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HAV and HEV are transmitted through the __________ route, often due to contaminated food or water.
fecal-oral
HBV, HCV, and HDV are transmitted through __________ routes, which means exposure to infected blood.
parenteral
Acute liver infection symptoms may include general flu-like symptoms and mild to moderate pain in the __________ abdomen.
upper right
Chronic HBV infection can lead to chronic infection in __________ of cases, especially in infants.
90%
HCV frequently progresses to chronic liver disease, with __________ of infected individuals developing chronic infection.
85%
The RNA virus __________ requires the presence of HBV for replication.
HDV
A formalin-inactivated HAV vaccine is available for __________.
prevention
Treatment for chronic HBV infection includes antivirals such as alpha interferon and __________.
reverse transcriptase inhibitors
The 'core window' refers to a period during acute HBV infection when HBsAg may become __________.
undetectable
HCV is primarily screened using the __________ assay.
ELISA
Superinfection occurs when an individual with a chronic hepatitis infection, such as chronic HBV, becomes infected with a __________ hepatitis virus.
second
Total anti-HAV antibodies appear after IgM anti-HAV and indicate __________ to HAV.
immunity
HAV-IgM specifically detects IgM antibodies, indicating an acute __________.
infection
Markers such as HBsAg and anti-HCV are used to detect HBV and HCV infections in __________ donations.
blood
Elevated ALT levels suggest __________ cell damage.
liver
The initial laboratory findings in liver disease often include elevated levels of bilirubin, ALT, and __________.
AST