immunohematology

true

the testing of patient blood with potential donor is called compatibility testing or crossmatching

false

the three antugens of the ABO grouping are ABO

true

antibodies to antugens in ABO blood groups are naturally occuring

false

naturally occuring antibopdies to the Rh antigens are of the IgM class

false

there are 6 known antigens of the Rh system

packed cells

best sued when oxygen carrying capacity is needed

whole blood

rarely used but can meet a patients need for volume replacement, oxygen-carrying capacity, and heat-labile coagualtion factors

fresh frozen plasma

used to treat multiple coagulatio deficiences

monoclonal factor VIII

used to treat hemophilia

coombs

what is another name for anti-human globulin reagent

no

wgen ruling out cells on an antibody panel, are you abel to fully exclude a heterozygous antigen that shows dosage wuthouy furtegr inetrpretations

flase

antibody screens are used only to detect suspected antibodies of the BAO system

false

a clinically significant antibody in a 2 month old neonate is an antobody taht ajs been priduced by the neonate

three cells must be positive with antigen and three cells

what si rule fo 3

true

the dat helps determine if antoibody or compleem is bound to tge patients RBCs where the IAT is the basis for antobody screens and cross amtches

string, weaker

screeing cells may demonstarte dosage

patient serum, aptient cells

when performing an antobody panel, what does the autocontrol consist of

to evrify that AHG was added that teh reagent is working

what is te purpsoe of check cells and how are they sjued in antibody panel testing

false

one must ooen a unit of blood to screen for possibel immunologicla testing suchas HIV, etc.

allele

vareibts of a gene and trait

tarnfusion emdicine

the procedires involved in collecting, storing, oprocessingab distributing blood and ist components

RBC and plasma

the technoque of replacing wjole blood

genotupe

actual genetic makeuo may nto be evident by direct teets

immune antibodt

eunexcpected antibodies that result form specific anyigenic stimulation

phenoyu[pe

RBC type as determnined by direct tests

immunohematology

the technoqies and prodedures uvolving the stufy of ummunologic resoibses of blood RBCsand their related components, focusing on blood group antigens and antibodies.

does the patient serum contain an antibody against the donors RBC

when blood is to be transfused the most imprtant consideration

D

patiensta re geenrally described as Rh positibe or Rh negatibe based on the rpesence of which of the folloiwng antigens on rhe RBCs

false

HDFN most often occurs due to an ABOP incompativility and results ina severe disease state

true

when NDFN occurs due ro an incomapibility mom is usually O blood type and the babt us eiter A or B from the fatehr

false

When HDFN does occur it is usually due to unconjugated bilirubin that doe snot cross the blood braun barrierand can lead to jaundice in newborns, affecting their overall health.

true

the antigens of the ABO blood group are sugars whiele the antigens of tghe Rh blood group are proteins

are generally Ig G rather than Ig M

Immune A and B alloantibodies differ from naturally occurinhg A and B alloantibodies in that they are usually formed in response to transfusion or pregnancy. This results in a more significant immune response.

A patient is very old ro young

An ABO discrepency between forward and reverse grouping maybe best explained by

clerical arrors or a smaple mix up

26 yo pregant woman

AA, AB, AO BO

genotypes

A, B, AB

phenotype

A-

BC

O positive

DB

on serum suspectred of containing antibodies

IAT

on RBCs suspected of beig coated wot antibody

DAT

major iuncompatibility between patent and donot

cross matcing of donors RBCs with the patients serum culd demostarte

antibodies to rare antigens, patient antibodies to varous nonslef antigens

tetsting of the aptunets serum with a panel group O cells for unexcpected antobodies can demonstarte

the grratets exposure of the motger to the babys RBCs with D antigens is during labor and delivery

HDFN does not usually occur in the first pregancy if the mother us D negatuve and the baby is D posuguve

blood group incompatibility

probable caus eof infant jaudice

ABO compatibility between mother and babu

whatw a sthe msot likely diagnosisfor hemolytic disease of the newborn (HDFN).

mix up of patinet sepcimens

probable cuas eif incompatible crossmatch

immediate gemolytic

what tyoe of transfuson die the patient experiencereaction during a blood transfusion that occurs within 24 hours, usually due to ABO incompatibility.

renwed rapid broductu=ion ofan antibody following second or later contact

what is an anamestic repsonse in immunologicla repsonsethat leads to a quicker and stronger antibody production against previously encountered antigens.

false

ohne

flase

in hdfn rh incomoatibility btween mother ad chidl=kd is suually mila and ABo incompatibilitu is usually kuife rhreatenung

true

rh incomaptibility is preventabekla nd rpedicatable

false

cold reacting antiboduesare clinically significant

true

un a crossnnatch a positive reactin is agglutination

true

if an auto cntrol is oositive the oatines antibodues may be reacing with the patents cellsThis suggests that the patient's antibodies could be interacting with their own red blood cells.

autoantibodies

when all rhe screening cells react at the same phase and strength you should suspect