AD Lecture 24

What are the three reasons why parvo was spread so quickly when it first emerged?

-shed in feces in enormous amounts

-very resistant to the environment

-no dogs had previous immunity

CPV 2 is ____% genetically similar to Feline Panleukopenia Virus

98%

What strain of parvo has the ability to infect cats?

CPV 2c

What is the current most common strain of parvo?

CPV 2b

Can parvo withstand freezing temps?

YES! - freezing temps protect/preserve the virus

How long will dogs shed parvo post infection?

Shed for 1 month post infection

Why are puppies the primary type of dogs being infected?

-unvaccinated <12 week

-Unvaccinated mom

-No colostrum - lack sufficient Ab protection

How is parvo transmitted?

fecal-oral route (fomites!)

what is the incubation period of parvo?

3 to 7 days between initial infection and onset of first clinical signs

Where does the virus enter the puppy's body?

Through the mouth

Where does it travel to and replicate in?

Travels to lymph nodes and replicates there

What will we see in the blood work of a puppy with parvo?

-Decreased WBC

-Decreased electrolytes (Na and K)

-Decreased glucose

-Increased PCV

Why do dogs get bloody malodorous diarrhea with parvo?

Because the virus can travel to the crypt cells of the intestines and cause necrosis and destruction of crypts, leading to diarrhea

What else can happen due to parvo destroying the crypt cells?

Bacteria can invade the blood stream causing septicemia

What is the main thing that causes death in parvo cases?

Severe dehydration from V/D or septicemia from loss of intestinal lining

Main ways to diagnose parvo

-Complete blood count (low WBC count = parvo)

-Fecal Parvo Idexx Snap test - tests for viral antigen in feces

What test is considered a confirmatory test for parvo?

PCR - detects iral DNA

What are the five main ways to treat parvo?

-Fluids

-Antibiotics

-Antiemetics

-Antiinflammatory agents

-Anti-ulcer

Best prevention method for parvo

Vaccinate!!

When should puppies be vaccinated for parvo?

weeks 8,12, 16

what is recommended for breeds such as rotties/dobies who are more predisposed to parvo?

Recommended fourth vx at 20 weeks