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peripheral nervous system consists of
12 pairs of cranial nerves
31 pairs of spinal nerves
autonomic nervous sysetem
cranial nerves and the mneumonic
Oh, oh, oh, to touch and feel very good velvet, such heaven!
olfactory, optic, oculomotor, trochlear, trigeminal, abducens, facial, vestibulocochlear, glossopharyngeal, vagus, accessory, hypoglossal
central nervous system consists of
brain and spinal cord
the autonomic nervous system of the PNS consists of
sympathetic fibers and parasympathetic fibers
neurons are the…
basic unit of the brain, transports impulses/messages
motor vs sensory neurons
motor neurons impact mobility
sensory neurons impact perception and retain/processing of information
myelin sheaths
white lipid covering that enhance the speed of nerve impulse conduction along an axon
cerebral spinal fluid action, produced by
circulates/cushions brain and spinal cord
produced by choroid plexus
CSF circulation
circulates through subarachnoid space and is reabsorbed via arachoid villi to the suprasaggital sulcus
neuroglial cells action
position, structure, and nutrition for neurons
also help regulate the blood brain barrier
blood brain barrier
endothelial cells of cerebral capillaries keep substances in blood and out of CSF circulation/brain tissue
what cross the BBB
oxygen, Co2, glucose, water, alcohol, anesthesia
what does NOT cross the BBB?
larger molecules like albumin/any substance bound to it, some antibiotics
cerebral circulation
internal cartoid branches to 2 anterior cerebral arties and 2 middle cerebral arteies
r/l vertebral arteries join to make the basilar artery
the basiliar artery branches off into the two posterior cerebral arteries to form circle of willis
layers of brain
cerebral cortex, pia mater, subarachoind space (CSF!), arachnoid space, dura mater, cranium, scalp
3 main areas of the brain
frorebrain, cerebellum, brainstem
forebrain
most advanced
divides into cerebrum, diencephalon, thalamus, hypothalamus, epithalamus
cerebrum recieves info from the ____. Its three main functions are…
receives info via the thalamus
intelligene, creativity, memory
thalamus
in the diencephalon, switch board of CNS for sensory and LOC
epithalamus job
emotion, smooth movement, voluntary motor function
hypothalamus job
under ANS control to regulate temperature and cognition
Cerebral cortex
of the forebrain
composed of gray matter to control higher functioning, processes peripheral NS, feelings/thoughts
brain stem is composed of the
midbrain, pons, RAS, and medulla
responsible for basic life functions such as breathing, heart rate, and arousal
reticular formation system(RAS)
part of brain stem, controls alert/awareness
cerebellum function
recieves info about muscle, joints, tendons to regulate balance
anterior, posterior, and middle artery are joined together by small comunicating arteries to form a
ring at the based of brain called circle of willis
spinal cord regulates
mobility, organ function, sensory perception
transmits info to/ from brain
descending tracts of spinal cord- originate in…carries…
begin in brain and end in spinal cord
carries autonomic/involuntary movement
ascending tracts of spinal cord- originate in…carries…
begin in spinal cord and end in brain
carries sensation pain, temperature, light tough/pressure and awareness of movement
sympathetic NS- carries, cells originate, location
urgent stress response= fight/flight
cells originate in grat matter
nerves located T1-L2/3
what is the flight/fight response
increased HR, RR, inhihbits GI and repro
parasympathic nervous system
cells from S2-S4 and cranial nerves 3, 7 ,9, 10
can slow body down when needed
involves sensory and motor function= irritation, stretching of an organ, decrease in O2, pain perception
what is a bodily therapy that can control PNS
biofeedback
nursing assessment of neuro
fam hx/genetic risk= epilesy, stroke, mirgraines
personal hx= SUD, occupation, smoking, appearance, education
memory, attention, language/copying, cognition, cranial nerves, sensory function, relfex activity, cerebellar function (balance)
mental status assessment consists of
LOC and orientation/cognition
LOC
aawareness of self/environment
includes= A&O, amount of stimulation needed to arouse
ask= person(HCP), place(home address), time(year/month)
when should you NOT assess LOC?
if a pt was just medicated or if hypoglycemic
less than levels of alertness
lethargic= fades in/out, drowsy, slowed
stuporous= pt can only be awakened w vigorous or painful stim (sternal rub)
comatose= no arousal
What information from sensory assessment is key to baseline?
what is their preferred hand dominance
what does cognition assess
memory and attention
use cognition box= directions, reading comprehension, ease of ability to find words
glascow coma scale- what are the main areas w scoring and highest score?
eye opening (4) verbal response (5), motor response (6)
highest score is 15 (lower the score the lower the neuro functioning)

what other assessments are done with GCS? explain them
pupillary response- size are equal, reactivity to light, constriction
muscle strengths- hands/feet
when should we assess size of pupils?
before using flashlight when testing for constriction

decortication, score?
arms, wrists, fingers are flexed
internal rotation and plantar flexion of legs
score= 3
what could decorticate positioning mean?
potential lesions in the corticospinal pathway
Decerebration
abnormal movement, rigidity w extension of arms/legs
pronation of arms
plantar flexion
opisthotonus= body spasms, bowed forward
score of 2

motor response GCS
pt dosen’t respond to comands, either localizes (5), withdraws (4) OR…
abnormal flexion= decorticare posturing is a score of 3
abnormal extension= decerebrate posturing is a score of 2
Pupillary assessment= PEARRLA
pupil size, light, accomodation
light reactions= brisk, slugish, fixed, dilates, pinpoint
Lab assessment fo neuro abnormalities
BMP- Glucose, Calcium, Sodium, Potassium, Chloride, CO2, BUN Creatinine
ABG= pH
skull and spine xrays for assessing neuro system investigates
fractures, calcifications, erosions, structural abn
Cerebral angiography (arteriography) for assessing neuro system investigates
perfusion to the brain
potential brain bleeds/ruptured BV
CT scan for assessing neuro system investigates
bone and CSF abnormalities
MRI for assessing neuro system investigates
nerve roots/srtucutres
what other more rare assessments can we go for abn of neuro system
PET scans
single photo emission CT (SPECT)= crosses BBB
MEG= expensive, see brain singnals in action
electromyography (EMG)
identifies nerve/muscle disorders as well as spinal cord disease
lumbar puncture
insertion of spinal needle into subarachnoid space (3rd/4th lumbar vertebrae) to assess CSF for inf, bleeding, cancer, cranial pressure disorders
contraindicated in pt w increased ICP or skin infection near puncture site
lumbar puncture nursing interventions
stand at hob, ensure consent is given, answer questions
ask provider for calming meds, ensure admin of local anesthetic
position pt to fetal side lying (to seperate vertebrae for inc access to nerve roots)
ensure an empty bladder
teach pt to STAY STILL and alert if feel shooting pain/numb/tingling
monitor for s/s of comp= inc ICP, CSF leak, herniation, inf, hematoma
spinal h/a from lumbar pincture
due to the brain taking a while to replenish CSF
hard to treat
s/s of inc ICP
h/a, n/v, altered LOC, vision changes/blurred vision
follow up care from a lumbar puncture
lie flat, ensure bed rest
drink fluids
obtain VS within 1st hour, neuro checks Q1 hr for 3-4 hrs
assess site
CSF appearance
clear like water
EEG (Electroencephalography)
records electrical activity of cerebral hemispheres showing freq/amp
sleep deprivation may be required, pt cant drive home after
anticonvulsants can be witdtheld 12-24 hrs before
EEG (Electroencephalography) nursing maagement
ensure pt has not fasted (hypo can alter results), ensure hair is clean
ensure a quiet room w no visitors
pt can be in bed or in chair
lie still w eyes closed at first, then engage in activity like…
hyperventilation= show vasoconstriction/alkalosis which can initate seizure
bright light
sleep dep.
nursing post care of EEG
wash hair asap!
what is a seizure? what can it result in?
abnormal, sudden, excessive, uncontrolled electrical discharge of neurons w/in brain
can result in alternation of consciousness/sensory ability/behavior
epilepsy
two or more seizures
chronic disorder w recurrent, unprovoked seizure activity
can be caused by anormality in electrical neuronal activity/imbalance in neurotransmitters (GABA)
examaples of causes of seizures
fever
alcohol withdrawl
brain tumor
head injury
generalized tonic clonic seizures
lasts 2-5 minutes, stiffening, muscle rigidity, immediate LOC
postictal state of tonic clonic seizures
a period of confusion, disorientation, and fatigue that follows a seizure, lasting from minutes to hours.
partial/focal seizures
one part of the cerebral hempisphere, either complex or simple partial
complex partial seizures
may lose consciousness for few mins
amnesia after
simple partial seizures
less responsive to treatment
seen in adults
remain conscious, see aura
unclassified seizures can occur for
no reason
primary/idiopathic epilepsy
not associated w an identifiable brain lesion
secondary seizures
result from underlying brain lesion, most commonly a major trauma
many diseases/disorders associated w s/s of seizure
seizure risks
metabolic disorders
acute alochol withdrawl
electrolyte disturbances (Na2+, K+. hypoglycemia)
heart disease
high fever
stroke
substance abuse
head injury
seizure diagnoses
EEG
CT scan/MRI
rule out underlying causes, documentation before/after seizures
carbamazepine
tegratol
monitor WBC, can decrease
Diazepam and or Lorazepam
take at same time daily, follow up on labs
seizures given in hospital to stop (iv or rectal)
divalproex
depacote
monitor theraputic level
gabapentin
neurontin
for neuropathy
Lamotrigine
lamactyl
titrate doses, do not stop abruptly
monitor for SJS
Levetiracetam
Keppra
do not stop abruptly
Phenobarbitol
barbituate
decreases the effectiveness of hormonal contraceptives and interacts dangerously with alcohol
Phenytoin
Dylantin
IV/PO
don’t give with warfarin→ pt will bleed more
general anti epileptic therapy interventions
evaluate most current blood level of medication (theraputic range)
be aware of drug/drug interactions
maintain theraputic blood levels for max effectiveness
document/report adverse reactions
seizure precautions
airway= oxygen, suction equipment
IV access (ensure flushed Q shift)
side rails up, padded rails (some cases)
Do not force anything into mouth, (NO TONGE BLADE)
turn pt on side
protect from environment= clear, free of clutter
nursing management w seizure occuring
vs, o2 sat
document start/end time, ensure safety, NO RESTRAINTS
after 5 mins get ativan to stop seizure
other meds= lorazepam, diazepam, diastat, IV phenytoin
status epilepticus criteria
ER- prolonged seizures lasting more than 5 mins OR repeated seizures over course of 30 mins
status epilepticus managment
establish airway- suction PRN
ABGs
ensure safe environment= clear clutter
IV push lorazepam, diazepam, rectal dizepam
loading dose IV phenytoin

vagus nerve stimulation
device subcutaneously surgically implanted near collarbone in L chest wall to the vagus nerve to precent simple/complex seizures
other surgical mangement for seizures
anterior temporal lobe resection
partial corpus callostomy= cut brain fiber connecting 2 halves of brain
Patient/family education
alternative employment, refer to social services
vocational rehab
anti epileptic drugs may not be stopped even if seizures stop
no driving for 6 mos after a seizure