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tissue
group of cells with similar structure and function
epithelial tissue
protect, secret, absorbs; widespread throughout the whole body
avascular
nourished by underlying connective tissue (no blood vessels)
Simple Squamous
single thin layer, flattened cells that are packed tightly together (diffusion and filtrartion)
location: line alevoli of lungs, lines blood vessels, forms serous membranes that cover organs
Simple cubodial
single layer of cube shaped cells (secretion and absorption
location: walls of kidneys, lines ducts, and covers ovaries
simple columnar
function (ciliated): propels mucus or reproductive cells
function (nonciliated): secretion and absorption
location: digestive tract and mucus membranes that line body cavity
Pseudostratified columnar
cells vary in length, most contain cilia (absorption, secretion, propelling mucus)
location: respiratory tract, lining trachea
stratified squamous
function: protective covering where friction is common
location: lining of skin, mouth, esophagus, vagina, and anal canal
stratified cuboidal
many layer of flattened cells (protective covering where friction happens)
location: lines duct of mammary gland, sweat glands, salivary glands, pancreas and ovarian follicles
stratified columnar
surface cells are columnar and cells underneath vary in size and shape (protection, secretion)
location: lines male urethra, lines large gland ducts
transitonal
designed to stretch and then return to normal size (stretchability, protection)
location: lining urinary bladder, urethra, and ureters
glandular tissue
function: produces and secretes substances into ducts or bodily fluids
endocrine gland
ductless, secretions (hormones) diffuse into blood vessels (thyroid, adrenals, and pituitary)
Exocrine gland
secretions empty through ducts to the epithelial surface (sweat, oil, liver, internal and external glands)
merocrine
releases secretions by exocytosis (pancreas, salivary glands, sweat glands)
apocrine
pinch off portions of their cell bodies during secretions (mammary glands)
holocrine
release entire cells that disintegrate to release their secretions (oil glands)
connective tissue
throughout the whole body, bind body tissues together
fibroblast
stays in tissue for a long time, secretes fibers
mast cells
stays in tissue, releases heparin and histamine
macrophage
function as phagocytes, defends against infection and foreign particles
collagen (white) fibers
fibroblast, hold structures together (tendon, ligaments)
elastic (yellow) fibers
fibroblasts, stretchy and adds flexibility (vocal cords)
reticular fibers
fibroblasts, thin collagen fibers that provide delicate support (spleen)
areolar tissue
found underlying all epithelial tissues and functions to hold organs in place (between muscles, forms lamina propria)
adipose tissue
functions as a heat insulator and located in the subcutaneous layer below the skin (surrounds kidneys, behind eyeballs, between muscles)
reticular tissues
loose connective, forms framework for some internal organs (liver, spleen)
dense connective tissues
binds body parts (tendons, ligarments, white layer of eyeball)
hyaline cartilage
forms the larynx and costal cartilage that attaches ribs to sternum (larynx, attaches ribs to breastbone, epiphyseal plates)
elastic cartliage
supports, protects, provides flexible framework (framework for external ears, larynx)
fibrocartliage
supports, protects, provides basic framework (intervertebral discs, knees, pelvic girdle)
blood
composed primarily of fluid and transports nutrients and respiratory gases throughout the body (produced by red bone marrow)
skeletal muscle tissue
attaches to bones to produce body movement, under voluntary control, producing facial expressions (attached to skeleton)
smooth muscle tissue
involuntarily controlled, moves food through digestive system (digestive tract, blood vessels, urinary bladder)
cardiac muscle tissues
found in the heart, involuntary control (visceral organs)
nervous tissue
function: receives and transmits electrochemical impulses
location: brain, spinal cord, nerves
serous membrane
lines body cavities not open to the outside, simple squamous epithelium with an underlying layer of areolar connective tissue (pleura, pericardium, peritoneum)
mucous membrane
lines cavities that are open to the outside of the body, moist membrane, stratified squamous/simple columnar (oral/nasal cavities)
cuatneous membranes
skin, superficial epidermis
synovial membranes
lines fibrous capsules surrounding joints, composed of entirely connective tissues
hyperthermia
response to excess heat, sweat glands activated (extreme cases: fatigue, confusion, loss of coordination)
hypothermia
response to excess cooling, shivering (extreme cases: weakness, dizziness, irregular heatbeat)
layers of epidermis
corneum, lucidum, granulosum, spinosum, basale (come let’s get sun burned)
stratum corneum
outermost layer, composed of dead keratinocytes (make keratin), sheds
stratum lucidum
found in thick, hairless skin (palms, soles), composed of dead keratinocytes
stratum granulosum
composed of flattened keratinocytes
stratum spinosum
keratinocytes become flattened
stratum basale
innermost layer, cells undergo mitosis, contains melanocytes (make melanin)
melanin
pigment produced by melanocytes, found in stratum basale, provides protection against UV radiation
epidermis
superficial layer, skin color: genetic, environmental (uv radiation), physiological (blood circulation in blood vessels), diet and disease (carotene pigment found in yellow vegetables)
dermis
consists of (areolar and dense connective tissue, blood vessels, nerves, sensory receptors, hair follicles, sebaceous and sweat glands)
hypodermis
not part of the skin, binds to skin underlying organs, composed of areolar and adipose tissue, contains major blood vessels that supply skin
nails
protective covering, composed of free edge, body, root
nail plate
overlies nail bed
lunula
actively growing region of the nail root
nail folds
overlap the edges of the nail
hair
found in everywhere (except nipples, external genitalia), composed of dead keratinized epithelial cells, hair follicles have an arrector pili muscle attached
sebaceous glands
secrete sebum (oil), all over body except for palms and soles
sudoriferous glands
secretes sweat, eccrine: responds to temp, apocrine: responds to fear, emotion, pain, sexual arousal
modified apocrine glands
ceruminous glands: secretes ear wax, mammary glands: secretes milk
inflammation (wound healing)
blood vessels dilate, clotting (proteins, oxygen, and immune) cells go to the area, blood clot forms
granulation tissue forms (wound healing)
growth of new capillaries, fibroblasts create collagen to bind wounds together, phagocytes remove debris and dead cells
regeneration of surface epithelium (wound healing)
scab protects damaged region, scab comes and tissue is reformed
wound healing
tissues that regenerate easily (epithelial tissue, fibrous connective tissue), tissues that regenerate poorly (skeletal muscle), tissues that are replaced w/ scar (cardiac, nervous)
burns
results in loss of body fluids and invasion of bacteria
rules of nines
determines extent of burns, body is divided into 11 area, each is (9%), genitals are (1%)
first degree burns
partial thickness burn, damage to epidermis, red and swollen skin (suburn)
second degree burns
partial thickness burn, damage to epidermis and upper dermis, red with blisters (stovetop burn)
third degree burn
full thickness burn, destroys entire skin layer, requires skin grafts, burn is gray/black (fire)
critical burns
over 25% of the body has second degree burns, over 10% has third degree burns
basal cell carcinoma
most common type, least malignant, arises from stratum basale
squamous cell caricoma
sun induced, curable, metastasizes to lymph nodes if not removed, arises from stratum spinosum
malignant melanoma
most deadly, metastasizes to lymph nodes and blood vessels easily, detection uses ABCD rule
A rule
asymmetry (two sides do not match)
B rule
border irregularity (borders of the mole are not smooth)
C rule
color (different colors in pigmented area)
D rule
diameter (spot is larger than 6mm in diameter)
epiphyseal line
seen in growing children, turns into line when older
osteocytes
situated within cavities known as lacunae
canaliculi
forms transport system that connects osteocytes to through the bone marrow
intramembranous ossification
boones develope from sheet like layers of connective tissue, includes bones of the skull and clavicles
endochondral ossification
formed from a hyaline cartilage model, includes majority of bones except bones of skull and clavicles
bone remodeling
3-5% of bone calcium are exchanged each year, occurs because of blood calcium levels& pull of gravity and muscles on the skeleton
parathyroid hormone (PTH)
released when blood calcium levels are low, activates osteoclasts, bone is broken down and calcium is released in the blood
calcitonin
released when blood calcium levels are high, activates osteoblasts, calcium is deposited into bone
factors affecting bone developement
nutrition (vitamin D), hormones (growth and sex), physical exercise
closed fracture
simple, break does not penetrate skin
open fracture
compound, break penetrates skin
reduction
realignment of broken bone ends (closed and open)
immobilization
cast or traction
Skeleton
axial (80 bones), appendicular (126)
paranasal sinuses
hollow portions around the nasal cavity, function: lighten the skull, amplify sounds made as we speak
hyoid bone
only bone that does not articulate with another bone, serves as a moveable base for tongue, allows for swallowing and speech
synarthroses
immovable joints
amphiarthroses
slightly moveable joints
diarthroses
freely moveable joints
fibrous joints
composed of dense connective tissues, immovable (skull)
cartilaginous joints
composed of cartilage, immovable or slightly movable (between first ribs and sternum)
synovial joints
composed of a complex structure, freely movable
endomysium
encloses a single muscle fiber (inside)