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what is the skeleton made of?
bones & cartilage
are bones living organs?
yes bones are living organs
how many bones are in the adult human body
206 bones

label the bones
Clavicle – C
Cranium – A
Femur – F
Humerus – D
Metacarpals – E
Patella – G
Sternum – B
Tarsals – H
what kind of tissue is the bone?
connective tissue
what is the bone’s matrix called?
osteoid
definition of axial skeleton
bones on or near the midline
definition of appendicular skeleton
bones away from midline
limbs & bones that attach limbs to the trunk
axial or appendicular? - carpals
appendicular
axial or appendicular? - lumbar vertebrae
axial
axial or appendicular? - cranium
axial
axial or appendicular? - scapula
appendicular
axial or appendicular? - radius
appendicular
axial or appendicular? - femur
appendicular
axial or appendicular? - mandible
axial
axial or appendicular? - pelvis
appendicular
axial or appendicular? - sternum
axial
axial or appendicular? - ribs
axial
what are the 7 functions of the bone?
support
protection
anchorage
mineral storage
blood cell formation
fat storage
hormones production
skeleton function: support
bones provide a framework that supports the body
skeleton function: protection
skull - brain
vertebrae - spinal cord
ribcage - heart, lungs
skeleton function: anchorage
skeletal muscles attach to bones by tendons, using bones as levers to move the body
skeleton function: mineral storage
bones are reservoirs for calcium & phosphate
bones release these minerals into bloodstream as needed
skeleton function: blood cell formation
hematopoiesis (blood cell production) occurs in red marrow
skeleton function: fat storage
fat is stored in the yellow marrow inside long bone
skeleton function: hormones production
bones produce osteocalcin, a hormone that helps with many body processes
what are the 5 types of bones? provide examples
Irregular bones: ex. Vertebrae
Long bones: ex. Femur, finger bones
Flat bones: ex. Sternum, ribs
Short bones: ex. Wrist & ankle bones
Sesamoid bones: form within a tendon; ex. patellae
how many long bones are there and what are they?
9 long bones
humerus
radius
ulna
metacarpals
phalanges
femur tibia
fibula
anatomy of long bone: articular cartilage
Art: at joints
Protects ends of bones from wear
anatomy of long bone: proximal epiphysis
knobby end of bone closer to trunk
anatomy of long bone: distal epiphysis
knobby end of bone further from trunk
anatomy of long bone: diaphysis
shaft of bone
anatomy of long bone: epiphyseal plate
growthplate
made of cartilage which ossifies and regrows repeatedly
anatomy of long bone: spongy bone
makes up inside of epiphyses
full of red marrow
anatomy of long bone: compact bone
makes up diaphysis and outside of bone
anatomy of long bone: red marrow
filled with stem cells
creates blood
anatomy of long bone: medullary cavity
hollow space in diaphysis
full of yellow marrow
anatomy of long bone: yellow marrow
stores fat
anatomy of long bone: periosteum
“around-bone”
CT layer lining the outside of a bone
anatomy of long bone: endosteum
“inside-bone”
layer lining the medullary cavity
anatomy of long bone: nutrient foramen
small hole for blood vessel to enter and exit bone
what are the four types of bones cells?
osteogenic, osteoblasts, osteocytes, osteoclasts
define the word roots: osteogenic
osteo = bone
gen = produce
what are osteogenic cells? where are they located?
stem cells
located in periosteum and endosteum
osteogenic cells are the only bone cells to do what?
only bone cell that does mitosis
osteogenic cells divide to form what?
osteoblasts
define the word roots: osteoblasts
osteo = bone
blast = bud/sprout
function of osteoblasts?
build new cells
make bone’s matrix (osteoid) - calcium + collagen + water
osteoblasts get trapped and become what?
osteocytes
where are osteoblasts located?
on the periosteum and epiphyseal plates. makes sense becs bones grow longer at the epiphyseal plates and grow wider along the periosteum
define the word roots: osteocytes
osteo = bone
cyte = cell
what are osteocytes? where are they located?
mature bone cells
located in compact bone and spongy bone
what do osteocytes perform?
perform daily functions of bone
define the word roots: osteoclasts
osteo = bone
clast = break
function of osteoclasts? where located?
clean away bone
located on periosteum and endosteum
when are osteoclasts used?
during fx repair and bone growth (clean away old bone from the medullary cavity)
What is the skeleton made of before it is bone?
Cartilage
“endo” means __
inside
“chond” means __
cartilage
“os” means __
bone
“fication” means __
making
Endochondral Ossification means __
inside cartilage bone making
what is Endochondral Ossification? when does it start?
The formation of bone from cartilage
starts in the embryo
What are cartilage cells called?
chondrocytes
Which type of bone cell builds new bone?
osteoblasts
Which type of cell forms when osteoblasts become buried?
osteocytes
Which type of bone cell cleans old bone?
osteoclasts
what is step one of Endochondral Ossification?
cartilage model forms
when does step 1 of Endochondral Ossification occur?
starts 6-8 weeks after conception
what is created in step 1 of Endochondral Ossification?
Chondrocytes are created to form a “model” of where the bone will eventually be
The “model” is made of hyaline cartilage
what is step 2 Endochondral ossification?
perichondrium & periosteum
describe step 2a of Endochondral ossification
A perichondrium (membrane around the cartilage) forms around the “model”
describe step 2b of Endochondral ossification
The perichondrium turns to - bone and is now called the periosteum
Cut off from nutrients by the periosteum, the chondrocytes on the inside start to die and are replaced by bone.
what is step 3 of Endochondral ossification?
primary ossification center
describe step 3 of endochondral ossification
Blood vessels enter the center of the diaphysis, forming the primary ossification center (where ossification of the diaphysis begins)
With ingredients from the blood, osteoblasts begin building osteoid in the primary ossification center.
Ossification of the diaphysis occurs from the inside-out, starting at the primary ossification center and extending toward the ends of the bone.
what is a crucial ingredient in osteoid?
calcium which is delivered by blood vessels
what is step 4 of endochondral ossification?
medullary cavity
describe step 4 of endochondral ossification
Osteoclasts clean away some newly formed bone in the diaphysis, forming the medullary cavity
what is step 5 of endochondral ossification?
secondary ossification centers
describe step 5 of endochondral ossification
Around the time of birth, blood vessels enter the epiphyses, forming the secondary ossification centers (where ossification of the epiphyses begins)
With ingredients from the blood, osteoblasts begin building osteoid in the secondary ossification centers
Ossification of the epiphyses occurs from the inside-out
what is step 6 of endochondral ossification? describe it
ossification is complete
The only cartilage left at the end of endochondral ossification is the articular cartilage and the epiphyseal plates
partial bone fx
break that doesn’t go through the bone completely
complete bone fx
break that goes completely through the bone
open bone fx
bone goes through skin and can be seen on outside
closed bone fx
fx does not break skin, aka simple fx
non-displaced fx
two broken ends of bone are still ined up and have not moved out of place
displaced bone fx
two broken ends are not lined up and are moved out of place. need to be set
transverse bone fx
breaks that occur in a straight line across the bone
oblique bone fx
breaks occurs at a diagonal angle
greenstick bone fx
occurs in children; partial fx that caused bone to bend
impacted bone fx
broke ends of bone are jammed together by the force of the injury
communicated bone fx
bone broke into at least 3 pieces w/ many fragments at fx site
segmental bone fx
same bone broke in 2 places, causing a “floating” segment of bone between the two breaks
what does treatment of a fx start with?
reduction
what is reduction and what are the different kinds?
reduction: realignment of broken ends
closed (External) reduction: doctor’s hands set the bone back into alignment
open (internal) reduction: surgery is required to secure ends of bones together with screws and plates
how long does the average-sized bone take to heal?
6-8 weeks, longer for larger more mature bones
describe step 1 of fx repair

describe step 2 of fx repair

describe step 3 of fx repair

describe step 4of fx repair
