Live Attenuated Vaccines

Flashcards covering the mechanism of action, cellular processing, immune activation, memory formation, contraindications, and examples of live attenuated vaccines.

Live attenuated vaccines

Vaccines that deliver live, weakened viruses that replicate within the body's cells, mimicking a natural infection to stimulate an immune response.

Varicella vaccine

An example of a DNA virus vaccine that replicates in the nucleus of host cells to naturally produce viral proteins.

MHC molecules

Host cell surface molecules that present processed viral proteins from replication, initiating a broad activation of the immune system.

Immune system activation (live attenuated vaccines)

The comprehensive immune response triggered by viral antigen presentation via MHC molecules, involving antigen-presenting cells, cytotoxic cells, and helper T cells.

Memory B and T cells

Immune cells formed as a result of the natural infection-like state and broad exposure to multiple viral antigens, providing long-lasting immunity upon re-exposure.

Weakened immunity contraindication

The condition of having an impaired immune system, which renders individuals not suitable for receiving live attenuated vaccines.

MMR and chickenpox

Diseases targeted by representative examples of live attenuated vaccines.