enzymes of glycolysis cycle - chapter 13

PHR 3200

hexokinase

• step 1

• uses 1 ATP

• 0 NADH formed

• Glucose to G6P

Phosphofructokinase - 1 (PFK - 1)

• step 3

• uses 1 ATP

• 0 NADH formed

• F6P to F16BPG

GAPDH (glyceraldehyde - 3- phosphate dehydrogenase)

• step 6

• no ATP used

• 2 NAHD formed

• GAP to 1,3- BPG

Phosphoglycerate kinase (enzyme)

• step 7

• produces 2 ATP

• 0 NADH formed

• 1,3 - BPG to 3- phosphoglycerate

Pyruvate Kinase

• step 10

• produces 2 ATP

• 0 NADH formed

• 2- phosphoglycerate to pyruvate

Glucose - 6 - phosphate (G6P)

slow down glycolysis cycle

what inhibits hexokinase

AMP and F2,6BP

speed up glycolysis

what activates of PFK - 1

High ATP

slow down glycolysis cycle

what inhibits PFK - 1

fructose - 1,6 - bisphosphate (F16BP)

increase glycolysis cycle

what activates pyruvate kinase

High ATP

slow down glycolysis cycle

what inhibits pyruvate kinase