411 Nucleotide Metabolism List of Drugs: Chemotherapy indications

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Last updated 2:51 AM on 10/2/26

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6-Mercaptopurine

Purine (Guanine) analog
Chemotherapy

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gemicitabine

cytosine analog
chemotherapy

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cladribine

adenosine analog
chemotherapy

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5-fluorouracil (5-FU)

uracil analog, inhibits TS
chemotherapy

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Aminopterin (antifolate)

Mammalian DHFR, folate analog
chemotherapy

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Capecitabine

Mammalian DHFR and Thymidylate synthase, folate analog
Chemotherapy and autoimmune conditions

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Pemetrexed (antifolate)

Mammalian DHFR, TS, GARFT, folate analog
chemotherapy