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If Babesia cannot be observed by microscopic examination of peripheral blood smear from a patient who is ill but has no travel history to a malaria endemic area, an acute infection with Babesia can be diagnosed by:
Test an acute and convalescent sera for a rise in IgG titer
Molecular technique to detect the organism
In suspected human monocytic ehrlichiosis (HME), if a patient has a supporting history and clinical symptoms, the diagnosis can be confirmed by a serological titer greater than
1:128
In cases of toxoplasmosis, diagnosis can be established by
PCR
IFA
Isolation of the organism
In cases of current toxoplasmosis infection the earliest that Toxoplasma abs can be detected is ____ after infection
Within the first 2 weeks
Heterophile antibodies can be characterized as
Reacts with horse and sheep RBCs
Absorbed by beef RBCs
Not absorbed by guinea pig kidney cells
The antigen expressed by Epstein-Barr (EBV) infected lymphocytes encoded by the virus include
Early antigen (EA)
Viral Capsid Antigen (VCA)
Epstein-Barr Nuclear Antigen (EBNA)
Common vectors of Lyme disease include all the following except
Dermacentor variabilis
Erythema chronicum migrans (ECM)
Harbors Borrelia burgdorferi in the advancing edge
Lyme disease is a _____ type of infection
Bacterial
Lyme disease is caused by a
Spirochete
Babesia is characterized by
Fever
Fatigue
Hemolytic anemia
In the eastern US, babesiosis is caused by
Babesia microti
Zika is transmitted primarily by
Mosquitos
West Nile Virus causes
Enchepahlitis
One of the most physical findings in adults with ehrlichiosis is
Fever
Toxoplasmosis is a _______ infection
Parasitic
The definitive host of Toxoplasma gondii is
Domestic cat
Toxoplasmosis is a serious health threat to
Patients with AIDs
Congenital toxoplasmosis can cause
Central nervous systems malformation
The method of choice for detecting IgM antibodies to toxoplasmosis is
Enzyme-linked immunosorbent assay (ELISA)
All of the following describe CMV except
Epidemic worldwide
(Describing it: Herpes family virus, DNA virus, Cell associated virus)
Transfusion acquired CMV infection can cause
Mononucleosis-like syndrome
Hepatitis
Rejection of transplanted organisms
EBV cause all of the following except
Neoplasm of the bone marrow
Can cause: Infectious mononucleosis, Burkitt lymphoma, Nasopharyngeal carcinoma
Anti-EBNA IgG does not appear until the patient has entered the
Convalescent period
What percentage of the worlds population is exposed to EBV?
95%
The use of horse erythrocytes in rapid slide tests for infectious mononucleosis increases their
Both sensitivity and specificity
EBV-Infected B lymphocytes express all of the following new antigens except
Cytoplasmic antigen
Does express: Viral Capsid Antigen (VCA), Early Antigen (EA), Nuclear antigen (EBNA)
With Rubella infection the appearance of ____ antibodies is associated with the clinical signs and symptoms, when present
Both IgG and IgM
The greatest risk of manifestation of anomalies in maternal rubella is _______ of gestation
First trimester
Acute Rubella infection lasts from ______ days
3 to 5
Rubella IgM antibodies reach peak levels at _____ days
7 to 10
Which of the following is a symptom of Streptococcus pyogenes infection?
Erythema Chronicum Migrants (ECM)
The classic tests to demonstrate the presence of streptococcus infections are
ASO and anti-DNase
Virulent serotypes of S. pyogenes produce proteolytic enzymes that cause _______ in a wound or lesion on extremity
Necrotizing fasciitis
Substances produced by S. pyogenes include all the following except
Interferon
Serological testing for S. pyogenes should compare acute and convalescent specimens collected _____ apart
Two weeks
Erythrogenic toxin produced by group A Streptococcus
Responsible for characteristic scarlet fever
Which is true regarding Streptolysin O found in Streptococcus species infections
Binds to sterols in the RBC membrane causing rearrangement of fatty acids
An elevated anti-streptolysin O (ASO) titer indicates
Recent streptococcal infection
FTA-ABS is a treponemal method
True
Rapid reagin plasma is a non-treponemal method
True
Direct examination of Treponema spirochete is most often performed by
Darkfield microscopy
The first diagnostic blood test for Syphilis is
RPR
Which of the following is a term for non-treponemal antibodies produced by an infected patient against components of their own or other mammalian cells?
Reagin antibodies
A false positive RPR can be caused by
Rheumatoid arthritis
Before clinical or serological manifestations, the incubation period for syphilis usually lasts
About 3 weeks
Tertiary syphilis is best evaulated by using
CSF
The presence of gummas, or localized lesions affecting the skeletal system, is found is which stage of syphilis
Tertiary (late) syphilis