amino acid groups

Gly, Ala, Val, Leu, Ile, Met, Pro, Phe, and Trp are all examples of what kind of amino acid?

nonpolar/hydrophobic

Ser, Thr, Cys, Tyr, Asn, and Gln are all examples of what kind of amino acid group?

polar uncharged

Asp and Glu are examples of what kind of amino acid group?

negative

Lys and Arg are examples of what kind of amino acid group?

positive/basic

His is an example of what kind of amino acid group?

titratable

what are examples of special side-chain properties?

Gly, Pro, Cys, His

what are examples of aromatics?

Phe, Trp, Tyr, His

what are some negative (acidic) side chains that carry charge near pH 7.4?

what are some positive (basic) side chains that carry charge near pH 7.4?

histidine’s charge mostly depends on pH, what is it most neutral at?

pH 7.4

what are some side-chain features of Gly?

small, flexible, fits tight turns

what are some-chain features of Pro?

ring constrains the backbone → kinks

what are some side-chain features of Cys?

thiol → forms disulfide cross-links

what are some side-chain features of His?

proton transfer near physiological pH

what are some side-chain features of Ser, Thr, Tyr?

-OH groups → sites for phosphorylation

what are some side-chain features for Phe, Tyr, Trp?

aromatic rings → hydrophobic, stacking