Hereditary angioedema

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Last updated 10:08 AM on 9/22/26

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Mutated gene

SERPING1 gene

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SERPING1 gene encodes

C1 INH

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Pathophysiology

Deficiency or dysfunction of C1 esterase inhibitor ——> uncontrolled activation of kallikrein - bradykein system

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C4 level

Reduced

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C3 level

Normal