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excitatory neurotransmitters
chemical messengers that bind to postsynaptic receptors and increase the likelihood a neuron will generate an electrical signal
inhibitory neurotransmitters
chemical messengers that decrease the likelihood a postsynaptic neuron will fire
acetylcholine (ACh)
neurotransmitter that triggers contractions, regulates autonomic body functions, and supports brain cognition
norepinephrine
fight or flight, alertness, increase BP
glutamate
energy, learning and memory
dopamine
neurotransmitter and hormone that acts as a chemical messenger and plays a role in body’s reward system
serotonin
neurotransmitter and hormone that helps regulate mood, digestion, sleep-wake cycles, and appetite
GABA
main inhibitory neurotransmitter in the CNS; reduce stress, anxiety, mood, and sleep
substance P
relays pain signals and wound healing
endorphins
pain relief, mood regulation
multiple sclerosis (M.S.)
autoimmune disease that affects the CNS, damage to myelin and nerve fibers
myasthenia gravis
autoimmune disorder that interferes with communication between nerves and muscles, causing muscle weakness
depressants
slow down activity in CNS
alchohol
depressant that slows neural activity, reduces inhibitions, and impairs judgement, coordination, and memory
stimulants
increase activity in the CNS, often increasing alertness and energy
caffeine
stimulant that promotes wakefulness and reduces feeling of tiredness
cocaine
powerful stimulant that increases dopamine activity and can produce intense euphoria and energy
hallucinogens
alter perception, thoughts, and sensory experiences
marijuana
drug that can alter perception, memory, mood, and coordination
opiods
drugs that bind to opiod receptors to relieve pain and can produce euphoria
heroin
highly addictive opiod that produces intense euphoria and carries a high risk of overdose
tolerance
when repeated drug use causes the same dose to have less effect, leading a person
addiction
conditon involving compulsive substance use despite harmful consequences
physical dependence
when the body adapts to a drug and experiences withdrawal symptoms when it is reduced or stopped
psychological dependence
emotional or mental reliance on a substance to feel pleasure, cope, or function
withdrawal
physical or psychological syptoms that occur when a dependent person reduces or stops using a substance
hindbrain
lower region of the brain responsible for essential survival functions, coordination, and balance
brainstem
connects the brain to the spinal cord and controls essential functions such as breathing and heart rate
medulla
controls automatic functions such as breathing, heart rate, and blood pressure
pons
helps regulate sleep and arousal and assists with breathing and communication between brain regions
cerebellum
coordinates balance, posture, precise movements, and motor learning
reticular activating system
network involved in alertness, attention, and wakefulness
reward center
group of interconnected brainregions involved in motivation, reinforcement, and pleasure
hippocampus
helps form new explicit memories and supports spatial navigation
ventral tegmental area
brain region containing dopamine-producing neurons involved in reward and motivation
nucleus accumbens
region involved in reward, motivation, reinforcement, and addiction
prefrontal cortex
front part of the frontal lobe involved in planning, decision-making, impulse control, and working memory
cerebral cortex
brain's outer layer, responsible for complex processes such as thinking, perception, language, and voluntary movement
limbic system
group of interconnected brain structures involved in emotion, memory, motivation, and behavior
thalamus
relays most sensory information to the cerebral cortex, except smell
hypothalamus
regulates hunger, thirst, body temp, hormones, and other homeostastic functions
pituitary gland
releases hormones that regulate growth, reproduction, and other endocrine functions
amygdala
helps process emotions, particularly fear, threat, and emotional sugnificance
corpus callosum
thick bundle of nerve fibers connecting the brain’s left and right hemispheres
lobes
major divisions of the cerebral cortex, each associated with different functions
frontal lobes
involved in planning, decision-making, personality, impulse control, and voluntary movement
motor cortex
controls voluntary muscle movements
parietal lobes
process sensory information and help with spatial awareness
association areas
regions that integrate information from different brain areas to suppoty complex thinking, memory, and interpretation
somatosensory cortex
processes touch, pressure, pain, temp, and body-position information
occipital lobes
primarily responsible for processing visual information
temporal lobes
involved in hearing, language comprehension, memory, and aspects of emotion
contralaterality
principle that each brain hemisphere generally contols movement and receives much sensory information from the opposite side of the body
brain lateralization
specialization of certain functions in one hemisphere more than the other
split-brain procedure
surgery that cuts the corpus callosum to reduce the spread of severe epileptic seizures between hemispheres
hemispherectomy
surgery that removes or disconnects a large portion of one cerebral hemisphere, usually to treat severe neurological disorders
broca’s area
region, usually in the left frontal lobe, important for producing speech
wernicke’s area
region traditionally associated with understanding language
aphasia
language disorder caused by brain damage that can affect speaking, understanding, reading, or writing
brain plasticity
the brain’s ability to change its structure or function in response to experience, learning, or injury
neuroplasticity
another term for brain plasticity
CAT or CT scan
uses x-rays taken from different angles to create cross-sectional images of the brain; useful for detecting bleeding and skull injuries
MRI scan
uses magnetic fields and radio waves to create detailed images of brain structures without using x-ray
PET scan
uses a radioactive tracer to measure processes such as glucose metablosim and blood flow, helping researchers assess brain activity
fMRI
measures changes in blood oxygenation associated with neural activity to estimate which brain areas are active
EEG
records electrical activity produced by the brain using electrodes placed on the scalp
lesioning
damaging or removing a specific area of tissue to study its function or to treat a medical condition