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Cranium is broken into 2 parts
Neurocranium - top of skull; calvaria (hat) and cranial base
viscerocranium - bottom where jaw is
Fontanelles
soft spots in infants because cranium hasn’t been fully formed
Pterion
frontal, parietal, temporal, and sphenoid bone meets here. Very weak. Middle meningeal artery is here
Lamda
lambdoid and sagittal suture
Bregma
Coronal and sagittal suture
Asterion
lambdoid and squamous suture
Sella turcica
Clinoid processes and hypophysial fossa
Foramen cecum
nasal emissary veins
Cribriform foramina
olfactory nerves (CN I)
Optic Canals
Optic nerves (CN II)
Ophthalmic arteries
Superior orbital fissures
Ophthalmic veins
Trigeminal - Ophthalmic nerve (CN V1)
Oculomotor nerve (CN III)
Trochlear nerve (CN IV)
Abducens nerve (CN VI)
Foramen rotundum
Trigeminal - Maxillary nerve (CN V2)
Foramen ovale
Trigeminal - Mandibular nerve (CN V3)
Accessory meningeal artery
Foramen spinosum
middle meningeal artery and vein
Trigeminal - Meningeal branch of mandibular (CN V3)
Foramen lacerum
gets filled as we age
Internal acoustic meatus
Facial nerve (CN VII)
Vestibulocochlear nerve (CN VIII)
Jugular foramen
Glossopharyngeal nerve (CN IX)
Vagus nerve (CN X)
Spinal accessory nerve (CN XI) (exits)
Internal petrosal and sigmoid sinuses become internal jugular vein
Hypoglossal canal
Hypoglossal nerve (CN XII)
Foramen magnum
medulla
meninges
vertebral arteries
spinal accessory nerve (CN XI) (enters)
Dural veins
anteiror and posterior spinal arteries
Carotid canal
internal carotid artery
stylomastoid foramen
facial nerve (CN VII)
stylomastoid artery
Meninges
dura mater
arachnoid mater
pia mater
Dura mater
innervated
vascular → middle meningeal artery
2 layers: external periosteal layer (stuck to skull) and internal meningeal layer (forms dural infolds and stuck to brain)
arachnoid mater
not innervated / not vascular
bridging veins
Pia mater
innervated
vascular → cerebral arteries and veins
Falx cerebri
crista galli to occipital protuberance
Tentorium Cerebelli
Clinoid processes (sphenoid) petrous part of temporal bone to occipital / parietal bones
Falx cerebelli
occipital bone - tentorium cerebelli
Diaphragma sellae
roof over hypophyseal fossa (sphenoid)
Meningeal spaces
Epidural space: not a natural space
Dura mater: subdural space: not a natural space
Arachnoid mater: subarachnoid space: CSF
Pia mater: no space
Hemorrhage
excessive bleeding
Hematoma
clot
Epidural (extradural) hemorrhage
Middle meningeal artery → supplies blood to dura mater
trauma
subdural hematoma
“bridging” veins (cerebral and cerebellar veins) → cross subdural space to drain superficial brain into venous sinuses
trauma
subarachnoid hemorrhage
cerebral arteries → supply cerebrum
aneurysm
Petrosal sinuses
superior petrosal sinus drains into transverse sinus
inferior petrosal sinus drains into internal jugular vein
Cavernous sinuses
Oculomotor nerve (CN III)
Trochlear nerve (CN IV)
Trigeminal - Ophthalmic branch (CN V1)
Trigeminal - Maxillary branch (CN V2)
Internal carotid artery
abducens nerve (CN VI)
trochlear nerve (CN IV)
OTO MCAT
Blood supply to meninges
external carotid artery → maxillary artery → middle meningeal artery
Meningitis
viral infection, bacterial, or fungal
symptoms: headache, fever, vomiting, nuchal ridigity (stiff neck)
neck flexion test
Cerebrospinal fluid
Formation: choroid plexus
Ependymal cells: neuroglial cells, helps protect brain, filtering systems, pulls plasma from blood into ventricular system
flow: ventricles makes CSF mostly in lateral ventricles
Flow of CSF
Lateral ventricles → interventricular foramen → third ventricle → cerebral aqueduct → fourth ventricle → lateral / medial apertures → subarachnoid space and central canal in spinal cord
Subarachnoid cisterns
extended regions of subarachnoid space with pockets of CSF to help with bounancy
Arachnoid granulations
super sagittal sinus has the most
drain CSF from subarachnoid space into bloodstream
Hydrocephalus
blockage of CSF flow causes enlargement of ventricles behind the blockage
Pre central gyrus
motor
post central gyrus
sensory
somatosensory
whole body sensory: feel your tongue
Nuceli
collection of somas in central nervous system (brain and spinal cord)
ganglia
collection of somas in peripheral nervous system
nerve
collection of axons in peripheral nervous system
tract
collection of axons in central nervous system
White matter vs. gray matter
white matter: axons
gray matter: somas
Commissural tracts
connect different hemispheres
Association tracts
stays in the same hemisphere
Projection tracts
connects superior / inferior, up and odwn
Broca’s area
production of speech, making words, etc
Wernicke’s area
Comprehension of speech; being able to understand
Aphasia
disorder that affects how you communicate
Basal nuclei / ganglia
caudate nucleus, putamen, globus pallidus
filters unwanted movement ex: resting tremors: hand shaking at rest is an unwanted movement
Telencephalon
amygdala: emotional responses related to memory
hippocampus: memory
cingulate gyrus: regulating behavior response regarding to emotion
controls emotional response and memory processing
Hypothalamus
integration center for autonomic nervous system ex: temperature, thirst
regulation of endocrine system; hypothalamus tells pituitary gland what to do
Pituitary gland
hormones
Pineal gland
regulates circadian rhythm
Midbrain
Relay center that connects different structures; communicating
superior colliculus - visual reflex center
inferior colliculus - auditory reflex center
Pons
projection fibers connect higher brain centers and spinal cord
relay impulses between motor cortex and cerebellum
changes respiratory rate, but doesn’t start it
Medulla oblongata
heart rate
respiratory rate (starts it)
blood pressure
vomiting
coughing
nuclei of cranial nerves