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ch-17
Phineas Gage case
25yr old who had iron rod in face affected medical prefrontal lobes (planning,decision making, and emotion)
17-limbic sys
amygdala, fear conditioning emotional memory and social cognition
17-Ekman and Friesens primary emotional expressions
fear, happiness, anger, sadness, disgust, surprise
17-hans selye
identified adrenal cortex in stress response→sympathetic nervous sys, generalized stress concept
17-cannon-bard theory
emotional stimuli have 2 independent excitatory effects excite feeling of emotion in the brain and expression of emotion in ans and sns
17-in functional brain-imaging studies emotional situations typically produce increases in cerebral activity that are
widespread, rather than limited to amygdalae and prefrontal cortex
17-disorders whose symptoms are primarily physical but whose development is greatly influenced by psychological factors are called
psychosomatic disorders
17-psychoneuroimmunology
field that studies the stress effects in immune system function
17-adrenocorticotropic hormone(ACTH)
anterior pituitary, triggers release of glucocorticoids
17-glucocorticoids
from adrenal cortex
17-the immune sys has 2 components the innate sys and
the adaptive immune sys
17-gastric ulcers- h.pylori
casual factor, caused by stress
17-stress vs estress
bad distress, good
17-the stress response
physiological response to harm or threat
17-the most commonly used measure of stress
level of circulating glucocorticoids
17-lateral nucleus and the amygdala relationship with fear
involved in acquisition, storage, and expression of conditioned fear
17-the amygdala is thought to control defensive behavior via outputs from the
central nucleus of the amygdala
17-which neural structure has a particularly dense population of glucocorticoid receptors?
hippocampus
17-testosterone
does not cause agression
17-emotional significance of sensory signals is learned and retained in the
amygdala
17- lateral nucleus plays key role in
auditory fear conditioning
18- schizophrenia
early adulthood
+)delusions*, hallucinations*, inappropriate affect, disorganized speech*, odd behavior
-)affective flattening, avolition, catatonia
antipsychotics- chlorpromazine , reserpine 2nd
too much dopamine
18- Bipolar disorder
abnormal activity in frontal cortex; and striatal reward circuits smaller hippocampus
mood stabilizers- lithium 1st, metallic ion
type 1- depression w/ or w/o mania(extreme)
type 2- depression w/hypomania
highest rates of suicide and attempted
mixed state- severe depression and mania (suicide)
euthymic- no symptoms of depression, mania, or hypomania
teens-middle adulthood 25yrs
18- major depressive disorder
selective norepinephrine - reuptake inhibitors(SNRI)
…………. serotonin……………………………………(SSRI)
2x more likely in women any age
prozac-fluoxetine is SSRI
reactive-triggered by obvious negative event
endogenous-no apparent cause
18- anxiety disorders
benzodiazepines-(Librium, valium) agonist action on GABA
anxiolytic agonist at GABAA receptors or serotonin receptors
worry of events or activities chronic fear
agoraphobia- fear of open spaces
most prevalent of all
prefrontal cortex, hippocampus, and amygdala
18- tourettes disorder
tics degains early in life
1st educate, 2nd focus on emotional problems, 3rd treat tics (antipsychotics)
changes in cortical-striatal - thalamic cortical circuit