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What is the Krebs cycle also known as?
citric acid cycle
Where does the Krebs cycle occur?
mitochondrial matrix
What is stage 1 of the Krebs cycle?
converting acetyl coenzyme A into citrate
Outline stage 1 of the Krebs cycle as converting acetyl coenzyme A into citrate (5)
acetyl coenzyme A is a 2-carbon molecule, oxaloacetate is a 4-carbon molecule, acetyl coenzyme A and oxaloacetate react to form citrate, citrate is a 6-carbon molecule, at the same time this reaction is occurring coenzyme A is released to be reused in the prior stage of the link reaction
What is stage 2 of the Krebs cycle?
decarboxylation and dehydrogenation of citrate
Outline stage 2 of the Krebs cycle as decarboxylation and dehydrogenation of citrate (decarboxylation) (3)
citrate loses a carboxyl group releasing carbon dioxide as a waste product, a 5-carbon intermediate molecule is formed, 5-carbon intermediate molecule is also decarboxylated forming 4-carbon oxaloacetate again
Outline stage 2 of the Krebs cycle as decarboxylation and dehydrogenation of citrate (dehydrogenation) (4)
at the same time the decarboxylation is occurring, citrate and 5-carbon intermediate are dehydrogenated/oxidised, 3 coenzyme NAD molecules are reduced, 1 coenzyme FAD molecule is reduced
What is stage 3 of the Krebs cycle?
Substrate-level phosphorylation
Outline stage 3 of the Krebs cycle as substrate-level phosphorylation
1 ADP molecule and 1 inorganic phosphate group react to produce 1 molecule of ATP
What are the reactants of the Krebs cycle? (6)
1 x acetyl CoA, 1 x oxaloacetate, 3 x NAD, 1 x FAD, 1 x ADP, 1 x Pi
What are the products of the Krebs cycle? (6)
1 x CoA, 2 x CO2, 3 x NADH, 1 x FADH2, 1 x ATP, 1 x oxaloacetate
How many hydrogen atoms does coenzyme NAD accept?
1
How many hydrogen atoms does coenzyme FAD accept?
2