Discovery and Fundamental properties of X-Rays, Radiological Effects and Theory of Risk Management

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Last updated 11:38 PM on 10/17/26
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140 Terms

1
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Who discovered X-rays and in what year?

Wilhelm Röntgen in November 1895.

<p>Wilhelm Röntgen in November 1895.</p>
2
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What material fluoresced in Röntgen's initial X-ray experiment?

Barium platinocyanide-coated paper.

<p>Barium platinocyanide-coated paper.</p>
3
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What is the propagation speed of X-rays in a vacuum?

The speed of light (3 × 10⁸ m/s).

<p>The speed of light (3 × 10⁸ m/s).</p>
4
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Why can X-rays not be focused by optical lenses?

They are high-energy photons that do not refract like visible light.

<p>They are high-energy photons that do not refract like visible light.</p>
5
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What electric charge do X-ray photons carry?

They are electrically neutral (zero charge).

<p>They are electrically neutral (zero charge).</p>
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What determines the maximum energy in a polyenergetic X-ray beam?

The peak kilovoltage (kVp) selected.

7
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What two mechanisms account for X-ray beam attenuation?

Absorption and scattering.

8
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How does X-ray scatter affect photographic film or detectors?

It causes fogging and reduces image contrast.

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Who was the first person known to die from X-ray exposure?

Clarence Dally in 1904.

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Which scientist won a Nobel Prize for discovering X-ray genetic effects?

H.J. Muller in 1927.

11
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What are the complementary DNA base pairs?

Adenine with Thymine, and Cytosine with Guanine.

<p>Adenine with Thymine, and Cytosine with Guanine.</p>
12
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What happens if a cell fails to repair significant DNA damage?

It undergoes apoptosis (programmed cell death).

<p>It undergoes apoptosis (programmed cell death).</p>
13
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What are deterministic radiation effects?

Effects caused by cell death with a dose threshold; severity increases with dose.

14
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What are stochastic radiation effects?

Probabilistic effects without a threshold; chance increases with dose, but severity does not.

15
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Which health outcome is an example of a stochastic radiation effect?

Radiation-induced cancer.

16
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What does LD₅₀ signify in radiation biology?

The radiation dose that is lethal to 50% of a population.

<p>The radiation dose that is lethal to 50% of a population.</p>
17
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What are the radiation thresholds for the three main Acute Radiation Syndrome (ARS) forms?

Hematopoietic (1 Gy), Gastrointestinal (6 Gy), and Neurovascular (30 Gy).

<p>Hematopoietic (1 Gy), Gastrointestinal (6 Gy), and Neurovascular (30 Gy).</p>
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Which human cell types have the lowest radiosensitivity?

Nerve cells and muscle cells.

19
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Which human cell types have high radiosensitivity?

Blood cells, thyroid cells, eye lens cells, and gonadal cells.

<p>Blood cells, thyroid cells, eye lens cells, and gonadal cells.</p>
20
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What do DICOM and PACS standards facilitate in radiology?

Standardized storage, management, and transmission of medical images.

21
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How is Risk conceptually calculated?

Risk = likelihood × severity.

22
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What is Risk Management in clinical imaging?

The systematic process of identifying, assessing, and controlling risks to minimize harm.

23
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What are the 5 steps of Risk Management?

1. Identify hazards 2. Assess risks 3. Control risks 4. Record 5. Review.

24
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What is the Hierarchy of Control from most to least effective?

Eliminate hazard, substitute, engineering controls, administrative controls, PPE (last resort).

<p>Eliminate hazard, substitute, engineering controls, administrative controls, PPE (last resort).</p>
25
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What does ALARP stand for in radiation safety?

As Low As Reasonably Practicable.

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What does 'reasonably practicable' mean in the ALARP principle?

Further risk reduction is not required if effort/cost is grossly disproportionate to the benefit.

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Which legislation principle is supported by ALARP in radiography?

The IR(ME)R principle of dose optimization.

28
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What incident reporting software is commonly used in the NHS?

Datix.

29
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What equipment was Röntgen experimenting with when he noticed the platinobarium screen glowing?

A cathode ray tube.

30
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What was the result when Röntgen placed his hand between the tube and the coated screen?

He realized he could see the bones.

31
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What other items did Röntgen explore with his rays?

A spool of wire inside a case and a compass in an enclosed box.

32
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Who placed her hand on the photographic plate to produce the first x-ray?

Anna Bertha Lüdwig-Röntgen, Röntgen's wife.

33
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How quickly did x-rays take the world by storm after their discovery?

Within a month.

34
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In what year were x-rays first used to identify a Colles fracture and in early radiotherapy?

1896.

35
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Who discovered the electron in 1897?

Thomson.

36
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Who discovered radioactivity in 1896?

Bacquerel.

37
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Who discovered radium and polonium in 1898?

The Curies.

38
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X-ray travel path

Straight line; precise positioning is essential to prevent distortion, magnification, or missed anatomy.

39
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X-ray penetration

Depends on incident photon energy and the density/thickness of the penetrated object.

40
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Impact of incorrect kVp levels

Too low results in insufficient detector signal; too high causes over-exposure.

41
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Three interactions of X-rays with matter

Absorption, scatter, and transmission.

42
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Role of absorption in X-ray imaging

Provides adequate contrast as bone, soft tissue, and air absorb different amounts of radiation.

43
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Effect of X-ray scatter

Creates noise and increases radiation exposure, which practitioners attempt to reduce.

44
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X-ray ionising nature

Interacts with detectors and biological tissue to produce images but carries risks that require regulation.

45
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Mass and charge of X-rays

X-rays have no mass or charge and are not influenced by electromagnetic fields.

46
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Polyenergetic nature of X-rays

The beam contains photons of a variety of energies and must be managed for dose reduction and image quality.

47
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Manipulation of X-ray beams

Cannot be focused by optical lenses due to high energy and short wavelength, requiring mechanical manipulation.

48
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Fluorescence and biological changes from X-rays

Causes materials to fluoresce (used in imaging) and causes biological changes (used in therapy with side effects).

49
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X-ray safety indicators

Signs and warning lights must indicate active X-rays because the beam is invisible to the human eye.

50
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Clinical Governance Pillars

Consists of 7 pillars that guide healthcare quality, safety, and professional standards.

51
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HCPC Student Guidelines on Risk

Take steps to limit harm, follow risk policies, avoid danger, and seek support if health affects performance.

52
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Clinical Relevance in Radiography

Protects patients and staff from harm, maintains public trust, and promotes legal and professional compliance.

53
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Benefits of Risk Management

Proactively identifies risks, ensures consistent standards, reassures patients, and builds a positive safety culture.

54
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Five Steps of Risk Management

1. Identify risks 2. Assess likelihood 3. Implement controls 4. Record changes 5. Review and monitor.

55
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Radiology Hazard Examples

Radiation exposure, patient falls, equipment failure, manual handling injuries, and documentation errors.

56
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Controlling Risks in Radiology

Using lead screens, appropriate manual handling training, and regular equipment maintenance.

57
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Recording and Reviewing Findings

Completing Datix reports, conducting audits on risk and control measures, and using errors as learning points.

58
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Logarithmic Scales

Increments increase by multiples of 10, allowing pattern identification across a wide range of data.

59
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Radiographer's Role in Safety

Following policies, reporting hazards and near-misses, participating in audits, and reflecting on incidents.

60
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Rectangular collimation

Restricts and confines the X-ray beam to minimise radiation exposure.

61
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Focus-to-skin distance

At least 20cm, but preferably 30cm.

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Use of film holders

Allows for precise positioning of the film.

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Digital receptors vs conventional film

Digital receptors typically require lower radiation doses.

64
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Minimising image number

Reduce the number of images to the minimum required for diagnosis.

65
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Limiting CBCT usage

Limit the use of cone beam computed tomography.

66
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Radiograph justification recording

Must always be recorded in patient notes, as required under IR(ME)R.

67
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Harmful effects of early X-rays

erythema (skin reddening) and burns; early reports of injury—previously thought nonexistent—arose from patients, tube manufacturers, and predominantly those delivering X-rays to patients, with Clarence Dally becoming likely the first fatality.

68
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What is radiobiology?
The study of the effects of radiation on living organisms.
69
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What are stochastic effects?
Radiation effects that occur randomly, with probability increasing as dose increases.
70
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What does stochastic mean?
It means an effect involves an element of chance or randomness.
71
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How does increasing dose affect stochastic risk?
Risk increases with dose; the relationship is assumed linear under the linear-no-threshold hypothesis.
72
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Does the severity of stochastic effects depend on dose?
No. Dose increases the probability of an effect, not its severity.
73
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What is the linear-no-threshold (LNT) hypothesis?
It assumes radiation risk increases linearly with dose, with no threshold below which risk is zero.
74
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What analogy illustrates stochastic effects?
Throwing marbles at a small bucket: more throws increase the chance of a marble entering, but it could happen on the first throw.
75
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What are deterministic effects, also called tissue reactions?
Radiation effects that generally occur only after a threshold dose is exceeded.
76
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What happens to deterministic effect severity as dose increases above the threshold?
Severity generally increases as dose increases.
77
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What is the typical threshold listed for deterministic effects in the lecture?
Typically greater than 0.5 Gy, although thresholds vary by tissue and effect.
78
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Name five examples of deterministic effects.
Skin erythema, hair loss, cataracts, sterility and organ dysfunction.
79
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Name examples of stochastic effects from the lecture.
Cancer, genetic mutations and foetal defects.
80
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How does onset typically differ between deterministic and stochastic effects?
Deterministic effects may appear within hours to days; stochastic effects may appear years later or across generations.
81
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What is the key difference between stochastic and deterministic effects?
Stochastic: probability increases with dose, severity is dose-independent. Deterministic: a threshold exists and severity increases above it.
82
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What is a survival curve used for?
To summarise survival following radiation exposure and illustrate dose-related lethal effects.
83
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What does LD50 mean?
The dose at which 50% of a specified population is expected to survive under defined conditions.
84
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What is a linear scale?
A scale with equal-sized numerical increments along an axis.
85
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What is a logarithmic scale?
A scale where equal steps represent multiplicative changes, often powers of ten.
86
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Why use a logarithmic scale?
To display a wide range of values and identify patterns across orders of magnitude.
87
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What is radiosensitivity?
The susceptibility of cells or tissues to damage from ionising radiation.
88
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How does radiosensitivity affect radiation effects?
More radiosensitive tissues may experience deterministic effects at lower doses and have a greater probability of stochastic effects at a given dose.
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90
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What happens when ionising radiation interacts with the human body?
Energetic electrons are produced, which can cause direct or indirect DNA damage.
91
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What are the two main pathways of radiation-induced DNA damage?
Direct damage to DNA and indirect damage caused by reactive free radicals.
92
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What is direct DNA damage?
Radiation-produced energetic electrons directly damage DNA, including its backbone.
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What is indirect DNA damage?
Radiation causes reactive free radicals to form, which can damage DNA and mutate its base pairs.
94
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What are the Compton and Photoelectric effects?
Interactions of X-rays with matter that can produce energetic electrons within the body.
95
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How do energetic electrons cause tissue damage?
They deposit energy locally, causing ionisation and cellular damage.
96
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What happens when an X-ray photon interacts with an electron?
The photon may transfer energy to the electron, producing an energetic electron if sufficient energy is transferred.
97
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What is the Compton effect?
The photon transfers some of its energy to an electron, ejecting it; the photon scatters with reduced energy.
98
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What happens if a photon does not transfer enough energy to free an electron?
The energy may be transferred to the material and dissipated as heat, depending on the interaction.
99
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What is the Photoelectric effect?
A photon is completely absorbed by an atom and ejects a bound electron.
100
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What is direct DNA damage?
Radiation-produced energy directly damages DNA, including its backbone.