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22 Terms

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Acute Coronary Syndromes (ACS)

Includes unstable angina and myocardial infarctions (MIs), characterized by plaque rupture, thrombosis, and inflammation.

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Myocardial Infarction (MI)

A condition involving myocardial cell death, leading to the release of troponin into the bloodstream.

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Unstable Angina

A type of ACS without troponin rise, characterized by chest pain that may be spontaneous and severe.

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STEMI

ST-elevation Myocardial Infarction, indicated by the presence of ST-segment elevation on an ECG.

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NSTEMI

Non-ST-elevation Myocardial Infarction, characterized by elevated troponin levels but without ST-segment elevation.

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Risk Factors for ACS

Non-modifiable: age, gender, family history. Modifiable: smoking, hypertension, diabetes, obesity.

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Troponin Levels

Proteins released into the bloodstream when myocardial cells are damaged, crucial for diagnosing myocardial injury.

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ECG Changes in MI

ST elevation, T-wave inversion, pathological Q waves, and may show non-specific changes or be normal.

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Silent MI

Myocardial infarction without typical chest pain, more common in elderly and diabetic patients.

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Management of STEMI

Requires urgent revascularization via PCI (Percutaneous Coronary Intervention) or CABG.

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Management of NSTEMI

Involves serial troponin testing and treatment based on risk assessment.

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Complications of MI

Include cardiac arrest, left ventricular failure, bradyarrhythmias, and pericarditis.

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CABG Indications

Coronary Artery Bypass Grafting indicated for left main stem disease, triple-vessel disease, or refractory angina.

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Role of Antiplatelets in ACS

Aspirin and a second antiplatelet agent are administered for at least 12 months to reduce vascular events.

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Diagnosis Criteria for ACS

Increased cardiac biomarkers alongside symptoms of ischaemia or notable ECG changes.

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Common Signs of ACS

Distress, anxiety, pallor, sweatiness, abnormal pulse or blood pressure.

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Symptoms of ACS

Acute central chest pain lasting more than 20 minutes, potentially with nausea, sweating, and dyspnoea.

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Differential Diagnosis of ACS

Includes stable angina, pericarditis, myocarditis, and aortic dissection.

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Risk Factor Management

Includes smoking cessation, diabetes management, dietary changes, and promoting exercise.

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Troponin Testing Timing

Troponin levels should be checked at specific intervals (e.g., two samples 3 hours apart) for accuracy.

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Mental Health Considerations

Depression and anxiety are correlated with poor cardiovascular outcomes and should be managed accordingly.

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Evidence for Patient Education

Patients should understand their condition, symptoms to watch for, and the importance of follow-up care.