
As one variable increases the other decreases
What are casual relationships?
Present when a change in one variable is caused by a change in the other
Is correlation equal to causation?
No; the 2 variables may be linked by a third factor that has not been taken into account by the research
What must researches do to demonstrate that a correlation indicates a casual relationship?
See the same results repeated across many studies
Demonstrate that the casual factor is occurring before the resulting change
Demonstrate the casual mechanism
Carry out control trials
What is the human digestive system?
An organ system that contains a series of organs that work together to digest and absorb food
What is the function of the mouth an salivary glands?
Food is ingested and teeth break it down into smaller pieces. Saliva is secreted into the mouth. The enzyme begins to digest starch into maltose
What is the function of the stomach?
Protease enzymes begin protein digestion
HCl provides a suitable pH for enzymes and destroys any pathogens in food
What is the function of the liver?
Bile salts are produced here
Bile salts aid the digestion of lipids as well as neutralising stomach acid as it exits the stomach