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Organic Compounds
▪ Always contains CARBON
▪ Contain C–H (carbon–hydrogen) bonds
▪ Sugar (C6H12O6), Linoleic Acid (C18H32O2), DNA, Alanine (C3H7NO2)
Inorganic compounds
▪ Usually do NOT contain carbon
▪ Rarely contain C–H bonds
▪ Salt (NaCl),Water (H2O),Muriatic Acid (HCl)
MONOMER
Small molecule that serves as the building block of a polymer
POLYMER
long molecule consisting of similar or identical monomers linked by covalent bonds.
METABOLISM
the sum of all chemical reactions that
happen inside a living organism to keep
it alive
Two types: Catabolism & Anabolism
CATABOLISM
▪ Process involves the breakdown of
molecules to release energy (complex
molecules into simpler ones)
▪ biomolecules are broken down to
release energy
▪ Breakdown of polymer into monomer
Example:
▪ Breakdown of food in the stomach for
the nutrients to be absorbed into the
blood vessels
ANABOLISM
▪ process requires and consumes energy
to allow the building processes to
proceed (builds complex molecules
from simpler ones)
▪ In anabolic reactions, our bodies use
simple chemicals and molecules to
synthesize (or build) biomolecules.
CARBOHYDRATES
▪ Most abundant of all organic
compounds and well–known as a
great source of energy
▪ Elements: Carbon (C), Hydrogen
(H), Oxygen (O) with a [1:2:1 ratio]
▪ Monomer: monosaccharides
▪ Polymer: polysaccharides
Examples:
▪ Fruits, bread, vegetables, rice, pasta
MONOSACCHARIDES
▪ Simple sugars with only one sugar
unit
▪ They are identified based on the
number of carbon atoms they are
made up of
▪ Highly soluble in water
▪ Building blocks of complex
sugars (carbohydrates)
Note: The suffix “-ose” means “sugar”
DISACCHARIDES
▪ Complex sugars made up of two
monosaccharides joined together
through a process called
condensation reaction or
dehydration synthesis
▪ a molecule of water (H2O) is
released when the two
monosaccharides bond
DEHYDRATION SYNTHESIS
▪ “condensation reaction”
▪ Water is removed when two
molecules combine to form a larger
molecule
▪ Anabolic reaction (builds up
molecules)
HYDROLYSIS
▪ Reverse of condensation reaction
▪ Adding water to a large molecule to
break it down into smaller molecules
▪ Catabolic reaction (breaks down
molecules)
Maltose
Glucose + Glucose
Found in Malt (germinated barley that has been baked and ground)
Lactose
glucose + galactose
found in milk and used in infrant formulas
Sucrose
Glucose + Fructose
common table sugar; most abundant disaccharide found
POLYSACCHARIDES
▪ Complex sugars made up of chains or branches of monosaccharides formed by condensation reaction
▪ capable of acting as energy storage or structural molecules as parts of cell structures
Examples:
▪ Storage polysaccharides – Starch
and Glycogen
Starch
Main carbohydrate
reserve in plants
Cellulose
– Found in the cell walls
of plants. Also gives fiber.
Glycogen
Main polysaccharide
of the body; Stored in liver
Chitin
structural polysaccharide
in outer coverings of crustaceans,
mushroom s and spider web
Amylose
linear structure;
straight chain
Amylopectin
Branched
structure; More soluble in
water
Amylase
– enzyme that breaks down
starch (amylose) into simpler sugars.
Found in saliva and pancreatic juice.
LIPIDS
▪ Biomolecules containing hydrocarbon chains, which serve as
long-term energy storage, insulation of your body, and makes up the cell membrane.
▪ Water-insoluble (hydrophobic)
▪ Elements: Carbon (C), Hydrogen
(H), Oxygen (O)
▪ Monomer: Glycerol and fatty acids
▪ Polymer: Do NOT include true polymers; not big enough to be considered macromolecules
Examples:
▪ Fats, oils, steroids, phospholipids,
and waxes
Glycerol
▪ It serve as the backbone of lipid
molecules.
▪ It is a three-carbon alcohol with
three hydroxyl (-OH) groups that
acts as a scaffold to which fatty
acids attach
▪ Has a structure of propane
substituted at positions 1, 2 and 3
by hydroxyl groups.
Hydrocarbons
▪ Long chains of carbon and
hydrogen atoms.
▪ Organic compounds; composed of
only carbon and hydrogen
▪ Insoluble in water (hydrophobic)
FATTY ACID
▪ A naturally occurring
monocarboxylic acid
SATURATED FATS
▪ Contains only a single bond in the
fatty acid chain.
▪ Found in animal fats.
▪ Also found in butter, lard, cream,
cheese, and some processed foods
▪ Solid in nature
UNSATURATED FATS
▪ Mostly known as oils; contain
one or more double bonds in
the fatty acid chain.
▪ Normally liquid at room
temperature.
▪ Commonly found in plants such
as olive oil, coconut oil, and corn
oil
STEARIC ACID
▪ No double bonds
▪ Straight chain; solid at room
temperature
▪ Found in animal fats, butter, and
lard
OLEIC ACID
▪ One double bond
▪ Bent chain; liquid at room
temperature
▪ Found in olive and canola oils
LINOLEIC ACID
▪ Two or more double bonds.
▪ More flexible; liquid even when
chilled
▪ Found in corn, sunflower, and fish
oils
STEROIDS
▪ It has four fused carbon rings.
▪ Helps in regulating metabolism,
immune response, reproduction,
and other essential biological
processes.
Cholesterol
▪ A type of steroid found in cell
membranes
▪ When _______ hardens in blood
vessels, it may block blood flow,
causing medical problems.
Atherosclerosis
▪ a disease in which plaque builds
up inside your arteries
▪ caused by cholesterol hardening
in the blood vessels which hamper
or block the flow of blood.
▪ Arteries are blood vessels that carry
oxygen-rich blood to your heart and
other parts of your body.
STEROL
steroid alcohol found in major
organs such as the brain and blood
vessels
High-Density
Lipoprotein (HDL)
▪ the “good cholesterol”
▪ picking up excess cholesterols from tissues to bring them back to the liver
Low-Density
Lipoprotein (LDL)
▪ the “bad cholesterol”
▪ Delivers cholesterol to body cells, but too much can build up in arteries, which can lead to blockages and heart disease.
Testosterone
– develops and
maintains male
Progesterone and Estrogen
control the ovulation cycle
TRIGLYCERIDES
▪ Generally known as fats, they
contain a glycerol attached to three
fatty acids
▪ The body’s most concentrated
source of energy
PHOSPHOLIPID
▪ Makes up the cell or plasma
membrane, essential to the
structure and function of cells.
▪ helps in
maintaining the membrane’s stability
and selective permeability.
WAXES
▪ Esters formed from certain alcohols
and fatty acids
▪ Found in nature, providing
waterproofing and protection for
many organisms
Proteins
- are large, complex molecules that play
many critical roles in the body.
- They do most of the work in cells and
are required for the structure, function,
and regulation of the body’s tissues and
organ
Secondary Protein Structure
structure refers to the
localized, regular folded shapes within a
polypeptide chain, which are stabilized
by hydrogen bonds
Tertiary Protein Structure
structure is the overall
three-dimensional shape of a single
polypeptide chain, formed by the folding
of secondary structures (like alpha-
helices and beta-sheets) and stabilized
by interactions between amino acid side
chains.
Quaternary Protein Structure
Quaternary structure describes the final,
complex 3D arrangement of multiple
folded protein subunits in a multi-subunit
protein complex, held together by
noncovalent bonds
Enzymatic Proteins
- Proteins that act as biological catalyst
Enzymes
control the rate of chemical
reactions by weakening bonds, thus
lowering the amount of activation energy
needed for the reaction
Transport Proteins
- Embedded in the plasma membrane to
serve as channels/carriers for molecules
to enter or exit the cell.
Defense Proteins
An antibody, also known as an
immunoglobulin, is a large, Y-shaped
protein produced mainly by plasma cells
that is used by the immune system to
neutralize pathogens such as bacteria
and viruses.
Structural Proteins
- are proteins that living organisms use
to maintain their shape or structural
integrity.
- Some common structural proteins are
keratin, collagen, elastin actin, and
myosin.
COLLAGEN
- It provides structural support to the
extracellular space of
connective tissues.
- Due to its rigidity and resistance to
stretching, it is the perfect matrix for
skin, tendons, bones, and ligaments.
ELASTIN
rubber band — it can stretch out
(extend) and shrink back (recoil).
- It's a major component of tissues in
your body that require stretchiness, like
your lungs, bladder, large blood vessels
and some ligaments.
KERATIN
- Keratins helps form the tissues of the
hair, nails, and the outer layer of the
skin.
- They are also found on cells in the
lining of organs, glands, and other parts
of the body.
Enzymes
are biological catalysts
responsible for supporting almost all of
the chemical reactions that maintain
animal homeostasis.
Lock and Key Model
• Model
• Emil Fischer (1894)
• Both the enzyme and the substrate
possess specific complementary
geometric shapes that fit exactly into
one another.
Rosalind Franklin
- produced critical images through Xray
diffraction that provided key insights into
DNA’s helical structure.
James Watson and Francis Crick
- received the Nobel Prizein 1962 for the
structure of DNA
Franklin’s vital contribution was largely
overlooked during her lifetime, raising
ongoing debates about scientific ethics,
recognition, and gender bias in science.
Nucleic Acids
Store hereditary information
- Contain information for making all the
body’s proteins
- Two types exist --- DNA & RNA
Nucleotides
are covalently linked together by
phosphodiester bonds
- A phosphate connects the 5’ carbon of
one nucleotide to the 3’ carbon of
another
Therefore, the strand has directionality
- 5’ to 3’
Ribonucleic acids
Encode, decode, and regulate the
expression of genes,
depending on the type of RNA present
Messenger RNA
- serves as a temporary copy of a gene
in the DNA that directs the sequence of
amino acids during protein synthesis.
Transfer RNA
- translates the sequence of amino acids
in a gene to create the correct sequence
of amino acids during protein synthesis.
Ribosomal RNA
- forms the peptide bonds between
amino acids in a polypeptide
ATP (Adenosine Triphosphate)
• Needed by plants and animals to
survive.
• The more complex an organism is, the
more ATP it needs.
Exergonic reactions
releases energy e.g. hydrolysis of
ATP: energy is transferred when ATP
breaks down into ADP
Endergonic reactions
require energy e.g. dehydration
synthesis: builds molecules up at the
expense of energy; heat and light
energy are needed for glucose to be
produced during photosynthesis
Autotrophs
produce their own food
for energy
Heterotrophs
– eat other organisms to
get energy
Cellular Respiration
a set of metabolic reactions and
processes that take place in the cells of
organisms to convert chemical energy
from food and oxygen molecules into
usable energy (ATP)
Aerobic
➢ requires oxygen
➢ occurs inside the mitochondria
➢ produces – 36 – 38 ATPs per
glucose molecule
➢ usually done by eukaryotes
ONLY.
Anaerobic
➢ does not require oxygen
➢ occurs in the cytoplasm
➢ produces 2 ATPS per glucose
molecule
➢ usually done by eukaryotes
and prokaryotes
Krebs cycle Citric Acid Cycle
• named after Hans Adolf Krebs (1900-
1981)
• cyclical metabolic pathway that occurs
in the mitochondrial matrix
• turns two (2) times for every glucose
molecule because of the 2 Acetyl – CoA
FERMENTATION
An anaerobic type of cellular respiration
produces a limited amount of ATP in
the absence of oxygen.