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PDC
multienzyme complex
3 enzymes
5 reactions
reaction 1
transfer acetyl group from pyruvate to TPP to make hydroxyethyl-TPP
reaction 1 enzyme
E1
reaction 2
transfer of acetyl group from hydroxyethel-TPP on E1 to Lipoamide of E2 to make acetyl-dihydrolipoamide
reaction 2 enzyme
E2
reaction 3
acetyl group transfered to CoA to make acetyl CoA
reaction 3 enzyme
E2
reaction 4
dihydrolipoamide oxidized, 2 electrons to FAD to get FADH2
reaction 4 enzyme
E3
reaction 5
FADH2 oxidized by NAD+ to NADH + H+