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Cartilage functions
Supports soft tissue
Provides a gliding and/or cushioning surface at joints
Flexibility in bone structures
Provides a model for bone growth
Interstitial growth
from inside of cartilage
Appositional growth
along opposite edge and stem cells to become chondrocytes
Bone functions
structural support, protection, movement, mineral storage, blood cell production in red bone marrow, and storage of lipids
Long bones
greater length than width, diaphysis, epiphyses, metaphyses, humerus
Short bones
nearly equal length and width
Flat bones
flat and thin surfaces, skull
Irregular bones
complex shapes like vertebrae
Sesamoid bones
formed in tendons
Bone constituents: Cells
1% of bone weight, osteoprogenitors, osteoblasts, osteocytes, and osteoclasts
Osteoprogenitors
mesenchymal stem cells which are found in deep endosteum and peristeum
Osteoblasts
secrete organic form of bone matrix called osteoid (mostly collage)
Osteocytes
mature osteoblasts that have become trapped inside lacunae and maintain matrix
Osteoclasts
large, multinucleted phagocytes that dissolve bone, releasing minerals
Matrix
Inorganic and organic components
Inorganic
makes up 2/3, calcium phosphate and calcium hydroxide interact to form crystals of hydroxyapatite (hardens bone matrix)
Organic
makes up 1/3, collagen fibers and ground substance
Head
bony expansion of a narrow neck, head of femur
Condyle
rounded articular projection, later condyle of femur
Facet
smooth, nearly flat articular surface, superior articular facet
Ramus
angular extension of bone, mandibular ramus
Tuberosity
a large, rough, and rounded bump on a bone where muscles, tendons, and ligaments attach, ischial tuberosity
Crest
narrow, prominent ridge of bone
Trochanter
a prominent, bony projection on the upper part of the thighbone (femur) that serves as an attachment site for hip and thigh muscles, greater trochanter
Line
subtle, narrow, and faint raised ridge or narrow stripe on a bone that serves as an attachment point for muscles, tendons, or ligaments, linea aspera
Tubercle
small, rounded projection, bump, or eminence on a bone that usually serves as an attachment site for muscles, tendons, or ligaments, greater tubercle
Epicondyle
a raised bump or projection on a long bone, located just above or on the articular surface of a joint, that serves as a vital attachment point for muscles, tendons, and ligaments, medial epicondyle
Spine
thin bone projection, scapula
Process
any bone prominence, styloid process
Sinus
cavity within a bone, frontal sinus
Fossa
shallow, basin line depression, olecranon fossa
Groove
narrow depression
Fissure
narrow, slit-like opening through bone, superior orbital fissure
Foramen
round oval opening through bone, foramen magnum
Canal
passageway through bone, meatus is the same
Spongy bone
porous, consists of lattice of narrow plates (trabecular), forms internal structures, red bone marrow
Compact bone
dense and cortical bone, solid, forms external portions of flat and long bones
Compact bone constituent
osteon, central canal, lamellae, lacunae, canaliculi, perforating canals, interstitial lamellae, circumferential lamellae
Osteons
basic structural and functional units of bone
Central canal
carries blood vessels through center of osteons, haverisans
Lamellae
concentric: rings of bone around a central canal (osteocytes sit in here)
Lacunae
small, spindle-shaped cavities or spaces located between the lamellae (concentric rings) of bone matrix that house mature bone cells called osteocyte
Canaliculi
small cnals between lacunae, allowing interactions between osteocytes
Perforating canals
perpendicular connections between central canals
Interstitial lamellae
leftover pieces of old osteons
Circumferential
along endosteum and periosteum
Spongy bone: trabeculae
basic structure and functional units of spongy bone
Ossification type: Endochondral
hyaline cartilage model forms and then is replaced by bone
Ossification type: intramembranous
thickened deposits of mesenchyme become mineralized
Bone growth: interstitial
from inside of cartilage, increases in length
Bone growth: appositional
along opposite edge of cartilage, increases in thickness or diameter
Zone of Resting cartilage
farthest from diaphysis, chondrocytes in hyaline cartilage
Zone of proliferating cartilage
large chondrocytes undergoing rapid miotic cell division
Zone of hypertrophic cartilage
chondrocytes become enlarged
Zone of calcified cartilage
deposited minerals kill chondrocytes
Zone of ossification
Resorption/Bone Deposition Zone, closest to diaphysis
What type of bone growth is occurring at the ephiphyseal plate?
Interstitial growth
Why is bone continuously remodeled?
In response to mechanical stress, repair microdamage, maintain bone strength, and regulate mineral levels
Which cells build bone?
osteoblasts
Which cells resorb bone?
Osteoclasts
Why does growth in length of long bones cease?
The growth plates will completely ossify and fuse to solid bone
Wolff’s law
Bone is deposited where it is needed and resorbed where it is not needed
How does the balance between growth and resorption of bone change as an individual ages?
As a person ages bone resorption increases and bone deposition decreases
Germ cell layer that derives bone
Mesoderm
When does ossification occur?
Between sixth and seventh weeks of embryonic development
Axial skeleton
skull, hyoid, vertebrae, thoracic cage
Appendicular skeleton
shoulder girdle, arms, pelvic girdle, legs
Paired neurocranial bone
Parietals and temprals
Unpaired neurocranial bones
frontal, occipital, sphenoid, ethmoid
Paired Facial bones
zygomatic, lacrimals, nasals, inferior nasal, concnae, palatine, maxilla
Unpaired facial bones
vomer and mandible
Foramen magnum
in the occipital and bone, passageway for the spinal cord from skull to vertebral column
Cribriform plate
ethmoid bone, passageway of olfactory nerve endings
External acoustic meatus
temporal bone, opening in skull to ear
Orbits
bony cavities that encase eyes and fatty tissued, formed by: sphenoid, ethmoid, zygomatic, lacrimal, etc
Optic canals
sphenoid bone, passgeway of optic nerves from brain to eye
Nasal cavity
regulates air temps, humidifies air, formed by the ethmoid, sphenoid, nasal, and maxilla
Nasal conchae
scrolled spongy bones that portrudes into nasal passageway
Paranasal sinuses
connected to nasal cavities, mucosa lined and filled, decreases weight of skull, moistens air, provide resonance to voice
Sutural bones
coronal suture, sagittal suture, lambdoid suture, squamous suture
Jaws and teeth
maxillae and mandible, form upper and lower jaws, house teeth
Intervertebral disks
fibrocartilage, shock absorbers, between vertebrae
Annulus fibrosus
encloses nucleus pulposus
Nucleus pulposus
he soft, jelly-like center of the intervertebral disc that acts as a shock absorber between the bones of the spine
Body of vertebrae
to support and bear the heavy weight of the upper body and torso
Spinous process
pointy and thin
Superior articular facet
an upward-facing bony surface on a vertebra that connects with the inferior (downward-facing) facet of the vertebra directly above it
Inferior articular facet
guides spinal movement and supports body weight
Vertebral foramen
the large, central hole in each individual vertebra that allows the spinal cord to pass through
Atlas (c1)
no body; superior articular facets allow head nodding
Axis (C2)
dens of axis inserts into atlas and allows head rotation
Dens axis
a prominent tooth-like vertical projection rising from the body of the second cervical vertebra (C2 axis
Cervical
7, concave, secondar
Thoracic
12, convex, primary
Lumbar
5, concave, secondary
Sacral
5, convex, primary
Coccyx
2-4