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What is self care and what does it involve?
it is the diagnosis, treatment and prevention of one’s own illness
it involves full spectrum of care: prevention, wellness stratgeties, diagnosis, screening, measures for treatment and relief
PPCP with self care
Collect, Asses, Plan, Implement, Follow up
QuEST
Quickly assess
Establish self care appropriatness
Suggest care
Talk to patient
SCHOLAR-MAC
Symptoms
Characteristics
History
Onset
Location
Aggravating Factors
Remitting Factors
Medications
Allergies
Conditions
Exclusion for self treatment
is symptom is beyond scope, health status, history, nonprescription is not indicated, previous failure with nonprescription drugs
Refer patients when
too severe symptoms, minor but persistant and not identifiable, repeatedly returned, pharmacist is in doubt about the condition
Type 1 Diabetes Risk factors
genetic, autoimmune, white race, environmental factors
Type 2 Diabetes risk factors
non modifiable: age>35, race(other than white), fam hx, hx of gestational diabetes, PCOS
modifiable: obese(>25kg/m2), no activity, HTN(>130/80), dyslipidemia, prediabetes, smoking, MASLD
What are the complications with diabetes
Heart disese, neuropathy, retinopathy, CKD, stroke
emerging: cancer, liver disease, infections, cognitive/functioning ability
Preventative measures for diabetes complications
routine exams, glucose monitoring, skin/dental/eye care, BP management
Treatment goals for adults with diabetes? A1c, BP, Lipids, smoking
ADA:
<7% for most adults
preprandial: 80-130mg/dL
2-hr postprandial: <180mg/dL
AACE
<6.5%
<110mg/dL prepran
<140 post pran
BP:<130/80
Lipids: treatment and stating dose based on risk stat
smoking cessation
Ketone testing indications
indicated for poor glycemic control in patients who are prone to elevated ketone levels
acute illnes, BG>240mg/dL, symptoms of DKA(fruity breath, klussmaul breathing, thirst)
ketone testing methods
urine
inexpensive, eh accuracy, positive test: if test trip changes after dip
blood
expensive, accurate, postive test >0.6mmol/L
CGMs perals
monitors glucose levels 1-5 min
helps reduce hypoglycemic events, lowers A1c, quick detection, and help see trends in glucose levels and habits
T1DM dosing and insulin
need both bolos and basal
0.3-0.5units/kg
50% bolus, and 50% basal
1 unit covers 10-15 grams of carb
T2DM dosing and insulin
start with basal first, then add others
0.5-1.2units/kg
1 unit = 0.1mL
Insulin Injection Devices advantages
Ease of use, dexterity, convenience, easy/accurate dosing, privacy
Insulin Injection Devices disadvantages
units per pen/vial, varying exp. dates, limited units per admin, cost
Which injection site has good absorption?
lower abdomen
pick one and dont switch
Factors influencing insulin absorption?
location: Abdomen > arm > thigh > buttock
depth: IV > IM > SQ
IV is avoided tho
increase: Exercise, Massaging the injection site
decrease: Cold skin temperature, Smoking
Hypoglycemia symptoms + treatment
sweating, trembling, Tachycardia/Palpitations, Confusion/Tiredness
Treatment: Rule of 15
give 15g of carbs, if its still less than <60 after 15 min, give 15g more carbs
equivalent: 3 tsp on sugar, 4 ounces of juice, 5-6lifesavers or 8 ounces of milk
Indications for aspirin for diabetes
if hx of ASCD
or if none
70<x>50—> ASCVD risk factor(HTN, DysLd, smoking, CKD,fam hx)
Where do infants get their macronutrients from?
Carbs: mainly lactose
Protein: whey and caseinate salts
Fat: Linolenic acid (omega-3 fatty acid), Linoleic acid (omega-6 fatty acid)
Breastfeeding recommendations
untl 4-12 months of age, atleasy 6 months when possible
if stopped before 12 months, make sure to give iron fortified milk and NOT cows milk
Breastfeeding Warnings and Contraindications
CIs:
• Lactation suppressors: bromocriptine
• Chemotherapy: cyclophosphamide, doxorubicin, methotrexate
• Immunosuppressives: leflunomide, cyclosporine
• Ergotamine, lithium, phenindione, and generally drugs of abuse
Not recommended if uncontrolled HIV or infants with galactosemia
Infant formula indications
Substitute—> when cant breastfeed or CI to it
Supplment—> Infants who inadequately gain weight
Polymeric vs Monomeric Formulas
Polymeric→ standard, protein remains intact, need fully functioning GI tract to digest
Monomeric→ for abnormal GI tracts, Proteins are partially or fully hydrolyzed
Gerber Good Start® Indication + components
Infants with intolerance (not allergy) to milk- based formulas
Lactose + Partially hydrolyzed whey, vegetable oils
Similac® Total Comfort/ Sensitive Indication + components
Both: Infants with lactose malabsorption or intolerance
Sensitive: + fussiness and gas
Both components: Milk protein isolate (whey + casein), vegetable oil
Comfort: Corn syrup solids
Sensitive Corn syrup solids + Lactose free but contains sucrose and corn maltodextrin
Enfamil® Gentlease Indication + components
Infants with fussiness and gas
Partially hydrolyzed whey, lactose, vegetable oil
Goat milk indication + components + supplements
Intolerance to cow’s milk
Lactose, Whey +/- casein, Medium and short chain fatty acids
Requires iron, vitamin D and folic acid supplementation
Soy-Based Formulas Indications + CIs
Lactose deficiency or intolerance
Galactosemia
Cow's milk protein allergy
Vegetarians
preterm babies, CF babies, Prevention of colic or allergy or if developed protein induced enterocolitis
Sucrase-Isomaltase Deficiency recommendation
Similac® Soy Isomil OR Enfamil® ProSobee
bc sucrose free
Who should receive premature formula + what is different in it?
Preterm infants (born <36 weeks gestational age) weighing less than 2-3 kg
less lactose, more protein, vitamins(A,D,E), other stuff
Casein Hydrolysate Based Formula indication
Infants sensitive to intact milk proteins
Casein Hydrolysate Base Formula Pregestimil® and Alimentum® indication
Malabsorption
• Short-bowel syndrome
• CF
• Bilary atresia
• Fat malabsorption
• Chronic diarrhea
• Food allergies
Iron-fortified
Casein Hydrolysate Base Formula
Portagen® Indication
Infants unable to absorb/digest fat
• Fat malabsorption
• Intestinal lymphatic anomalies
• Chronic liver disease
Casein Hydrolysate Base Formula
Nutramigen® indication
Only indicated for infants with food allergies
Amino Acid Based Formulas Indications
Extreme milk protein allergy
Extreme soy allergy
Extreme food allergies
Modular Nutrient Components Products: Carbs, Protein, Fat, Carb + Fat, Protein + Fat, DHA/ARA
Carbs: Polycal®
Protein: Beneprotein®, Complete and Essential Amino Acid Mix, Liquid Protein Fortifier, Procel®
Fat: Liquigen®, MCT Oil, Microlipid®
Carb + Fat: Duocal®
Protein + Fat: Benecalorie®
DHA/ARA: Enfamil® DHA & ARA Supplement
Ashwaganda indication + DDIs
reduces anxiety, stress and may improve insomnia (possibly effective)
DDIs: Antidiabetes drugs, Thyroid Hormones
Level of Evidence for Drug Drug Interactions (A,B,C,D)
A: high quality data for the DDI
B: study but its not that great for DDI
C: consensus and expert opinion DDI
D: anecdotal, in vitro, Theoretical based evidence
Vitamin D indication + DDIs
builds up bone and supports muscle, Osteoporosis, Deficiencies
DDIs: Atorvastatin, Diltiazem, Verapamil
St John’s wort indication + DDIs
Mild to Moderate Depression Symptoms, Menopause symptoms
DDIs: (B level)Contraceptives, Omeprazole, Warfarin, Imatinib(A)
Prebiotics moa, benefits, clinical applications
“Food for your Good Bacteria”
Non-digestible fibers that act as food to foster a favorable environment for beneficial bacteria to grow
Benefits: decreases constipation, reduce triglycerides, better absorption of calcium and magnesium
good for ppl on low fiber diets and to support metabolic/ immune health
Probiotics moa, benefits, clinical applications
“Good Bacteria for your Gut”
Live, beneficial bacteria that can improve gut health
Reduce colonization caused by pathogenic organisms
Benefits: induce production of cytokines, enhance antiviral activity, Inhibit pathogens
Indications: IBD, Eczema, DM, IBS, infection
Protein supplements products and how its different
Whey concentrate: higher levels of fat, lactose and carbs; cheapest
Whey isolate: leanest powder >90, amino acid profile, lactose and fat free
Whey hydrosalate: predigested 80-90% protein content
Caffeine info + safety concerns + counseling
CNS stimulant (preggo should avoid)
100% F
basically restlessness, heart stuff
400mg or less is safe
Insomnia clinical presentation
difficulty sleeping, unusual or troublesome dreams, > 30 mins to fall asleep, < 7 hours of sleep per night
chronic: >3months with >3 times per week
Moisturizer vs Hydrocortisone
Moisturizer are maintenance/barrier therapy, hydrocortisone treats inflammation and flare of AD
Common Moisturizer Ingredients
Humectants: draw water into the strateum corneum
Emollients: Fills spaces between skin cells and soften skin
Occulsives: reduce transepidermal water loss
How is a shampoo used?
Massage into scalp and leave on for 3-5 min; use daily for 1 week and then 2-3x weekly for a couple weeks, followed by once weekly
Dandruff treatment
non medicated shampoo—> cytostatic agents(zinc, sulfide)→ ketoconzole, coal-tar shampoo
Contact dermatitis vs allergic + treatment
contact: caused by an irritating substance (hx of repeated exposure)
treat with removing irritant, the soothe and repair the skin barrier
allergic: caused by skin reaction to an antigen
remove allergen, hydrocortisone, calamine lotion
Diaper Dermitis treatment
Zinc oxide active ingredient
Pharmacological Treatments of Urushiol
topical steroids for the inflammation
oral antihistamines for helping sleep at night
how to apply skin protectants
apply a thick layer and dont rub it all in