RAAS Active Agents

brand name for Benazepril?

Lotensin

generic name for Lotensin?

Benazepril

therapeutic class for Benazepril?

Antihypertensive

pharmacologic class for Benazepril?

ACE inhibitor

MOA for Benazepril?

Blocks conversion of angiotensin 1 to angiotensin 2

major characteristic of Benazepril?

dry cough (bradykinin), hyperkalemia, CONTRADICTION - Angioedema (bradykinin)

brand name for Enalapril?

Vasotec

generic name for Vasotec?

Enalapril

therapeutic class for Enalapril?

Antihypertensive

pharmacologic class for Enalapril?

ACE inhibitor

MOA for Enalapril?

Blocks conversion of angiotensin 1 to angiotensin 2

major characteristic of Enalapril?

dry cough (bradykinin), hyperkalemia, CONTRADICTION - Angioedema (bradykinin)

brand name for Fosinopril?

Monopril

generic name for Monopril?

Fosinopril

therapeutic class for Fosinopril?

Antihypertensive

pharmacologic class for Fosinopril?

ACE inhibitor

MOA for Fosinopril?

Blocks conversion of angiotensin 1 to angiotensin 2

major characteristic of Fosinopril?

dry cough (bradykinin), hyperkalemia, CONTRADICTION - Angioedema (bradykinin)

brand name for Lisinopril?

Prinivil; Zestril

generic name for Prinivil; Zestril?

Lisinopril

therapeutic class for Lisinopril?

Antihypertensive

pharmacologic class for Lisinopril?

ACE inhibitor

MOA for Lisinopril?

Blocks conversion of angiotensin 1 to angiotensin 2

major characteristic of Lisinopril?

dry cough (bradykinin), hyperkalemia, CONTRADICTION - Angioedema (bradykinin)

brand name for Quinapril?

Accupril

generic name for Accupril?

Quinapril

therapeutic class for Quinapril?

Antihypertensive

pharmacologic class for Quinapril?

ACE inhibitor

MOA for Quinapril?

Blocks conversion of angiotensin 1 to angiotensin 2

major characteristic of Quinapril?

dry cough (bradykinin), hyperkalemia, CONTRADICTION - Angioedema (bradykinin)

brand name for Ramipril?

Altace

generic name for Altace?

Ramipril

therapeutic class for Ramipril?

Antihypertensive

pharmacologic class for Ramipril?

ACE inhibitor

MOA for Ramipril?

Blocks conversion of angiotensin 1 to angiotensin 2

major characteristic of Ramipril?

dry cough (bradykinin), hyperkalemia, CONTRADICTION - Angioedema (bradykinin)

what does ACE stand for?

Angiotensin Converting Enzyme

pharmacologic class for all “-pril” endings?

ACE inhibitor

MOA for all ACE inhibitors?

blocks the conversion of angiotensin 1 to angiotensin 2

brand name for Candesartan?

Atacand

generic name for Atacand?

Candesartan

therapeutic class for Candesartan?

Antihypertensive

pharmacologic class for Candesartan?

ARB

MOA for Candesartan?

Blocks the receptor where angiotensin 2 binds

major characteristic of Candesartan?

Hyperkalemia

brand name for Irbesartan?

Avapro

generic name for Avapro?

Irbesartan

therapeutic class for Irbesartan?

Antihypertensive

pharmacologic class for Irbesartan?

ARB

MOA for Irbesartan?

Blocks the receptor where angiotensin 2 binds

major characteristic of Irbesartan?

Hyperkalemia

brand name for Losartan?

Cozaar

generic name for Cozaar?

Losartan

therapeutic class for Losartan?

Antihypertensive

pharmacologic class for Losartan?

ARB

MOA for Losartan?

Blocks the receptor where angiotensin 2 binds

MOA of Losartan?

Hyperkalemia

brand name for Olmesartan?

Benicar

generic name for Benicar?

Olmesartan

therapeutic class for Olmesartan?

Antihypertensive

pharmacologic class for Olmesartan?

ARB

MOA for Olmesartan?

Blocks the receptor where angiotensin 2 binds

major characteristic of Olmesartan?

Hyperkalemia

brand name for Telmisartan?

Micardis

generic name for Micardis?

Telmisartan

therapeutic class for Telmisartan?

Antihypertensive

pharmacologic class for Telmisartan?

ARB

MOA for Telmisartan?

Blocks the receptor where angiotensin 2 binds

major characteristic of Telmisartan?

Hyperkalemia

brand name for Valsartan?

Diovan

generic name for Diovan?

Valsartan

therapeutic class for Valsartan?

Antihypertensive

pharmacologic class for Valsartan?

ARB

MOA for Valsartan?

Blocks the receptor where angiotensin 2 binds

major characteristic of Valsartan?

Hyperkalemia

what does ARB stand for?

Angiotensin II Receptor Blocker

pharmacologic class for all “-sartan” endings?

ARB

MOA for all ARB?

blocks the receptor where angiotensin 2 binds

brand name for Sacubitril/Valsartan?

Entresto

brand name for Entresto?

Sacubitril/Valsartan

therapeutic class for Sacubitril/Valsartan?

heart failure

pharmacologic class for Sacubitril/Valsartan?

ARB + neprilysin inhibitor (ARNI)

MOA for Sacubitril/Valsartan?

ARB + neprilysin inhibitor which blocks action of neprilysin enzyme

major characteristic for Sacubitril/Valsartan?

Hyperkalemia

brand name for Spironolactone?

Aldactone

generic name for Aldactone?

Spironolactone

therapeutic class for Spironolactone?

Antihypertensive

pharmacologic class for Spironolactone?

Mineralocorticoid (Aldosterone) Receptor Antagonist (MRA)

MOA for Spironolactone?

Blocks receptors where aldosterone binds

major characteristic of Spironolactone?

Hyperkalemia, Hypotension

major characteristic of all drugs?

hyperkalemia