MIBO Ch 14: The Innate Immune Response

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5 Terms

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innate defenses

proactive in keeping out microbes

limited in identifying “foreigners”

pattern recognition

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adaptive defenses

specialized

must learn foreigner first then will “remember”

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innate first line defenses

physical barriers

antimcrobials

normal flora/microbiota

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physical barriers

skin - epithelial cells

mucous membrane (surface inside the body) - cilia, mucus, peristalsis, mucociliary escalator, urine

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antimicrobial substances

sweat - high salt

lysozyme - targets peptidoglycan

peroxidase enzymes - produces oxidizing compounds

lactoferrin - iron binding

defensins - disrupt bacterial membranes